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Perceptual span deficits in adults with HIV

  • DAVID J. HARDY (a1), STEVEN A. CASTELLON (a1) (a2) and CHARLES H. HINKIN (a1) (a2)
Abstract

Studies have found that infection with the Human Immunodeficiency Virus (HIV) leads to cognitive dysfunction. In fact, attention problems have been reported to be the most frequent cognitive symptom in HIV-infected adults. One question is how early in the course of information processing can attention impairment be detected? To address this issue, performance on a perceptual span task was examined in 54 HIV-infected adults and 19 seronegative controls. In this task a target had to be identified in a briefly presented (50 ms) array of 1, 4, or 12 letter-characters. Response accuracy was differentially worse in the HIV+ group relative to seronegative controls in the most difficult condition, the 12-item array, but not in the easier conditions. There was no evidence of a group difference in response strategy due to disinhibition or in psychomotor speed. These data suggest that HIV infection leads to a reduction in early visual processing capacity (or span of apprehension). The present results illustrate a new type of attentional deficit in HIV and show the impact of HIV on cognition at an earlier point in information processing than has been previously reported. (JINS, 2004, 10, 135–140.)

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Reprint requests to: David J. Hardy, Ph.D., UCLA School of Medicine, 760 Westwood Plaza, Room C8-747, Los Angeles, CA 90024. E-mail: dhardy@ucla.edu
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Asarnow, R.F. & MacCrimmon, D.J. (1978). Residual performance deficit in clinically remitted schizophrenics: A marker for schizophrenia?Journal of Abnormal Psychology, 87, 597608.

Duncan, J. (1980). The demonstration of capacity limitation. Cognitive Psychology, 12, 7596.

Estes, W.K. & Taylor, H.A. (1964). A detection method and probabilistic models for assessing information processing from brief visual displays. Proceedings of the National Academy of Science, 52, 446454.

Estes, W.K. & Taylor, H.A. (1965). Visual detection in relation to display size and redundancy of critical elements. Perception and Psychophysics, 1, 915.

Grassi, B., Garghentini, G., Arturo, C., Grassi, E., Bertelli, S., Cinque, P., Epifani, M., Lazzarin, A., & Scarone, S. (1999). Spatial working memory in asymptomatic HIV-infected subjects. The Journal of Neuropsychiatry and Clinical Neurosciences, 11, 387391.

Hardy, D.J. & Hinkin, C.H. (2002). Reaction time performance in adults with HIV/AIDS. Journal of Clinical and Experimental Neuropsychology, 24, 912929.

Heaton, R.K., Grant, I., Butters, N., White, D.A., Kirson, D., Atkinson, J.H., McCutchan, J.A., Taylor, A., & the HNRC Group. (1995). The HNRC 500—Neuropsychology of HIV infection at different disease stages. Journal of the International Neuropsychological Society, 1, 231251.

Hinkin, C.H., Castellon, S.A., & Hardy, D.J. (2000). Dual task performance in HIV-1 infection. Journal of Clinical and Experimental Neuropsychology, 22, 1624.

Law, W.A., Mapou, R.L., Roller, T.L., Martin, A., Nannis, E.D., & Temoshok, L.R. (1995). Reaction time slowing in HIV-1-infected individuals: Role of the preparatory interval. Journal of Clinical and Experimental Neuropsychology, 17, 122133.

Martin, E.M., Pitrak, D.L., Pursell, K.J., Mullane, K.M., & Novak, R.M. (1995). Delayed recognition memory span in HIV-1 infection. Journal of the International Neuropsychological Society, 1, 575580.

Martin, E.M., Robertson, L.C., Edelstein, H.E., Jagust, W.J., Sorensen, D.J., Giovanni, D.S., & Chirurgi, V.A. (1992). Performance of patients with early HIV-1 infection on the Stroop task. Journal of Clinical and Experimental Neuropsychology, 14, 857868.

Miller, E.N., Satz, P., & Visscher, V. (1991). Computerized and conventional neuropsychological assessment of HIV-1-infected homosexual men. Neurology, 41, 16081616.

Neale, J.M., McIntyre, C.W., Fox, R., & Cromwell, R.L. (1969). Span of apprehension in acute schizophrenics. Journal of Abnormal Psychology, 74, 593596.

Sperling, G. (1960). The information available in brief visual presentations. Psychological Monographs, 74 (whole no. 498).

Tanner, W.P., Jr. (1961). Physiological implications of psychophysical data. Annals of the New York Academy of Science, 89, 752765.

van Gorp, W.G., Miller, E.N., Satz, P., & Visscher, B. (1989). Neuropsychological performance in HIV-1 immunocompromised patients: A preliminary report. Journal of Clinical and Experimental Neuropsychology, 11, 763773.

Wagener, D.K., Hogarty, G.E., Goldstein, M.J., Asarnow, R.F., & Browne, A. (1986). Information processing and communication deviance in schizophrenic patients and their mothers. Psychiatry Research, 18, 365377.

Worth, J.L., Savage, C.R., Baer, L., Esty, E.K., & Navia, B.A. (1993). Computer-based neuropsychological screening for AIDS dementia complex. AIDS, 7, 677681.

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Journal of the International Neuropsychological Society
  • ISSN: 1355-6177
  • EISSN: 1469-7661
  • URL: /core/journals/journal-of-the-international-neuropsychological-society
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