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High-Resolution Transmission Electron Microscopy Study of Nanostructured Hydroxyapatite

Published online by Cambridge University Press:  16 September 2008

Daniel Biggemann ,
Marcelo H. Prado da Silva ,
Alexandre M. Rossi  and
Antonio J. Ramirez
Daniel Biggemann
Affiliation:
Brazilian Synchrotron Light Laboratory, Caixa Postal 6192, Campinas-SP 13083-970, Brazil
Marcelo H. Prado da Silva
Affiliation:
Military Institute of Engineering, Pça. Gen. Tiburcio 80, Rio de Janeiro-RJ 22290-270, Brazil
Alexandre M. Rossi
Affiliation:
Brazilian Center for Physics Research, Rua Xavier Sigaud 150, Rio de Janeiro-RJ 22290-180, Brazil
Antonio J. Ramirez*
Affiliation:
Brazilian Synchrotron Light Laboratory, Caixa Postal 6192, Campinas-SP 13083-970, Brazil
*
Corresponding author. E-mail: ramirez@lnls.br
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Abstract

Crystalline properties of synthetic nanostructured hydroxyapatite (n-HA) were studied using high-resolution transmission electron microscopy. The focal-series-restoration technique, obtaining exit-plane wavefunction and spherical aberration-corrected images, was successfully applied for the first time in this electron-beam-susceptible material. Multislice simulations and energy dispersive X-ray spectroscopy were also employed to determine unequivocally that n-HA particles of different size preserve stoichiometric HA-like crystal structure. n-HA particles with sizes of twice the HA lattice parameter were found. These results can be used to optimize n-HA sinterization parameters to improve bioactivity.

Keywords

hydroxyapatiteHRTEMfocal seriesnanoparticles
Type
Materials Applications
Information
Microscopy and Microanalysis , Volume 14 , Issue 5 , October 2008 , pp. 433 - 438
Copyright
Copyright © Microscopy Society of America 2008

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References

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