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Effects of passive smoking on adult nasal respiratory mucosa

Published online by Cambridge University Press:  08 October 2013

S Elwany ,
Y H Saeed  and
I Talaat
S Elwany*
Affiliation:
Department of Otolaryngology, Alexandria Medical School, Egypt
Y H Saeed
Affiliation:
Department of Otolaryngology, Alexandria Medical School, Egypt
I Talaat
Affiliation:
Department of Pathology, Alexandria Medical School, Egypt
*
Address for correspondence: Dr Samy Elwany, 4 Kfr Abdou St # 605, Alexandria, Egypt E-mail: samy.elwany@alexmed.edu.eg
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Abstract

Objective:

The present study aimed to investigate nasal mucosal changes in response to passive exposure to cigarette smoke.

Study design:

The study included 20 women aged 35–51 years who were scheduled for non-rhinological surgical procedures, and who had at least 10 years' prolonged passive exposure to household cigarette smoke. During surgery, two 1-mm3 biopsies of nasal mucosa were taken from the lower border of the inferior turbinate. Specimens were processed and examined with light and transmission electron microscopy.

Results:

Examination of the nasal mucosa showed several histopathological changes. The severity of structural changes increased with duration of smoke exposure. No allergic or neoplastic changes were seen.

Conclusion:

Passive exposure to cigarette smoke has a deleterious effect on the nasal respiratory mucosa. Prolonged passive smoke exposure may also induce other, significant changes not detected in the present study.

Keywords

Passive SmokingNasal MucosaHistopathology
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 127 , Issue 10 , October 2013 , pp. 977 - 981
Copyright
Copyright © JLO (1984) Limited 2013 

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