Skip to main content
×
Home
    • Aa
    • Aa
  • Get access
    Check if you have access via personal or institutional login
  • Cited by 10
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Allali, Gilles Verghese, Joe and Mahoney, Jeannette R. 2014. Contributions of mild parkinsonian signs to gait performance in the elderly. AGE, Vol. 36, Issue. 4,


    Han, S. Duke Arfanakis, Konstantinos Fleischman, Debra A. Leurgans, Sue E. Tuminello, Elizabeth R. Edmonds, Emily C. and Bennett, David A. 2012. Functional Connectivity Variations in Mild Cognitive Impairment: Associations with Cognitive Function. Journal of the International Neuropsychological Society, Vol. 18, Issue. 01, p. 39.


    Fleischman, Debra A. Buchman, Aron S. Bienias, Julia L. and Bennett, David A. 2009. Visuoperceptual repetition priming and progression of parkinsonian signs in aging. Neurobiology of Aging, Vol. 30, Issue. 3, p. 441.


    Ciucci, Michelle R. Barkmeier-Kraemer, Julie M. and Sherman, Scott J. 2008. Subthalamic nucleus deep brain stimulation improves deglutition in Parkinson's disease. Movement Disorders, Vol. 23, Issue. 5, p. 676.


    Oertel, Wolfgang Poewe, Werner Wolters, Erik De Deyn, Peter Paul Emre, Murat Kirsch, Courtney Hsu, Chuanchieh Tekin, Sibel and Lane, Roger 2008. Effects of Rivastigmine on Tremor and Other Motor Symptoms in Patients with Parkinson’s Disease Dementia. Drug Safety, Vol. 31, Issue. 1, p. 79.


    Pell, Marc D. and Monetta, Laura 2008. How Parkinson's Disease Affects Non-verbal Communication and Language Processing. Language and Linguistics Compass, Vol. 2, Issue. 5, p. 739.


    Fleischman, Debra A. Wilson, Robert S. Schneider, Julie A. Bienias, Julia L. and Bennett, David A. 2007. Parkinsonian Signs and Functional Disability in Old Age. Experimental Aging Research, Vol. 33, Issue. 1, p. 59.


    Louis, Elan D. and Bennett, David A. 2007. Mild Parkinsonian signs: An overview of an emerging concept. Movement Disorders, Vol. 22, Issue. 12, p. 1681.


    Forjaz, Maria João and Martinez-Martin, Pablo 2006. Metric attributes of the unified Parkinson's disease rating scale 3.0 battery: Part II, construct and content validity. Movement Disorders, Vol. 21, Issue. 11, p. 1892.


    2006. Current awareness in geriatric psychiatry. International Journal of Geriatric Psychiatry, Vol. 21, Issue. 4, p. 401.


    ×
  • Journal of the International Neuropsychological Society, Volume 11, Issue 5
  • September 2005, pp. 591-597

Parkinsonian signs and cognitive function in old age

  • DEBRA A. FLEISCHMAN (a1) (a2) (a3), ROBERT S. WILSON (a1) (a2) (a3), JULIA L. BIENIAS (a1) (a4) and DAVID A. BENNETT (a1) (a2)
  • DOI: http://dx.doi.org/10.1017/S1355617705050708
  • Published online: 01 August 2005
Abstract

Studies have shown that parkinsonian signs are related to cognitive function in aging. What remains unclear is whether this association is stronger for some cognitive domains than it is for others, and precisely how much variability in global and specific cognitive functions is explained by the motor signs. We examined the associations between four parkinsonian signs (gait, rigidity, bradykinesia, tremor) and five cognitive domains (episodic memory, semantic memory, working memory, perceptual speed, visuospatial ability) in a large cohort of older persons who were free of Parkinson's disease and dementia and were participating in the Rush Memory and Aging Project. In a series of regression equations that controlled for age, sex, and education, higher levels of three signs (gait, rigidity, and bradykinesia) were related to lower levels of cognitive function, but they accounted for less than 5% of the variance in most measures. The results did not change when the presence of depressive symptoms, diabetes, and hypertension were added to the models. The cross-sectional association between parkinsonian signs and cognitive function did not vary substantially across specific cognitive domains or specific cognitive tests. The results suggest that parkinsonian signs have a modest, but statistically reliable, association with level of cognitive function in old age. (JINS, 2005, 11, 591–597.)

Copyright
Corresponding author
Address correspondence and reprint requests to: Debra A. Fleischman, Ph.D., Rush Alzheimer's Disease Center, Armour Academic Center Offices, 600 S. Paulina, Suite 1038, Chicago, IL. 60612. E-mail: Debra_Fleischman@rush.edu.
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Journal of the International Neuropsychological Society
  • ISSN: 1355-6177
  • EISSN: 1469-7661
  • URL: /core/journals/journal-of-the-international-neuropsychological-society
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords: