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    Philibert, Robert Hollenbeck, Nancy Andersen, Eleanor McElroy, Shyheme Wilson, Scott Vercande, Kyra Beach, Steven R. H. Osborn, Terry Gerrard, Meg Gibbons, Frederick X. and Wang, Kai 2016. Reversion of AHRR Demethylation Is a Quantitative Biomarker of Smoking Cessation. Frontiers in Psychiatry, Vol. 7,


An Evaluation of a Novel Biomarker Feedback Intervention on Smoking Cessation: A Pilot Study

  • Jamie Hetherington (a1), Rosanne Coutts (a1) and Kade Davison (a1)
  • DOI:
  • Published online: 02 November 2012

Cessation is the single most important decision smokers can make to improve their health. The aim of this study was to investigate the effects of a novel biomarker feedback intervention on smoking cessation. Participants (n = 14) were block matched into two groups – biomarker feedback and standard care (control) – and encouraged to stop smoking without the support of any pharmacological aids. All participants received standard smoking cessation advice and also had physiological measures collected during both rest and sub-maximal exercise testing at baseline, week 6 and week 12. The standard care group only received the smoking cessation advice as their intervention, whereas the biomarker feedback group were also given individual feedback in relation to their physiological results. Cessation rates were not significantly different between groups (p = 0.56) at week 12 follow-up; however, a calculation of odds ratios (OR) suggests that the biomarker feedback group was more likely to be successful when compared to standard care (OR = 4.5). Results suggest that targeting health motivations may positively influence cessation rates. Future research is needed to verify this result with a larger group.

Corresponding author
Address for correspondence: Jamie Hetherington, School of Health and Human Sciences, Southern Cross University, PO Box 157, Lismore NSW 2480, Australia. E-mail:
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Journal of Smoking Cessation
  • ISSN: -
  • EISSN: 1834-2612
  • URL: /core/journals/journal-of-smoking-cessation
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