Szymkowicz, Sarah M. Dotson, Vonetta M. Jones, Jacob D. Okun, Michael S. and Bowers, Dawn 2017. Symptom Dimensions of Depression and Apathy and Their Relationship With Cognition in Parkinson’s Disease. Journal of the International Neuropsychological Society, p. 1.
Santangelo, Gabriella D’Iorio, Alfonsina Piscopo, Fausta Cuoco, Sofia Longo, Katia Amboni, Marianna Baiano, Chiara Tafuri, Domenico Pellecchia, Maria Teresa Barone, Paolo and Vitale, Carmine 2017. Assessment of apathy minimising the effect of motor dysfunctions in Parkinson’s disease: a validation study of the dimensional apathy scale. Quality of Life Research, Vol. 26, Issue. 9, p. 2533.
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Ang, Yuen-Siang Lockwood, Patricia Apps, Matthew A. J. Muhammed, Kinan Husain, Masud and Gulinello, Maria 2017. Distinct Subtypes of Apathy Revealed by the Apathy Motivation Index. PLOS ONE, Vol. 12, Issue. 1, p. e0169938.
Gerstenecker, Adam 2017. The Neuropsychology (Broadly Conceived) of Multiple System Atrophy, Progressive Supranuclear Palsy, and Corticobasal Degeneration. Archives of Clinical Neuropsychology, Vol. 32, Issue. 7, p. 861.
Groeneweg-Koolhoven, Isis Ploeg, Merel Comijs, Hannie C. WJH Penninx, Brenda van der Mast, Roos C. Schoevers, Robert A. Rhebergen, Didi and Exel, Eric van 2017. Apathy in early and late-life depression. Journal of Affective Disorders, Vol. 223, p. 76.
Camargo, Carlos Henrique Ferreria Serpa, Rafael Arthur Jobbins, Vinícius Aguiar Berbetz, Frederico Antonio and Sabatini, Jivago Szpoganicz 2017. Differentiating Between Apathy and Depression in Patients With Parkinson Disease Dementia. American Journal of Alzheimer's Disease & Other Dementiasr, p. 153331751772833.
Weintraut, Rita Karádi, Kázmér Lucza, Tivadar Kovács, Márton Makkos, Attila Janszky, József and Kovács, Norbert 2016. Lille Apathy Rating Scale and MDS-UPDRS for Screening Apathy in Parkinson’s Disease. Journal of Parkinson's Disease, Vol. 6, Issue. 1, p. 257.
Muhammed, Kinan Manohar, Sanjay Ben Yehuda, Michael Chong, Trevor T.-J. Tofaris, George Lennox, Graham Bogdanovic, Marko Hu, Michele and Husain, Masud 2016. Reward sensitivity deficits modulated by dopamine are associated with apathy in Parkinson’s disease. Brain, Vol. 139, Issue. 10, p. 2706.
Picillo, Marina Santangelo, Gabriella Moccia, Marcello Erro, Roberto Amboni, Marianna Prestipino, Elio Longo, Katia Vitale, Carmine Spina, Emanuele Orefice, Giuseppe Barone, Paolo and Pellecchia, Maria Teresa 2016. Serum uric acid is associated with apathy in early, drug-naïve Parkinson’s disease. Journal of Neural Transmission, Vol. 123, Issue. 4, p. 371.
Wee, Natalie Kandiah, Nagaendran Acharyya, Sanchalika Chander, Russell J. Ng, Aloysius Au, Wing Lok and Tan, Louis C.S. 2016. Baseline predictors of worsening apathy in Parkinson's disease: A prospective longitudinal study. Parkinsonism & Related Disorders, Vol. 23, p. 95.
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Camargo, Carlos Henrique Ferreira Serpa, Rafael Arthur Matnei, Thiago Sabatini, Jivago Szpoganicz and Teive, Hélio Afonso Ghizoni 2016. The perception of apathy by caregivers of patients with dementia in Parkinson's disease. Dementia & Neuropsychologia, Vol. 10, Issue. 4, p. 339.
The objective of this study was to test the hypothesis that apathy and depression are dissociable in Parkinson disease (PD) by conducting a confirmatory factor analysis (CFA) of items from two commonly used mood scales. A total of 161 non-demented PD patients (age = 64.1; ± 8.4 years) were administered the Apathy Scale and the Beck Depression Inventory-II. Items were hypothesized to load onto four factors: (1) an apathy factor representing loss of motivation, (2) dysphoric mood factor representing sadness and negativity, (3) loss of interest/pleasure factor representing the features common to both apathy and depression, and (4) a somatic factor representing bodily complaints. Results indicated a good fit for the overall CFA model, χ2 (128, N = 146) = 194.9; p<.01. RMSEA was .060 (p = .16). The four-factor model was significantly better than all alternative nested models at p < .001, including an overarching single factor model, representing “depression.” Results support the concept that apathy and depression are discrete constructs. We suggest a “factor based” scoring of the Apathy Scale and Beck Depression Inventory-II that disentangles symptoms related to apathy, depression, overlapping symptoms, and somatic complaints. Such scoring may be important in providing useful information regarding differential treatment options. (JINS, 2011, 17, 1058–1066)
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