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Adenoid cystic carcinoma of the sinonasal tract: outcome of endonasal endoscopic surgery at five-year follow up

Published online by Cambridge University Press:  10 April 2013

B S Gendeh ,
F D Zahedi ,
H Ahmad  and
T Y Kew
B S Gendeh*
Affiliation:
Department of Otorhinolaryngology-Head and Neck Surgery, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia
F D Zahedi
Affiliation:
Department of Otorhinolaryngology-Head and Neck Surgery, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia
H Ahmad
Affiliation:
Otorhinolaryngology Department, Putrjaya Hospital, Malaysia
T Y Kew
Affiliation:
Department of Radiology, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia
*
Address for correspondence: Professor Dato’ Dr Balwant Singh Gendeh, Senior Otorhinolaryngologist and Lecturer, Otorhinolaryngology-Head and Neck Surgery Department, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaakob Latif, Bandar Tun Razak, 56000 Cheras, Kuala Lumpur, Malaysia Fax: +60 3 91737840 E-mail: bsgendeh@gmail.com
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Abstract

Objective:

To study the outcome of endonasal endoscopic surgery for adenoid cystic carcinoma of the sinonasal tract over a five-year follow-up period.

Design:

Retrospective analysis.

Methods:

Four consecutive patients with adenoid cystic carcinoma of the sinonasal tract, who had undergone endonasal endoscopic surgery, were reviewed regarding age at diagnosis, sex, primary site, tumour-node-metastasis staging, treatment modalities, histopathological findings, duration of follow up, distant metastases and treatment outcome.

Results:

All patients were diagnosed at an advanced stage and had post-operative adjuvant radiotherapy. Three patients underwent endoscopic endonasal resection and one endoscopic assisted craniofacial resection. The most common primary site was the ethmoid sinus (three patients). Three patients had no evidence of recurrence. One patient who had undergone partial clearance via endoscopic endonasal resection developed cervical node metastases a year after treatment; this patient also developed distant metastases.

Conclusion:

Adenoid cystic carcinoma is difficult to treat. Sinonasal tract tumours can be resected via endoscopic endonasal resection or endoscopic assisted craniofacial resection, but prolonged follow up is advisable. Radiotherapy is an important adjuvant treatment.

Keywords

Nasal CavityParanasal SinusesCarcinoma, Adenoid CysticEndoscopySurgical Procedures, OperativeRadiotherapyNeoplasm Metastasis
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 127 , Issue 5 , May 2013 , pp. 511 - 515
Copyright
Copyright © JLO (1984) Limited 2013 

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