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Superficial versus total parotidectomy for metastatic cutaneous squamous cell carcinoma and melanoma of the head and neck: a systematic review

Published online by Cambridge University Press:  01 August 2022

W S Leong Open the ORCID record for W S Leong [Opens in a new window] ,
S Gowda ,
R Jackson Open the ORCID record for R Jackson [Opens in a new window] ,
E Chabrillac  and
O Edafe
W S Leong*
Affiliation:
ENT Department, Doncaster Royal Infirmary, Doncaster, UK
S Gowda
Affiliation:
ENT Department, Sheffield Teaching Hospitals Foundation Trust, UK
R Jackson
Affiliation:
ENT Department, Doncaster Royal Infirmary, Doncaster, UK
E Chabrillac
Affiliation:
Department of Surgery, University Cancer Institute of Toulouse – Oncopole, France
O Edafe
Affiliation:
Oncology and Metabolism, University of Sheffield, UK
*
Author for correspondence: Dr W S Leong, ENT Department, Doncaster Royal Infirmary, Thorne Road, Doncaster DN2 5LT, UK E-mail: wei.leong1@nhs.net
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Abstract

Objective

The extent of parotidectomy in the management of regional metastatic disease is controversial. This systematic review aimed to appraise data from studies evaluating superficial and total parotidectomy in metastatic cutaneous squamous cell carcinoma and cutaneous malignant melanoma of the head and neck.

Method

A systematic search of PubMed, Embase and Cochrane Library was performed. The protocol was registered with Prospero (CRD42020217962).

Results

A total of five studies evaluated cutaneous malignant melanoma. Only one compared outcomes of superficial and total parotidectomy: they found higher parotid area recurrence following superficial parotidectomy. Seven studies reported outcomes following cutaneous squamous cell carcinoma; some studies found higher regional recurrence and reduced survival in total parotidectomy, but there was likely selection bias in these studies. Others found no difference in survival between superficial and total parotidectomy.

Conclusion

The effect of the extent of parotidectomy on outcomes is unclear in cutaneous malignant melanoma and cutaneous squamous cell carcinoma. This systematic review highlights the need for well-designed studies to direct better care.

Keywords

Parotid GlandSquamous Cell CarcinomaMelanomaParotid Cancer
Type
Review Article
Information
The Journal of Laryngology & Otology , Volume 137 , Issue 6 , June 2023 , pp. 592 - 598
Copyright
Copyright © The Author(s), 2022. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED

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Footnotes

Dr W S Leong takes responsibility for the integrity of the content of the paper

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