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Is hyperbaric oxygen therapy a salvage treatment option for sudden sensorineural hearing loss?

  • Y Alimoglu (a1) and E Inci (a2)
Abstract Objective:

To investigate of the efficacy of hyperbaric oxygen therapy as a salvage treatment after unsuccessful oral corticosteroid therapy.


Case notes of patients who were followed up because of idiopathic sudden sensorineural hearing loss between 2005 and 2011 in a tertiary care centre were examined retrospectively. Audiograms from before and after hyperbaric oxygen therapy were examined in terms of mean gains in pure tone average and at 0.25, 0.5, 1, 2, 4 and 8 kHz. In addition, recovery according to Siegel's criteria was noted.


Mean gain in pure tone average was 10.55 ± 13.56 dB. Mean gains at 0.25, 0.5, 1, 2, 4 and 8 kHz were 16.66 ± 18.43 dB, 16.94 ± 19.93 dB, 12.63 ± 16.71 dB, 7.36 ± 15.28 dB, 5.27 ± 11.58 dB and 2.91 ± 12.44 dB, respectively. Three patients had complete recovery, 1 had partial recovery, 5 had slight recovery and 25 had no improvement.


Hyperbaric oxygen utilised as a salvage therapy after failed corticosteroid therapy may be beneficial in some patients. Studies with more patients are needed.

Corresponding author
Address for correspondence: Dr Yalcin Alimoglu, Haseki Egitim ve Arastirma Hastanesi, Kulak Burun Bogaz Klinigi, Fatih, İstanbul, Turkey E-mail:
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2 DE Mattox , FB Simmons . Natural history of sudden sensorineural hearing loss. Ann Otol Rhinol Laryngol 1977;86:463–80

4 FM Byl Jr. Sudden hearing loss: 8 years’ experience and suggested prognostic table. Laryngoscope 1984;94:647–61

5 Y Alimoglu , E Inci , DT Edizer , A Ozdilek , M Aslan . Efficacy comparison of oral steroid, intratympanic steroid, hyperbaric oxygen and oral steroid + hyperbaric oxygen treatments in idiopathic sudden sensorineural hearing loss cases. Eur Arch Otorhinolaryngol 2011;268:1735–41

7 B Mazurek , H Haupt , P Georgiewa , BF Klapp , A Reisshauer . A model of peripherally developing hearing loss and tinnitus based on the role of hypoxia and ischemia. Med Hypotheses 2006;67:892–9

8 MH Bennett , T Kertesz , P Yeung . Hyperbaric oxygen for idiopathic sudden sensorineural hearing loss and tinnitus. Cochrane Database Syst Rev 2007;(1):CD004739

9 K Nagahara , U Fisch , N Yagi . Perilymph oxygenation in sudden and progressive sensorineural hearing loss. Acta Otolaryngol 1983;96:5768

10 T Kubo , T Matsunaga , H Asai , K Kawamoto , J Kusakari , Y Nomura Efficacy of defibrinogenation and steroid therapies on sudden deafness. Arch Otolaryngol Head Neck Surg 1988;114:649–52

11 E Muzzi , B Zennaro , R Visentin , F Soldano , C Sacilotto . Hyperbaric oxygen therapy as salvage treatment for sudden sensorineural hearing loss: review of rationale and preliminary report. J Laryngol Otol 2010;124:e2

12 CE Horn , HN Himel , SH Selesnick . Hyperbaric oxygen therapy for sudden sensorineural hearing loss: a prospective trial of patients failing steroid and antiviral treatment. Otol Neurotol 2005;26:882–9

13 L Cvorovic , MB Jovanovic , Z Milutinovic , N Arsovic , D Djeric . Randomized prospective trial of hyperbaric oxygen therapy and intratympanic steroid injection as salvage treatment of sudden sensorineural hearing loss. Otol Neurotol 2013;34:1021–6

14 CH Yang , RW Wu , CF Hwang . Comparison of intratympanic steroid injection, hyperbaric oxygen and combination therapy in refractory sudden sensorineural hearing loss. Otol Neurotol 2013;34:1411–16

16 M Pezzoli , M Magnano , L Maffi , L Pezzoli , P Marcato , M Orione Hyperbaric oxygen therapy as salvage treatment for sudden sensorineural hearing loss: a prospective controlled study. Eur Arch Otorhinolaryngol 2015;272:1659–66

17 RJ Stachler , SS Chandrasekhar , SM Archer , RM Rosenfeld , SR Schwartz , DM Barrs Clinical practice guideline: sudden hearing loss. Otolaryngol Head Neck Surg 2012;146:S135

18 SW Yeo , DH Lee , BC Jun , SY Park , YS Park . Hearing outcome of sudden sensorineural hearing loss: long-term follow-up. Otolaryngol Head Neck Surg 2007;136:221–4

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The Journal of Laryngology & Otology
  • ISSN: 0022-2151
  • EISSN: 1748-5460
  • URL: /core/journals/journal-of-laryngology-and-otology
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