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Melanotic neuroectodermal tumour of infancy arising in the maxilla

  • Ahmed el-Saggan (a1), Gisle Bang (a2) and Jan Olofsson (a1)
Abstract

Melanotic neuroectodermal tumour of infancy is an uncommon neoplasm that usually occurs in children aged one year or less. Difficulty in deciding the cellular origin of this tumour has led to numerous names, including congenital melanocarcinoma, melanotic epithelial odontoma, melanotic ameloblastoma, and retinal anlage tumour. Electron microscopy and histochemical studies, however, have now established the neural crest origin. The most frequent site of occurrence is the maxilla followed by the skull, the brain and the mandible. The genital organs are the most frequent extracranial site.

We present two cases of melanotic neuroectodermal tumour of infancy arising in the maxilla.

Copyright
COPYRIGHT: © JLO (1984) Limited 1998
Corresponding author
Address for corespondence: Dr A. el-Saggan, Department of Otolaryngology/Head and Neck Surgery, Haukeland University Hospital, N-5021 Bergen, Norway. Fax: -47-55 97 49 56
References
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Borello, E. D., Gorlin, R. J. (1966) Melanotic neuroectodermal tumour of infancy - a neoplasm of neural crest origin. Report of a case associated with a high urinary excretion of vanilmandelic acid. Cancer 19: 196–206.
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Nagase, M., Udea, K., Fukushima, M., Nakajima, T. (1983) Recurrent melanotic neuroectodermal tumour of infancy. Case report and survey of 16 cases. Journal of Maxillofacial Surgery 11: 131–136.
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The Journal of Laryngology & Otology
  • ISSN: 0022-2151
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