Skip to main content

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
Cancel
×
×
Home
  • Home
Article
  • Cited by 3
  • Cited by
    Crossref Citations
    Crossref logo
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.
    KOJIMA, Taku MIKAMI, Toshihiko HAYASHI, Takafumi MARUYAMA, Satoshi YAMAZAKI, Manabu and KOBAYASHI, Tadaharu 2017. A case of small cell carcinoma arising in the palatine gland. Japanese Journal of Oral and Maxillofacial Surgery, Vol. 63, Issue. 7, p. 358.
    Sehgal, Inderpaul Singh Kaur, Harpreet Dhooria, Sahajal Bal, Amanjit Gupta, Nalini Behera, Digambar and Singh, Navneet 2016. Extrapulmonary small cell carcinoma of lymph node: Pooled analysis of all reported cases. World Journal of Clinical Oncology, Vol. 7, Issue. 3, p. 308.
    Hosokawa, Seiji Takahashi, Goro Baba, Satoshi and Mineta, Hiroyuki 2016. Small Cell Neuroendocrine Carcinomas Arising in the Head and Neck Region. Journal of Oral and Maxillofacial Surgery, Vol. 74, Issue. 5, p. 1091.
    ×
  • Get access
    Add to cart USD35.00
    Check if you have access via personal or institutional login
    Log in Register Recommend to librarian

Extrapulmonary small cell carcinoma in head and neck

  • R Yasumatsu (a1), T Nakashima (a1), M Yamauchi (a1), S Toh (a1) and S Komune (a1)...
Abstract
Purpose:

The management of extrapulmonary small cell carcinoma has not been standardised to date. This study reviewed the clinical course, management and survival outcomes of patients with extrapulmonary small cell carcinoma in the head and neck region.

Methods:

Nine patients with extrapulmonary small cell carcinoma in the head and neck were included in this study.

Results:

Five patients received radical surgery followed by adjuvant chemotherapy or radiotherapy or both. Two other patients were treated with chemotherapy consisting of CPT11 plus cisplatin or CPT11 plus cisplatin plus VP-16 three times. Two other patients received chemoradiotherapy consisting of S-1 or CPT11 plus cisplatin. The median overall survival was 14.5 months, with a three-year survival rate of 23.7 per cent.

Conclusions:

The prognosis of extrapulmonary small cell carcinoma is generally poor. Further prospective multicentre studies are required for better understanding of disease entities and response to treatment modalities.

Copyright
COPYRIGHT: © JLO (1984) Limited 2015 
Corresponding author
Address for correspondence: Ryuji Yasumatsu, Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan Fax: + 81926425685 E-mail: yasuryuj@qent.med.kyushu-u.ac.jp
References
Hide All
1van der Heijden, HF, Heijdra, YF. Extrapulmonary small cell carcinoma. South Med J 2005;98:345–9
2Walenkamp, AM, Sonke, GS, Sleijfer, DT. Clinical and therapeutic aspects of extrapulmonary small cell carcinoma. Cancer Treat Rev 2009;35:228–36
3Ferlito, A. Diagnosis and treatment of small cell carcinoma of the larynx: a critical review. Ann Otol Rhinol Laryngol 1986;95:590–600
4Remick, SC, Ruckdeschel, JC. Extrapulmonary and pulmonary small-cell carcinoma: tumor biology, therapy, and outcome. Med Pediatr Oncol 1992;20:89–99
5Lo Re, G, Canzonieri, V, Veronesi, A, Dal Bo, V, Barzan, L, Zancanaro, C, et al. Extrapulmonary small cell carcinoma: a single-institution experience and review of the literature. Ann Oncol 1994;5:909–13
6Brennan, SM, Gregory, DL, Stillie, A, Herschtal, A, Mac Manus, M, Ball, DL. Should extrapulmonary small cell cancer be managed like small cell lung cancer? Cancer 2010;116:888–895
7Cicin, I, Karagol, H, Uzunoglu, S, Uygun, K, Usta, U, Kocak, Z et al. Extrapulmonary small-cell carcinoma compared with small-cell lung carcinoma: a retrospective single-center study. Cancer 2007;110:1068–76
8Weng, CT, Chu, PY, Liu, MT, Chen, MK. Small cell carcinoma of the head and neck: a single institution's experience and review of the literature. J Otolaryngol Head Neck Surg 2008;37:788–793
9Haider, K, Shahid, RK, Finch, D, Sami, A, Ahmad, I, Yadav, S et al. Extrapulmonary small cell cancer: a Canadian province's experience. Cancer 2006;107:2262–9
10Grossman, RA, Pedroso, FE, Byrne, MM, Koniaris, LG, Misra, S. Does surgery or radiation therapy impact survival for patients with extrapulmonary small cell cancers? J Surg Oncol 2011; 104:604–12
11Weiss, MD, deFries, HO, Taxy, JB, Braine, H. Primary small cell carcinoma of the paranasal sinuses. Arch Otolaryngol 1983;109:341–3
12Kim, KO, Lee, HY, Chun, SH, Shin, SJ, Kim, MK, Lee, KH et al. Clinical overview of extrapulmonary small cell carcinoma. J Korean Med Sci 2006;21:833–7
13Ochsenreither, S, Marnitz-Schultze, S, Schneider, A, Koehler, C, Daum, S, Loddenkemper, C et al. Extrapulmonary small cell carcinoma (EPSCC): 10 years' multi-disciplinary experience at Charite. Anticancer Res 2009;29:3411–15
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

The Journal of Laryngology & Otology
  • ISSN: 0022-2151
  • EISSN: 1748-5460
  • URL: /core/journals/journal-of-laryngology-and-otology
Please enter your name
Please enter a valid email address
Who would you like to send this to? *

CAPTCHA *

Skip to the audio challenge
×

Keywords:

Metrics

Full text views

Total number of HTML views: 2
Total number of PDF views: 33 *
Loading metrics...

Abstract views

Total abstract views: 280 *
Loading metrics...

* Views captured on Cambridge Core between September 2016 - 13th June 2018. This data will be updated every 24 hours.

Cancel
Confirm
×