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Platelet-rich plasma in otolaryngology

  • M Stavrakas (a1), P D Karkos (a1) (a2), K Markou (a1) and N Grigoriadis (a3) (a4)
Abstract
Background:

Platelet-rich plasma is a novel material that is being used more frequently in many surgical specialties.

Methods:

A literature review on the current and potential uses of platelet-rich plasma in otolaryngology was performed.

Results:

There is limited evidence on the use of platelet-rich plasma in otolaryngology compared with other specialties: only 11 studies on various subspecialties (otology, rhinology and laryngology) were included in the final review.

Conclusion:

Based on the limited number of studies, we cannot draw safe conclusions about the value of platelet-rich plasma in otolaryngology. Nevertheless, the available literature suggests that platelet-rich plasma holds promise for future research and may have a number of clinical applications.

Copyright
Corresponding author
Address for correspondence: Mr M Stavrakas, Department of Otolaryngology, AHEPA University Hospital, S. Kiriakidi 1, Thessaloniki 54621, Greece E-mail: mstavrakas@doctors.org.uk
References
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1 Gopalakrishnan, S, Venkatasamy, P, Vivekanandamurthy, K. A study on efficacy of autologous platelet rich plasma in myringoplasty. Online J Otolaryngol 2013;3:3651
2 Sclafani, AP, Azzi, J. Platelet preparations for use in facial rejuvenation and wound healing: a critical review of current literature. Aesthetic Plast Surg 2015;39:495505
3 Pomerantz, J, Dutton, JM. Platelet gel for endoscopic sinus surgery. Ann Otol Rhinol Laryngol 2005;114:699704
4 Rice, DH. Platelet-rich plasma in endoscopic sinus surgery. Ear Nose Throat J 2006;85:516
5 Sidman, JD, Lander, TA, Finkelstein, M. Platelet-rich plasma for pediatric tonsillectomy patients. Laryngoscope 2008;118:1765–7
6 Erkilet, E, Koyuncu, M, Atmaca, S, Yarim, M. Platelet-rich plasma improves healing of tympanic membrane perforations: experimental study. J Laryngol Otol 2009;123:482
7 Cho, HH, Jang, S, Lee, SC, Jeong, HS, Park, JS, Han, JY et al. Effect of neural-induced mesenchymal stem cells and platelet-rich plasma on facial nerve regeneration in an acute nerve injury model. Laryngoscope 2010;120:907–13
8 Navarrete Álvaro, ML, Ortiz, N, Rodriguez, L, Boemo, R, Fuentes, J, Mateo, A et al. Pilot study on the efficiency of the biostimulation with autologous plasma rich in platelet growth factors in otorhinolaryngology: otologic surgery (tympanoplasty type I). ISRN Surg 2011:14
9 Salaheldin, AH, Hussein, A. Effect of platelet-rich plasma on nasal mucociliary clearance after submucous diathermy of inferior turbinate. EJENTAS 2012;13:71–5
10 Friji, M, Gopalakrishnan, S, Verma, S, Parida, P, Mohapatra, D. New regenerative approach to atrophic rhinitis using autologous lipoaspirate transfer and platelet-rich plasma in five patients: our experience. Clin Otolaryngol 2014;39:289–92
11 Woo, SH, Jeong, H-S, Kim, JP, Koh, E-H, Lee, SU, Jin, SM et al. Favorable vocal fold wound healing induced by platelet-rich plasma injection. Clin Exp Otorhinolaryngol 2014;7:4752
12 Cobden, SB, Oztürk, K, Duman, S, Esen, H, Aktan, TM, Avunduk, MC et al. Treatment of acute vocal fold injury with platelet-rich plasma. J Voice 2015; doi: 10.1016/j.jvoice.2015.07.012
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The Journal of Laryngology & Otology
  • ISSN: 0022-2151
  • EISSN: 1748-5460
  • URL: /core/journals/journal-of-laryngology-and-otology
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