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Outcomes of definitive radiotherapy for early laryngeal cancer in terms of survival and patterns of failure

  • M Adeel (a1), M Faisal (a1), A Rashid (a2), S Rasheed (a2), R Hussain (a1), K I Malik (a1), M Y Hameed (a3) and A Jamshed (a2)...

Abstract

Background

Early laryngeal cancer treated with definitive radiotherapy or surgery has a high cure rate. This study evaluated the patterns of treatment failure and long-term results of early laryngeal cancers treated with definitive radiotherapy.

Method

From January 2002 to December 2014, a total of 242 patients with early-stage laryngeal cancers were treated with radical radiotherapy.

Results

All patients had squamous cell carcinoma of the larynx (92 per cent male and 8 per cent female). Median follow-up was 4.5 years. The majority of patients were smokers (57.4 per cent). Local failure was seen in 12.5 per cent of stage I patients and 22.8 per cent of stage II patients. The 5-year overall survival and disease specific survival were 84 per cent and 91 per cent, respectively.

Conclusion

In summary, radiotherapy is a suitable treatment modality for patients with early-stage laryngeal cancer, with an overall locoregional control rate of 84 per cent. Patients who fail radiotherapy may still undergo salvage laryngectomy.

Copyright

Corresponding author

Author for correspondence: Dr Muhammad Faisal, Institute of Head and Neck Disease, Evangelisches Krankenhaus, Hans Sachs Gasse 10-12, Vienna1180, Austria E-mail: maxfas@live.com

Footnotes

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Dr M Faisal takes responsibility for the integrity of the content of the paper

Footnotes

References

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Keywords

Outcomes of definitive radiotherapy for early laryngeal cancer in terms of survival and patterns of failure

  • M Adeel (a1), M Faisal (a1), A Rashid (a2), S Rasheed (a2), R Hussain (a1), K I Malik (a1), M Y Hameed (a3) and A Jamshed (a2)...

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