Skip to main content Accessibility help

Soft tissue reaction to ceramic ossicular replacement prosthesis

  • Etsuo Yamamoto (a1) and Michitaka Iwanaga (a1)


Soft-tissue reaction to ceramic ossicular replacement prostheses (CORP) has been evaluated histologically in rabbits and humans. One week after implantation, severe inflammatory and foreign body reaction was observed in the fibrous connective tissue surrounding the prosthesis. Though some inflammatory response was seen after one month, after three months the CORP was surrounded by a layer of fibrous connective tissue without any foreigh body giant cell, histiocyte or inflammatory cell infiltration. Our satisfactory clinical results in humans without placing a cartilage between the CORP and the fascia graft may be due to the excellent softtissue compatibility of CORP, as demonstrated in this study.


Corresponding author

Department of Otolaryngology, Faculty of Medicine, Kyoto University, Sakyo-ku, Kyoto, 606Japan.


Hide All
Belal, A., and Odnert, M. S. (1982) Torps and Porps: A transmission and scanning electron microscopic study. Journal of Laryngology and Otology, 96: 4955.
Frootko, N. J. (1984) Failed ossiculoplasty using porous polyethylene (Plasti-pore®) Prostheses. Journal of Laryngology and Otology, 98: 121126.
Jahnke, K., and Plester, D. (1980) Keramik-Implan-tate in der Mittelohrchirurgie. HNO, 28: 109114.
Kerr, A. G. (1981) Proplast and Plastipore. Clinical Otolaryngology, 6: 187191.
Reck, R. (1981) Tissue reactions to glass ceramics in the middle ear. Clinical Otolaryngology, 6: 6365.
Yamamoto, E. (1985) Aluminium oxide ceramic ossicular replacement prosthesis. Annals of Otology, Rhinology and Laryngology, 94: 149152.
Yamamoto, E. and Iwanaga, M. (1985) Ossiculoplasty failure with ceramic ossicular replacement prosthesis. O.R.L. 48: 332337.
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

The Journal of Laryngology & Otology
  • ISSN: 0022-2151
  • EISSN: 1748-5460
  • URL: /core/journals/journal-of-laryngology-and-otology
Please enter your name
Please enter a valid email address
Who would you like to send this to? *


Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed