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Adult cystic hygroma: successful use of OK-432 (Picibanil®)

  • S L Woolley (a1), D R K Smith (a2) and S Quine (a2)

We report an adult case of cystic lymphangioma treated with OK-432 (Picibanil®).


A case report and review of the literature concerning the use of OK-432 to treat cystic lymphangioma is presented.


A 31-year-old woman developed a cystic lymphangioma four weeks post-partum. This was treated initially by aspiration, for diagnostic purposes. Investigation suggested that surgery would be challenging. A review of the literature demonstrated success with OK-432 in the treatment of this condition, although primarily in the paediatric population. This patient was successfully treated thus, and at the time of writing remained symptom free. A suggested management plan is outlined.


Treatment with OK-432 is useful in the management of cystic lymphangiomas in adults and should be considered as first line treatment.

Corresponding author
Address for correspondence: Dr Sarah L Woolley, Consultant, Emergency Department, Bristol Royal Infirmary, Upper Maudlin Street, Bristol BS2 8BJ, UK. Fax: +44 117 928 2713 E-mail:
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