Skip to main content
×
Home

Management of inverted papilloma: review

  • B Attlmayr (a1), S G Derbyshire (a1), A V Kasbekar (a1) and A C Swift (a1)
Abstract
Abstract Background:

Inverted papilloma is the most common benign tumour affecting the nose. There is a high rate of recurrence and a potential of malignant transformation. This review article aimed to identify the best available management of this pathology today.

Method:

A systematic review of the current English-language literature was performed. Only original articles with a minimum follow up of one year and an average follow up of two years were included.

Results:

A total of 1385 patients from 16 case series were identified. The total recurrence rate for all patients was 11.5 per cent. Significantly lower recurrence rates were found for procedures using an attachment-oriented excision (recurrence of 6.9 per cent; p = 0.0001) and utilising frozen sections (recurrence of 7.0 per cent; p = 0.0001).

Conclusion:

There is a general trend towards endoscopic surgery. There may be some benefit to the use of attachment-oriented surgery and frozen sections. Multi-centred randomised controlled trials are required.

Copyright
Corresponding author
Address for correspondence: Dr B Attlmayr, ENT Department, Aintree University Hospital, Longmoor Lane, Liverpool L9 7AL, UK Fax: 00 44 151 529 5237 E-mail: bernhard.attlmayr@aintree.nhs.uk
Footnotes
Hide All

Presented as a poster at the 25th Congress of the European Rhinologic Society, 22–26 June 2014, Amsterdam, the Netherlands.

Footnotes
References
Hide All
1 Lund VJ, Stammberger H, Nicolai P, Castelnuovo P, Beal T, Beham A et al. European position paper on endoscopic management of tumours of the nose, paranasal sinuses and skull base. Rhinol Suppl 2010;22:1143
2 Mirza S, Bradley PJ, Acharya A, Stacey M, Jones NS. Sinonasal inverted papillomas: recurrence, and synchronous and metachronous malignancy. J Laryngol Otol 2007;1:857–64
3 Govindaraj S, Wang H. Does human papilloma virus play a role in sinonasal inverted papilloma? Curr Opin Otolaryngol Head Neck Surg 2014;22:4751
4 d'Errico A, Zajacova J, Cacciatore A, Baratti A, Zanelli R, Alfonzo S et al. Occupational risk factors for sinonasal inverted papilloma: a case-control study. Occup Environ Med 2013;70:703–8
5 Lund VJ. Optimum management of inverted papilloma. J Laryngol Otol 2000;114:194–7
6 Lawson W, Kaufman MR, Biller HF. Treatment outcomes in the management of inverted papilloma: an analysis of 160 cases. Laryngoscope 2003;113:1548–56
7 Dragonetti A, Gera R, Sciuto A, Scotti A, Bigoni A, Barbaro E et al. Sinonasal inverted papilloma: 84 patients treated by endoscopy and proposal for a new classification. Rhinology 2011;49:207–13
8 Mackle T, Chambon G, Garrel R, Meieff M, Crampette L. Endoscopic treatment of sinonasal papilloma: a 12 year review. Acta Otolaryngol 2008;128:670–4
9 Waitz G, Wigand ME. Results of endoscopic sinus surgery for the treatment of inverted papillomas. Laryngoscope 1992;102:917–22
10 Tomenzoli D, Castelnuovo P, Pagella F, Berlucchi M, Pianta L, Delù G et al. Different endoscopic surgical strategies in the management of inverted papilloma of the sinonasal tract: experience with 47 patients. Laryngoscope 2004;114:193200
11 Tufano RP, Thaler ER, Lanza DC, Kennedy DW. Endoscopic management of inverted papilloma. Am J Rhinol 1999;13:423–6
12 Landsberg R, Cavel O, Segev Y, Khafif A, Fliss DM. Attachment-oriented endoscopic surgical strategy for sinonasal inverted papilloma. Am J Rhinol 2008;22:629–34
13 Busquets JM, Hwang PH. Endoscopic resection of sinonasal inverted papilloma: a meta-analysis. Otolaryngol Head Neck Surg 2006;134:476–82
14 Karkos PD, Fyrmpas G, Carrie SC, Swift AC. Endoscopic versus open surgical interventions for inverted nasal papilloma: a systematic review. Clin Otolaryngol 2006;31:499503
15 Lombardi D, Tomenzoli D, Buttà L, Bizzoni A, Farina D, Sberze F et al. Limitations and complications of endoscopic surgery for treatment for sinonasal inverted papilloma: a reassessment after 212 cases. Head Neck 2011;33:1154–61
16 Pagella F, Giourgos G, Matti E, Canevari FR, Carena P. Endoscopic treatment of maxillary inverted papilloma. Rhinology 2011;49:369–74
17 Carta F, Blancal JP, Verillaud B, Tran H, Sauvaget E, Kania R et al. Surgical management of inverted papilloma: approaching a new standard for surgery. Head Neck 2013;35:1415–20
18 Krouse JH. Development of a staging system for inverted papilloma. Laryngoscope 2000;110:965–8
19 Oikawa K, Furuta Y, Nakamaru Y, Oridate N, Fukuda S. Preoperative staging and surgical approaches for sinonasal inverted papilloma. Ann Otol Rhinol Laryngol 2007;116:674–80
20 Socher JA, Cassano M, Filheiro CA, Cassano P, Felippu A. Diagnosis and treatment of isolated sphenoid sinus disease: a review of 109 cases. Acta Otolaryngol 2008;128:1004–10
21 Durucu C, Baglam T, Karatas E, Mumbuc S, Kanlikama M. Surgical treatment of inverted papilloma. J Craniofac Surg 2009;20:1985–8
22 Weber RK, Werner JA, Hildenbrand T. Endonasal endoscopic medial maxillectomy with preservation of the inferior turbinate. Am J Rhinol Allergy 2010;24:132–5
23 Liu Q, Yu H, Minovi A, Wei W, Wang D, Zheng C et al. Management of maxillary sinus inverted papilloma via transnasal endoscopic anterior and medial maxillectomy. ORL J Otorhinolaryngol Relat Spec 2010;72:247–51
24 Giotakis E, Eleftheriadou A, Ferekidou E, Kandiloros D, Manolopoulos L, Yiotakis I. Clinical outcomes of sinonasal inverted papilloma surgery. A retrospective study of 67 cases. B-ENT 2010;6:111–16
25 Bathma S, Harvinder S, Philip R, Rosalind S, Gurdeep S. Endoscopic management of sinonasal inverted papilloma. Med J Malaysia 2011;66:1518
26 Kim DY, Hong SL, Lee CH, Jin HR, Kang JM, Lee BJ et al. Inverted papilloma of the nasal cavity and paranasal sinuses: a Korean multicenter study. Laryngoscope 2012;122:487–94
27 Wang C, Han D, Zhang L. Modified endoscopic maxillary medial sinusotomy for sinonasal inverted papilloma with attachment to the anterior medial wall of maxillary sinus. ORL J Otorhinolaryngol Relat Spec 2012;74:97101
28 Lian F, Juan H. Different endoscopic strategies in the management of recurrent sinonasal inverted papilloma. J Craniofac Surg 2012;23:44–8
29 Xiao-Ting W, Peng L, Xiu-Qing W, Hai-Bo W, Wen-Hui P, Bing L et al. Factors affecting recurrence of sinonasal inverted papilloma. Eur Arch Otorhinolaryngol 2013;270:1349–53
30 Sciarretta V, Fernandez IJ, Farneti P, Pasquini E. Endoscopic and combined external-transnasal endoscopic approach for the treatment of inverted papilloma: analysis of 110 cases. Eur Arch Otorhinolaryngol 2013;271:1953–9
31 Sauter A, Matharu R, Hörmann K, Naim R. Current advances in the basic research and clinical management of sinonasal inverted papilloma (review). Oncol Rep 2007;17:495504
32 Rowe DE, Carroll RJ, Day CL Jr. Prognostic factors for local recurrence, metastasis, and survival rates in squamous cell carcinoma of the skin, ear, and lip. Implications for treatment modality selection. J Am Acad Dermatol 1992;26:976–90
33 Syrjänen K, Syrjänen S. Detection of human papillomavirus in sinonasal papillomas: systematic review and meta-analysis. Laryngoscope 2013;123:181–92
34 Philpott CM, Dharamsi A, Witheford M, Javer AR. Endoscopic management of inverted papillomas: long-term results--the St. Paul's Sinus Centre experience. Rhinology 2010;48:358–63
35 Tschopp KP, Thomaser EG. Outcome of functional endonasal sinus surgery with and without CT-navigation. Rhinology 2008;46:116–20
36 Sham CL, Woo JK, van Hasselt CA, Tong MC. Treatment results of sinonasal inverted papilloma: an 18-year study. Am J Rhinol Allergy 2009;23:203–11
37 Kaluskar SK, Mehta R, Farnan TB, Basha SI. Endoscopic 532-nm KTP laser excision of inverted papilloma of the nose and paranasal sinuses: a series of 9 patients. Ear Nose Throat J 2009;88:880–7
38 Hughes OR, Skilbeck CJ, Kwame I, Kwa K, Choa DI. Suction diathermy as an adjunct to endoscopic removal of inverted papilloma. Laryngoscope 2011;121:997–8
39 Syed MI, Mennie J, Williams AT. Early experience of radio frequency coblation in the management of intranasal and sinus tumors. Laryngoscope 2012;122:436–9
40 Zhang Y, Yang Y, Zou X. Efficacy of 5-aminolevulinic acid photodynamic therapy in treatment of nasal inverted papilloma. Photodiagnosis Photodyn Ther 2013;10:549–51
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

The Journal of Laryngology & Otology
  • ISSN: 0022-2151
  • EISSN: 1748-5460
  • URL: /core/journals/journal-of-laryngology-and-otology
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords:

Metrics

Altmetric attention score

Full text views

Total number of HTML views: 8
Total number of PDF views: 135 *
Loading metrics...

Abstract views

Total abstract views: 736 *
Loading metrics...

* Views captured on Cambridge Core between 9th February 2017 - 24th November 2017. This data will be updated every 24 hours.