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Sinonasal inverted papilloma with malignant transformation in the middle ear: a multicentric origin?

  • S Mazlina (a1), M A R Megat Shiraz (a1), M Y S Hazim (a1), A R Amran (a2), A N Zulkarnaen (a3) and W M Wan Muhaizan (a3)...

Inverted papilloma is a rare, benign tumour representing only 0.5 to 4 per cent of all sinonasal neoplasms; its involvement of the middle ear is extremely rare. We present a case of multicentric inverted papilloma in the sinonasal region and middle ear in a 54-year-old man. The patient later developed neck metastasis secondary to malignant transformation of the inverted papilloma in the middle ear.

Corresponding author
Address for correspondence: Dr Mazlina Bt Selamat, Department of Otorhinolaryngology – Head & Neck Surgery, Faculty of Medicine, UKM Hospital, Jalan Yaacob Latif, 56000 Kuala Lumpur, Malaysia. Fax: +603 91737840 E-mail:
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The Journal of Laryngology & Otology
  • ISSN: 0022-2151
  • EISSN: 1748-5460
  • URL: /core/journals/journal-of-laryngology-and-otology
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