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Facial nerve schwannoma: nerve fibre dissemination

Published online by Cambridge University Press:  29 June 2007

Mutawakel Hajjaj  and
Fred H. Linthicum Jr
Mutawakel Hajjaj
Affiliation:
Senior Registrar, Choud Hospital, Medina, Saudi Arabia
Fred H. Linthicum Jr*
Affiliation:
Head, Department of Histopathology, House Ear Institute, Los Angeles, USA
*
Address for correspondence: Fred H. Linthicum Jr., M.D., House Ear Institute, 2100 West Third Street, Los Angeles, California 90057, USA. Fax: (213) 413-6739.
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Abstract

Biopsy of a middle ear mass can lead to facial paralysis when the mass is a facial nerve schwannoma. Immunostaining techniques were used to determine if nerve fibres might be present within the tumour mass. Nerve fibres were found to be widely disseminated throughout the tumour in eight of 23 facial nerve schwannomas. Antibodies to neurofilaments demonstrated single fibres, or small groups of fibres, that are very difficult to see with routine haematoxylin and eosin stains. The presence of fibres throughout some tumours makes biopsy of them likely to result in facial dysfunction.

Keywords

Facial nerve schwannomaFacial paralysisImmunohistochemistry
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 110 , Issue 7 , July 1996 , pp. 632 - 633
Copyright
Copyright © JLO (1984) Limited 1996

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