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Ultrastructure of Lymphatic Stomata in the Tunica Vaginalis of Humans

Published online by Cambridge University Press:  09 August 2013

Jiaxiong Wang ,
Zepeng Ping ,
Tingting Jiang ,
Hongyuan Yu ,
Chong Wang ,
Zhongliang Chen ,
Xing Zhang ,
Dandan Xu ,
Li Wang  and
Zhongjie Li
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Jiaxiong Wang
Affiliation:
Institute of Cell Biology, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China
Zepeng Ping
Affiliation:
Institute of Cell Biology, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China
Tingting Jiang
Affiliation:
Institute of Cell Biology, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China
Hongyuan Yu
Affiliation:
Department of Urology, Taizhou Hospital of Zhejiang Province, 150 Ximen Street, Linhai 317000, China
Chong Wang
Affiliation:
Institute of Cell Biology, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China
Zhongliang Chen
Affiliation:
Institute of Cell Biology, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China
Xing Zhang
Affiliation:
Institute of Cell Biology, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China
Dandan Xu
Affiliation:
Institute of Cell Biology, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China
Li Wang
Affiliation:
Institute of Cell Biology, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China
Zhongjie Li
Affiliation:
Institute of Cell Biology, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China
Ji-Cheng Li*
Affiliation:
Institute of Cell Biology, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China
*
*Corresponding author. E-mail: lijichen@zju.edu.cn
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Abstract

Lymphatic stomata are small openings of lymphatic capillaries on the surface of the mesothelium that lines the serous cavity and have the function of active absorption. They play an important role in physiological and pathological conditions. The cavity of the tunica vaginalis is a typical serous cavity of the testis, but the lymphatic stomata of the tunica vaginalis of humans have never been reported. Here, we studied their ultrastructure by scanning and transmission electron microscopy. The submesothelial connective tissue with foramina was investigated after the mesothelial cells were digested using NaOH solution. We found the lymphatic stomata in cuboidal mesothelial cell regions of the parietal layer of the tunica vaginalis of humans with a diameter of about 1–2 μm. Sometimes, closed lymphatic stomata could be observed. Our study is the first to report the existence of lymphatic stomata of the tunica vaginalis of humans. We found that the tunica vaginalis cavity is connected with the lymphatic system through the stomata, which might provide a morphological basis for the drainage of hydrocele and tumor metastasis of the tunica vaginalis of humans.

Keywords

lymphatic stomatatunica vaginalisultrastructurehuman
Type
Biomedical and Biological Applications
Information
Microscopy and Microanalysis , Volume 19 , Issue 6 , December 2013 , pp. 1405 - 1409
Copyright
Copyright © Microscopy Society of America 2013 

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