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Non-hodgkin's lymphoma of the tonsil

Experience of treatment over a 27-year period

Published online by Cambridge University Press:  29 June 2007

A. R. Makepeace ,
D. C. Fermont  and
M. H. Bennett
A. R. Makepeace*
Affiliation:
Senior Registrar, The Meyerstein Institue of Radiotheraphy and Oncology, The Middlesex Hospistal, Mortimer Street, London WI.
D. C. Fermont
Affiliation:
Consultant in Radiotherapy and Oncology, Mount Vernon Hospital, Northwood, Middlesex.
M. H. Bennett
Affiliation:
Consultant Histopathologist, Mount Vernon Hospital, Northwood, Middlesex.
*
A. R. Makepeace, F.R.C.R., Senior Registrar, Meyerstein Institute of Radiotherapy and Oncology, The Middlesex Hospital, London WIN 8AA.
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Abstract

Over the 27-year period from 1954–1981, 51 patients with non-Hodgkin's lymphoma arising in the tonsil were treated at the Regional Radiotherapy Centre, Mount Vernon Hospital. The original biopsy material was reviewed in each case and reclassified using the British National Lymphoma Investigation criteria. Grade 2 non-Hodgkin's lymphoma was reported in 80 per cent of cases. Ninety per cent of patients presented in stages IE or HE and were treated with radical local radiotherapy. A 5-year survival of 51 per cent was achieved and a 5-year relapse-free survival of 35 per cent. Stage IE patients had a statistically significant survival advantage compared to stage HE. Sixty-one per cent of patients relapsed, of whom 74 per cent died from active lymphoma. The abdomen was the most frequent site for relapse with involvement of both nodal and extranodal sites.

Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 101 , Issue 11 , November 1987 , pp. 1151 - 1158
Copyright
Copyright © JLO (1984) Limited 1987

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