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The effects of sodium salicylate on the cochlea of guinea pigs

  • Ellis E. Douek (a1), Hilary C. Dodson (a1) and L. H. Bannister (a1)


Corresponding author

Mr. Ellis Douck, E.N.T. Department, Guy's Hospital, London SE1 9RT.


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Aly, S., Mousa, S., El-Kahky, M., Saleh, A. and El-Mofty, A. (1975) Toxic deafness 1. Histological study of the effects of arsenic, salicylates and quinine on the organ of Corti of guinea pigs. Journal of the Egyptian Medical Association, 58: 144157.
Covell, W. P. (1936) A cytological study of the effects of drugs on the cochlea. Archives of Otolaryngology, 23: 633641.
Covell, W. P. (1938) Effects of drugs on the stria vascularis. Archives of Otolaryngology, 27: 438443.
Crifó, S. (1975) Aspirin ototoxicity in the guinea pig. ORL, 37: 2734.
Dodson, H. C., Bannister, L. H. and Douek, E. E. (1978). Further studies of the effects of continuous white noise of moderate intensity (70–80 dB SPL) on the cochlea in young guinea pigs. Acta Otolaryngologica, 86: 195200.
Dodson, H. C., Bannister, L. H. and Douek, E. E. (1982) The effects of combined gentamicin and white noise on the spiral organ of young guinea pigs: a structural study. Acta Otolaryngologica, 94: 193202.
Eddy, L. B., Morgan, R. J. and Carrey, H. C. (1976) Hearing loss due to combined effects of noise and sodium salicylate. ISA Transactions, 15: 103108.
Evans, E. F. and Borerwe, (1982) Ototoxic effects of salicylates on the responses of single cochlear nerve fibres and on cochlear potentials. British Journal ofAudiology, 16: 101108.
Falbe-Hansen, J. (1941) Clinical and experimental histological studies on effects of salicylate and quinine on the ear. Acta Otolaryngologica, 44: 1216.
Gotlib, I. L. (1957) Morphological changes in cells of the cochlear and vestibular analizers following ingestion of sodium salicylate. Vestnik oto-rino-laringologii, 196: 3135.
Ishii, T., Bernstein, J. M. and Balogh, A. (1967) Distribution of tritium-labelled salicylate in the cochlea. Annals of Otology, Rhinology and Laryngology, 76: 368375.
Kirchner, W. (1881) Uber die Einwirkung von Chinin und Salicylsäure auf das Gehörorgan. Berliner klinische Wochenschrift, 18: 725726.
Myers, E. N. and Bernstein, J. M. (1965) Salicylate ototoxicity: A clinical experimental study. Archives of Otolaryngology, 82: 483493.
Silverstein, H., Bernstein, J. M. and Davies, D. G. (1967) Salicylate ototoxicity. A biochemical and electro-physiological study. Annals of Otology, Rhinology and Laryngology, 76: 118128.
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The Journal of Laryngology & Otology
  • ISSN: 0022-2151
  • EISSN: 1748-5460
  • URL: /core/journals/journal-of-laryngology-and-otology
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