Bourneville has only seen four cases of disseminated sclerosis in children at Bicètre between 1879 and 1899. These notes refer to one of them. The family history was bad. The patient had an illness with convulsions at the age of three years which was thought to be meningitis; it was followed by loss of speech, which returned after four months, but was stuttering; weakness of the limbs more marked on the right side, which improved gradually in two months; tremors of hands and head; right squint, nystagmus, cephalalgia, and diminution of intelligence. Between the age of four and nine years the condition was practically unaltered. In 1882, when the child was in his tenth year, attacks of vertigo and wanderings occurred, and a few months later, after a great fright, epileptiform seizures. An analysis of the symptoms, the characteristic intention tremors, the paresis, the gait, the cephalic symptoms (amblyopia, diplopia, nystagmus, cephalalgia, affection of speech), the epileptiform attacks, etc., leads Bourneville to the conclusion that the case is a fairly typical one of early cerebro-spinal disseminated sclerosis.
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