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Wegener's granulomatosis presenting as a temporal headache

Published online by Cambridge University Press:  29 June 2007

Z. G. G. Makura
Affiliation:
Departments of Otolaryngology/Head and Neck Surgery, City Hospitals, Sunderland, UK and Dunedin Public Hospital, New Zealand
A. K. Robson*
Affiliation:
Departments of Otolaryngology/Head and Neck Surgery, City Hospitals, Sunderland, UK and Dunedin Public Hospital, New Zealand
*
Address for correspondence: Mr A. K. Robson, F.R.C.S., Department of Otolaryngology, City General Hospital, Carlisle CAl 2HG.

Abstract

Formerly a fatal condition, Wegener's granulomatosis is now treated with good results. Clinical morbidity is often due to failure by clinicians to make the diagnosis. Many patients (including our cases reported here) present with atypical symptoms, and only a high index of suspicion will ensure early diagnosis. Classical chest and renal symptoms often indicate late stage disease. We present two cases that underline the limitations of current ‘diagnostic’ immunological tests whilst emphasising the importance of clinical features in diagnosis.

Standard treatment with Cytotoxic agents and corticosteroids are effective but carry considerable morbidity. We have followed the current trend of incorporating a less toxic antibiotic agent in the management of this enigmatic condition.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 1996

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