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Self-assembled Carbon Nanotube-DNA Hybrids at the Nanoscale: Morphological and Conductive Properties Probed by Atomic Force Microscopy

Published online by Cambridge University Press:  09 June 2014

M. Gabriella Santonicola ,
Susanna Laurenzi  and
Peter M. Schön
M. Gabriella Santonicola*
Affiliation:
Department of Chemical Materials Environmental Engineering, Sapienza University of Rome, Via del Castro Laurenziano 7, 00161 Rome, Italy Materials Science and Technology of Polymers, MESA+ Institute for Nanotechnology, University of Twente, 7500 AE Enschede, The Netherlands
Susanna Laurenzi
Affiliation:
Department of Astronautic Electrical and Energy Engineering, Sapienza University of Rome, Via Salaria 851-881, 00138 Rome, Italy
Peter M. Schön
Affiliation:
Materials Science and Technology of Polymers, MESA+ Institute for Nanotechnology, University of Twente, 7500 AE Enschede, The Netherlands
*
*Corresponding author: mariagabriella.santonicola@uniroma1.it
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Abstract

Our research is focused on the engineering of novel, highly sensitive and miniaturized hybrid materials from carbon nanotubes (CNTs) and DNA molecules for applications in biosensors and medical devices. These hybrid sensors allow for a high degree of miniaturization, a key factor in the design of lightweight components while maintaining the advantages of in-situ and real-time analysis capabilities. In the first phase of the sensor design process, we investigated the structural and electrical properties of the supramolecular complexes made of amide-functionalized CNTs and double-stranded DNA. The solubilization properties of the hybrid nanotubes in aqueous solutions with different concentrations of DNA were studied, and an optimal ratio of nanotubes and biomolecules to achieve a good level of dispersion was found. Complexes formed in aqueous solution from CNTs and DNA are highly stable and maintain their properties up to one month from preparation. The morphology of the CNT-DNA composites was investigated at the nanoscale level using atomic force microscopy (AFM) and electron microscopy (SEM). Results from these experiments show the strong affinity between the surface of the amide-functionalized CNTs and the DNA strands. Further, the CNT-DNA films were investigated by atomic force microscopy in the PeakForce TUNA mode to assess the suitability of this technique in determining the local conductive properties of the hybrid films.

Keywords

nanoscalescanning probe microscopy (SPM)self-assembly
Type
Articles
Information
MRS Online Proceedings Library (OPL) , Volume 1700: Symposium MM – Nanotubes and Related Nanostructures--2014 , 2014 , pp. 47 - 52
Copyright
Copyright © Materials Research Society 2014 

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References

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