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Juvenile nasopharyngeal angiofibroma: a single centre's 11-year experience

Published online by Cambridge University Press:  22 October 2018

A E Pamuk ,
S Özer ,
A E Süslü ,
A Akgöz  and
M Önerci
A E Pamuk*
Affiliation:
Department of Otorhinolaryngology, Akyurt State Hospital, Ankara, Turkey
S Özer
Affiliation:
Department of Otorhinolaryngology, Faculty of Medicine, Hacettepe University, Ankara, Turkey
A E Süslü
Affiliation:
Department of Otorhinolaryngology, Faculty of Medicine, Hacettepe University, Ankara, Turkey
A Akgöz
Affiliation:
Department of Radiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey
M Önerci
Affiliation:
Department of Otorhinolaryngology, Faculty of Medicine, Hacettepe University, Ankara, Turkey
*
Author for correspondence: Dr Ahmet Erim Pamuk, Department of Otorhinolaryngology, Akyurt State Hospital, 06750 Akyurt – Ankara, Turkey E-mail: dr_erim@hotmail.com Fax: +90 312 844 3016
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Abstract

Objective

This study aimed to present the clinical features and surgical outcomes of juvenile nasopharyngeal angiofibroma patients who were surgically treated.

Methods

The medical records of 48 male patients histologically confirmed as having juvenile nasopharyngeal angiofibroma, who underwent transnasal endoscopic surgery between 2005 and 2016, were retrospectively reviewed.

Results

The overall recurrence rate was 20.8 per cent; however, the recurrence rate differed significantly between patients diagnosed aged less than 14 years (34.7 per cent) and more than 14 years (8 per cent) (p < 0.05). Advanced-stage tumours (Radkowski stage of IIC or more, and Önerci stage of III or more) were more aggressive than earlier stage tumours (p < 0.05 and p < 0.01, respectively). Pre-operative embolisation significantly prolonged mean hospitalisation duration, but had no effect on intra-operative blood loss in patients with advanced-stage tumours (p < 0.001 and p = 0.09, respectively).

Conclusion

The findings show that transnasal endoscopic surgery could be considered the treatment of choice for juvenile nasopharyngeal angiofibroma. Patients diagnosed when aged less than 14 years and those with advanced-stage tumours are at risk of recurrence, and should be monitored with extreme care.

Keywords

AngiofibromaNasopharynxEndoscopyNasal Surgical ProceduresEmbolizationTherapeutic
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 132 , Issue 11 , November 2018 , pp. 978 - 983
Copyright
Copyright © JLO (1984) Limited, 2018 

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Footnotes

Dr A E Pamuk takes responsibility for the integrity of the content of the paper

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