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Evaluation of cardiovascular risks and recovery of idiopathic sudden sensorineural hearing loss in hospitalised patients: comparison between complete and partial sudden sensorineural hearing loss

  • C Haremza (a1), N Klopp-Dutote (a1), V Strunski (a1) and C Page (a1)
Abstract Objective:

To evaluate the presence of cardiovascular risk factors and recovery of idiopathic sudden sensorineural hearing loss in hospitalised patients.


A single-centre retrospective study of 80 patients hospitalised for idiopathic sudden sensorineural hearing loss was conducted over a 6-year period. Mean pure tone hearing thresholds were assessed by pure tone audiometry.


Twenty-three of 80 patients (28.75 per cent) initially had no cardiovascular risk factors. Forty-five patients had hyperlipidaemia, 22 patients had hypertension, 7 patients had diabetes mellitus and 7 patients were obese. No statistically significant difference was observed between patients with complete versus partial sudden sensorineural hearing loss (p = 0.0708) concerning the cardiovascular risk factors. At long-term follow up, the hearing recovery rate was not significantly different between the two groups of patients (p = 0.7541).


The lack of a clear relationship between idiopathic sudden sensorineural hearing loss and cardiovascular risk factors suggests that sudden sensorineural hearing loss has a predominantly multifactorial disease profile regardless of hearing impairment severity.

Corresponding author
Address for correspondence: Dr Cyril Page, Service d'ORL et de chirurgie de la face et du cou, CHU Amiens, Hôpital Sud, 80054 Amiens cedex, France E-mail:
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1 Stachler, RJ, Chandrasekhar, SS, Archer, SM, Rosenfeld, RM, Schwartz, SR, Barrs, DM et al. Clinical practice guideline: sudden hearing loss. Otolaryngol Head Neck Surg 2012;146:S135
2 Lionello, M, Staffieri, C, Breda, S, Turato, C, Giacomelli, L, Magnavita, P et al. Uni- and multivariate models for investigating potential prognostic factors in idiopathic sudden sensorineural hearing loss. Eur Arch Otorhinolaryngol 2015;272:1899–906
3 Schreiber, BE, Agrup, C, Haskard, DO, Luxon, LM. Sudden sensorineural hearing loss. Lancet 2010;375:1203–11
4 Charrier, JB, Tran Ba Huy, P. Idiopathic sudden sensorineural hearing loss: a review [in French]. Ann Otolaryngol Chir Cervicofac 2005;122:317
5 Mom, T, Avan, P, Gilain, L. Idiopathic sudden deafness [in French]. Rev Med Interne 2002;23:292307
6 Huy, PT, Sauvaget, E. Idiopathic sudden sensorineural hearing loss is not an otologic emergency. Otol Neurotol 2005;26:896902
7 Ullrich, D, Aurbach, G, Drobik, C. A prospective study of hyperlipidemia as a pathogenic factor in sudden hearing loss. Eur Arch Otorhinolaryngol 1992;249:273–6
8 Ballesteros, F, Alobid, I, Tassies, D, Reverter, JC, Scharf, RE, Guilemany, JM et al. Is there an overlap between sudden neurosensorial hearing loss and cardiovascular risk factors? Audiol Neurotol 2009;14:139–45
9 Rudack, C, Langer, C, Stoll, W, Rust, S, Walter, M. Vascular risk factors in sudden hearing loss. Thromb Haemost 2006;95:454–61
10 Aimoni, C, Bianchini, C, Borin, M, Ciorba, A, Fellin, R, Martini, A et al. Diabetes, cardiovascular risk factors and idiopathic sudden sensorineural hearing loss: a case-control study. Audiol Neurotol 2010;15:111–15
11 Ciccone, MM, Cortese, F, Pinto, M, Di Teo, C, Fornarelli, F, Gesualdo, M et al. Endothelial function and cardiovascular risk in patients with idiopathic sudden sensorineural hearing loss. Atherosclerosis 2012;225:511–16
12 Teranishi, M, Katayama, N, Uchida, Y, Tominaga, M, Nakashima, T. Thirty-year trends in sudden deafness from four nationwide epidemiological surveys in Japan. Acta Otolaryngol 2007;127:1259–65
13 Lin, H-C, Chao, P-Z, Lee, H-C. Sudden sensorineural hearing loss increases the risk of stroke: a 5-year follow-up study. Stroke 2008;39:2744–8
14 Nishio, N, Teranishi, M, Uchida, Y, Sugiura, S, Ando, F, Shimokata, H et al. Contribution of complement factor H Y402H polymorphism to sudden sensorineural hearing loss risk and possible interaction with diabetes. Gene 2012;499:226–30
15 Rust, KR, Prazma, J, Triana, RJ, Michaelis, OE 4th, Pillsbury, HC. Inner ear damage secondary to diabetes mellitus: II. Changes in aging SHR/N-cp rats. Arch Otolaryngol Neck Surg 1992;118:397400
16 Weng, SF, Chen, Y-S, Hsu, CJ, Tseng, FY. Clinical features of sudden sensorineural hearing loss in diabetic patients. Laryngoscope 2005;115:1676–80
17 Fukui, M, Kitagawa, Y, Nakamura, N, Kadono, M, Mogami, S, Ohnishi, M et al. Idiopathic sudden hearing loss in patients with type 2 diabetes. Diabetes Res Clin Pract 2004;63:205–11
18 Perk, J, De Backer, G, Gohlke, H, Graham, I, Reiner, Z, Verschuren, WM et al. European Guidelines on Cardiovascular Disease Prevention in Clinical Practice (version 2012). The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts). Atherosclerosis 2012;223:168
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The Journal of Laryngology & Otology
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  • EISSN: 1748-5460
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