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The Journal of Laryngology & Otology The Journal of Laryngology & Otology

Article contents

Treatment of perennial allergic rhinitis by sodium cromoglycate plus 0.025 per cent xylometazoline

(a double-blind study)

Published online by Cambridge University Press:  29 June 2007

M. Fradis ,
L. Podoshin  and
R. Gertner
M. Fradis
Affiliation:
Haifa, Israel
L. Podoshin*
Affiliation:
Haifa, Israel
R. Gertner
Affiliation:
Haifa, Israel
*
Professor L. Podoshin, M.D., Haifa Medical Center (Rothschild), Department of Otolaryngology, P.O. Box 4940, Haifa 31 048, Israel.
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Summary

The object of this double-blind study was to assess the therapeutic effects of a combination of two per cent sodium cromoglycate and 0.025 per cent xylometazoline compared with a matched placebo. Forty patients were included in the two-week study.

The treatment was found to be rapidly effective taking only a day to control symptoms in almost 80 per cent of the patients in the group receiving active treatment.

No evidence of rebound effects due to the decongestant was observed during the study.

Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 101 , Issue 7 , July 1987 , pp. 666 - 672
Copyright
Copyright © JLO (1984) Limited 1987

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References

Bende, M., Andersson, K. E., Johannsson, C-J.Sjogren, G. and Svensson, G. (1984) Dose response relationship of a topical nasal decongestant: phenylpropanolamine. Acta Otolaryngologica, 98: 543–547.CrossRefGoogle ScholarPubMed
Frostad, A. B. (1977) The treatment of seasonal allergic rhinitis with 2% aqueous solution of sodium cromoglycate delivered by a metered dose nasal spray. Clinical Allergy, 7: 347–353.CrossRefGoogle ScholarPubMed
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