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The Journal of Laryngology & Otology The Journal of Laryngology & Otology

Article contents

Congenital syphilitic deafness—a further review

Published online by Cambridge University Press:  29 June 2007

D. A. Adams ,
A. G. Kerr ,
G. D. L. Smyth  and
M. J. Cinnamond
D. A. Adams
Affiliation:
Belfast
A. G. Kerr
Affiliation:
Belfast
G. D. L. Smyth
Affiliation:
Belfast
M. J. Cinnamond
Affiliation:
Belfast
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Abstract

Initial optimism about the successful outcome of treatment of congenital syphilitic deafness with ampicillin and steroids has always been tempered with an awareness of the uncertain long-term results. This paper is a review of 16 patients treated with various combinations of ampicillin and steroid; these have been followed up for periods of five to 14 years. Ampicillin alone does not prevent progressive hearing loss in the majority of patients. Ampicillin combined with prednisone, or with prednisone and ACTH, has preserved the hearing in all but two ears which had useful hearing before treatment The fact that the hearing in many of these ears, although maintained continues to fluctuate still gives cause for concern.

Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 97 , Issue 5 , May 1983 , pp. 399 - 404
Copyright
Copyright © JLO (1984) Limited 1983

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References

Becker, G. D. (1979) Late syphilitic hearing loss: a diagnostic and therapeutic dilemma. The Laryngoscope, 89: 1273.CrossRefGoogle ScholarPubMed
Kerr, A. G., Smyth, G. D. L. and Landau, H. D. (1970) Congenital Syphilitic Labyrinthitis. Archives of Otolaryngology, 91: 474.CrossRefGoogle ScholarPubMed
Kerr, A. G., Smyth, G. D. L. and Cinnamond, M. J. (1973) Congenital Syphilitic Deafness. Journal of Laryngology and Otology, 87: 1.CrossRefGoogle ScholarPubMed
Pillsbury, H. C. and Shea, J. J. (1979) Luetic Hydrops—diagnosis and therapy. The Laryngoscope, 89: 1135.Google ScholarPubMed
Smyth, G. D. L., Kerr, A. G. and Cinnamond, M. J. (1976) Deafness due to Syphilis. Journal of the Otolaryngological Society of Australia, 4: 36.Google Scholar
Zoller, M., Wilson, W. R. and Nadol, J. B. J. (1979) Treatment of Syphilitic Hearing Loss. Combined penicillin and steroid therapy in 29 patients. Annals of Otology, Rhinology and Laryngology, 88: 160.CrossRefGoogle ScholarPubMed
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