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1.E Biagi , M Candela , S Fairweather-Tait , (2012) Aging of the human metaorganism: the microbial counterpart. Age (Dordr) 34, 247–267.
2.MJ Hopkins , R Sharp & GT Macfarlane (2001) Age and disease related changes in intestinal bacterial populations assessed by cell culture, 16S rRNA abundance, and community cellular fatty acid profiles. Gut 48, 198–205.
3.E Biagi , L Nylund , M Candela , (2010) Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians. PLoS ONE 5, e10667.
4.MJ Claesson , S Cusack , O O'Sullivan , (2011) Composition, variability, and temporal stability of the intestinal microbiota of the elderly. Proc Natl Acad Sci U S A 108, Suppl. 1, 4586–4591.
5.S Mueller , K Saunier , C Hanisch , (2006) Differences in fecal microbiota in different European study populations in relation to age, gender, and country: a cross-sectional study. Appl Environ Microbiol 72, 1027–1033.
6.M Rajilic-Stojanovic , HG Heilig , D Molenaar , (2009) Development and application of the human intestinal tract chip, a phylogenetic microarray: analysis of universally conserved phylotypes in the abundant microbiota of young and elderly adults. Environ Microbiol 11, 1736–1751.
8.EJ Woodmansey , ME McMurdo , GT Macfarlane , (2004) Comparison of compositions and metabolic activities of fecal microbiotas in young adults and in antibiotic-treated and non-antibiotic-treated elderly subjects. Appl Environ Microbiol 70, 6113–6122.
9.D Mariat , O Firmesse , F Levenez , (2009) The Firmicutes/Bacteroidetes ratio of the human microbiota changes with age. BMC Microbiol 9, 123.
10.K Fujihashi & H Kiyono (2009) Mucosal immunosenescence: new developments and vaccines to control infectious diseases. Trends Immunol 30, 334–343.
11.AC Shaw , S Joshi , H Greenwood , (2010) Aging of the innate immune system. Curr Opin Immunol 22, 507–513.
12.AC Shaw , A Panda , SR Joshi , (2011) Dysregulation of human Toll-like receptor function in aging. Ageing Res Rev 10, 346–353.
15.RA Rastall , GR Gibson , HS Gill , (2005) Modulation of the microbial ecology of the human colon by probiotics, prebiotics and synbiotics to enhance human health: an overview of enabling science and potential applications. FEMS Microbiol Ecol 52, 145–152.
16.K Tiihonen , AC Ouwehand & N Rautonen (2010) Human intestinal microbiota and healthy ageing. Ageing Res Rev 9, 107–116.
17.GR Gibson , KP Scott , RA Rastall , (2011) Dietary prebiotics: current status and new definition. Food Sci Tech Bull Funct Foods 7, 1–19.
19.W van Dokkum , B Wezendonk , TS Srikumar (1999) Effect of nondigestible oligosaccharides on large-bowel functions, blood lipid concentrations and glucose absorption in young healthy male subjects. Eur J Clin Nutr 53, 1–7.
21.D Watson , M O'Connell Motherway , MH Schoterman , (2013) Selective carbohydrate utilization by lactobacilli and bifidobacteria. J Appl Microbiol 114, 1132–1146.
22.DL Worthley , RK Le Leu , VL Whitehall , (2009) A human, double-blind, placebo-controlled, crossover trial of prebiotic, probiotic, and synbiotic supplementation: effects on luminal, inflammatory, epigenetic, and epithelial biomarkers of colorectal cancer. Am J Clin Nutr 90, 578–586.
23.S Fujimori , K Gudis , K Mitsui , (2009) A randomized controlled trial on the efficacy of synbiotic versus probiotic or prebiotic treatment to improve the quality of life in patients with ulcerative colitis. Nutrition 25, 520–525.
24.M Alander , J Mättö , W Kneifel , (2001) Effect of galacto-oligosaccharide supplementation on human faecal microflora and on survival and persistence of Bifidobacterium lactis Bb-12 in the gastrointestinal tract. Int Dairy J 11, 817–825.
31.W Manz , R Amann , W Ludwig , (1996) Application of a suite of 16S rRNA-specific oligonucleotide probes designed to investigate bacteria of the phylum Cytophaga–Flavobacter–Bacteroides in the natural environment. Microbiology 142, 1097–1106.
34.HJ Harmsen , AC Wildeboer-Veloo , J Grijpstra , (2000) Development of 16S rRNA-based probes for the Coriobacterium group and the Atopobium cluster and their application for enumeration of Coriobacteriaceae in human feces from volunteers of different age groups. Appl Environ Microbiol 66, 4523–4527.
35.A Sghir , G Gramet , A Suau , (2000) Quantification of bacterial groups within human fecal flora by oligonucleotide probe hybridization. Appl Environ Microbiol 66, 2263–2266.
36.A Suau , V Rochet , A Sghir , (2001) Fusobacterium prausnitzii and related species represent a dominant group within the human fecal flora. Syst Appl Microbiol 24, 139–145.
38.H Mäkelainen , S Forssten , M Saarinen , (2010) Xylo-oligosaccharides enhance the growth of bifidobacteria and Bifidobacterium lactis in a simulated colon model. Benef Microbes 1, 81–91.
39.M Ventura , R Reniero & R Zink (2001) Specific identification and targeted characterization of Bifidobacterium lactis from different environmental isolates by a combined multiplex–PCR approach. Appl Environ Microbiol 67, 2760–2765.
40.CN Larsen , S Nielsen , P Kaestel , (2006) Dose–response study of probiotic bacteria Bifidobacterium animalis subsp lactis BB-12 and Lactobacillus paracasei subsp paracasei CRL-341 in healthy young adults. Eur J Clin Nutr 60, 1284–1293.
41.LM Davis , I Martinez , J Walter , (2010) A dose dependent impact of prebiotic galactooligosaccharides on the intestinal microbiota of healthy adults. Int J Food Microbiol 144, 285–292.
42.LM Davis , I Martinez , J Walter , (2011) Barcoded pyrosequencing reveals that consumption of galactooligosaccharides results in a highly specific bifidogenic response in humans. PLoS ONE 6, e25200.
44.HS Gill , KJ Rutherfurd & ML Cross (2001) Dietary probiotic supplementation enhances natural killer cell activity in the elderly: an investigation of age-related immunological changes. J Clin Immunol 21, 264–271.
45.K Arunachalam , HS Gill & RK Chandra (2000) Enhancement of natural immune function by dietary consumption of Bifidobacterium lactis (HN019). Eur J Clin Nutr 54, 263–267.
46.EJ Schiffrin , F Rochat , H Link-Amster , (1995) Immunomodulation of human blood cells following the ingestion of lactic acid bacteria. J Dairy Sci 78, 491–497.
47.BL Chiang , YH Sheih , LH Wang , (2000) Enhancing immunity by dietary consumption of a probiotic lactic acid bacterium (Bifidobacterium lactis HN019): optimization and definition of cellular immune responses. Eur J Clin Nutr 54, 849–855.
48.B Foligne , S Nutten , C Grangette , (2007) Correlation between in vitro and in vivo immunomodulatory properties of lactic acid bacteria. World J Gastroenterol 13, 236–243.
49.C Franceschi , M Capri , D Monti , (2007) Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans. Mech Ageing Dev 128, 92–105.