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    Carlson, Matthew L. Sweeney, Alex D. Modest, Mara C. Van Gompel, Jamie J. Haynes, David S. and Neff, Brian A. 2015. Inverting papilloma of the temporal bone: Report of four new cases and systematic review of the literature. The Laryngoscope, Vol. 125, Issue. 11, p. 2576.

    Zhang, Si‑Cong Wei, Lin Zhou, Shui‑Hong and Zhao, Kui 2015. Inability of PET/CT to identify a primary sinonasal inverted papilloma with squamous cell carcinoma in a patient with a submandibular lymph node metastasis: A case report. Oncology Letters,

    Mathew Pc, and Idiculla, J.J. 2012. Malignant sinonasal papilloma with neck metastasis: a rare report and literature review. International Journal of Oral and Maxillofacial Surgery, Vol. 41, Issue. 3, p. 368.

    Inoue, Rika Kanazawa, Takeharu Morita, Mamoru Iino, Yukiko Yamada, Shigeki and Ishida, Takashi 2011. Inverted Papilloma of the Middle Ear. Otology & Neurotology, Vol. 32, Issue. 1, p. e7.

    Shen, Jasper Baik, Fred Mafee, Mahmood F. Peterson, Michael and Nguyen, Quyen T. 2011. Inverting Papilloma of the Temporal Bone. Otology & Neurotology, Vol. 32, Issue. 7, p. 1124.

    Anari, S and Carrie, S 2010. Sinonasal inverted papilloma: narrative review. The Journal of Laryngology & Otology, Vol. 124, Issue. 07, p. 705.


Sinonasal inverted papilloma with malignant transformation in the middle ear: a multicentric origin?

  • S Mazlina (a1), M A R Megat Shiraz (a1), M Y S Hazim (a1), A R Amran (a2), A N Zulkarnaen (a3) and W M Wan Muhaizan (a3)
  • DOI:
  • Published online: 04 May 2006

Inverted papilloma is a rare, benign tumour representing only 0.5 to 4 per cent of all sinonasal neoplasms; its involvement of the middle ear is extremely rare. We present a case of multicentric inverted papilloma in the sinonasal region and middle ear in a 54-year-old man. The patient later developed neck metastasis secondary to malignant transformation of the inverted papilloma in the middle ear.

Corresponding author
Address for correspondence: Dr Mazlina Bt Selamat, Department of Otorhinolaryngology – Head & Neck Surgery, Faculty of Medicine, UKM Hospital, Jalan Yaacob Latif, 56000 Kuala Lumpur, Malaysia. Fax: +603 91737840 E-mail:
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The Journal of Laryngology & Otology
  • ISSN: 0022-2151
  • EISSN: 1748-5460
  • URL: /core/journals/journal-of-laryngology-and-otology
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