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Domestic dogs and cats as sources of Trypanosoma cruzi infection in rural northwestern Argentina

  • R. E. GÜRTLER (a1), M. C. CECERE (a1), M. A. LAURICELLA (a2), M. V. CARDINAL (a1), U. KITRON (a3) and J. E. COHEN (a4)...
Abstract

The reservoir capacity of domestic cats and dogs for Trypanosoma cruzi infection and the host-feeding patterns of domestic Triatoma infestans were assessed longitudinally in 2 infested rural villages in north-western Argentina. A total of 86 dogs and 38 cats was repeatedly examined for T. cruzi infection by serology and/or xenodiagnosis. The composite prevalence of infection in dogs (60%), but not in cats, increased significantly with age and with the domiciliary density of infected T. infestans. Dogs and cats had similarly high forces of infection, prevalence of infectious hosts (41–42%), and infectiousness to bugs at a wide range of infected bug densities. The infectiousness to bugs of seropositive dogs declined significantly with increasing dog age and was highly aggregated. Individual dog infectiousness to bugs was significantly autocorrelated over time. Domestic T. infestans fed on dogs showed higher infection prevalence (49%) than those fed on cats (39%), humans (38%) or chickens (29%) among 1085 bugs examined. The basic reproduction number of T. cruzi in dogs was at least 8·2. Both cats and dogs are epidemiologically important sources of infection for bugs and householders, dogs nearly 3 times more than cats.

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Corresponding author
Departamento de Ecología, Genética y Evolución, FCEN-UBA, Ciudad Universitaria, 1428 Buenos Aires, Argentina. Tel: +54 11 4576 3318. Fax: +54 11 4576 3384. E-mail: gurtler@ege.fcen.uba.ar
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Araújo, F. M. G., Bahia, M. T., Magalhães, N. M., Martins-Filho, O. A., Veloso, V. M., Carneiro, C. M., Tafuri, W. L. and Lana, M. ( 2002). Follow-up of experimental chronic Chagas' disease in dogs: use of polymerase chain reaction (PCR) compared with parasitological and serological methods. Acta Tropica81, 2131.

Beard, C. B., Pye, G., Steurer, F. J., Rodriguez, R., Campman, R., Peterson, A. T., Ramsey, J., Wirtz, R. A. and Robinson, L. E. ( 2003). Chagas disease in a domestic transmission cycle, southern Texas, USA. Emerging Infectious Diseases9, 103105.

Castañera, M. B., Lauricella, M. A., Chuit, R. and Gürtler, R. E. ( 1998). Evaluation of dogs as sentinels of the transmission of Trypanosoma cruzi in a rural area of north-west Argentina. Annals of Tropical Medicine and Parasitology92, 671683.

Catalá, S. S., Crocco, L. B., Muñoz, A., Morales, G., Paulone, I., Giraldez, E., Candioti, C. and Ripol, C. ( 2004). Entomological aspects of Chagas' disease transmission in the domestic habitat, Argentina. Revista Saúde Pública38, 216222.

Cleaveland, S. and Dye, C. ( 1995). Maintenance of a microparasite infecting several host species: rabies in the Serengeti. Parasitology111, S33S47.

Courtenay, O., Quinnell, R. J., Garcez, L. M., Shaw, J. J. and Dye, C. ( 2002). Infectiousness in a cohort of brazilian dogs: why culling fails to control visceral leishmaniasis in areas of high transmission. Journal of Infectious Diseases186, 13141320.

Dias, J. C. P., Silveira, A. C. and Schofield, C. J. ( 2002). The impact of Chagas disease control in Latin America – A review. Memorias do Instituto Oswaldo Cruz97, 603612.

Gürtler, R. E., Kravetz, F. O., Petersen, R. M., Lauricella, M. A. and Wisnivesky-Colli, C. ( 1990). The prevalence of Trypanosoma cruzi and the demography of dog populations after insecticidal spraying of houses: a predictive model. Annals of Tropical Medicine and Parasitology84, 313323.

Gürtler, R. E., Petersen, R. M., Lauricella, M. A. and Wisnivesky-Colli, C. ( 1992a). Infectivity to the vector Triatoma infestans of dogs infected with Trypanosoma cruzi in north-west Argentina. Annals of Tropical Medicine and Parasitology86, 111119.

Gürtler, R. E., Cecere, M. C., Rubel, D. N. and Schweigmann, N. J. ( 1992b). Determinants of the domiciliary density of Triatoma infestans, vector of Chagas disease. Medical and Veterinary Entomology6, 7583.

Gürtler, R. E., Cécere, M. C., Petersen, R. M., Rubel, D. N. and Schweigmann, N. J. ( 1993). Chagas disease in north-west Argentina: association between Trypanosoma cruzi parasitaemia in dogs and cats and infection rates in domestic Triatoma infestans. Transactions of the Royal Society of Tropical Medicine and Hygiene87, 1215.

Gürtler, R. E., Cohen, J. E., Cecere, M. C. and Chuit, R. ( 1997). Shifting host choices of the vector of Chagas disease Triatoma infestans in relation to the availability of hosts in houses in north-west Argentina. Journal of Applied Ecology34, 699715.

Kilpatrick, A. M., Kramer, L. D., Campbell, S. R., Alleyne, E. O., Dobson, A. P. and Daszak, P. ( 2005). West Nile virus risk assessment and the bridge vector paradigm. Emerging Infectious Diseases11, 425429.

Kirk, M. L. and Schofield, C. J. ( 1987). Density-dependent timing of defaecation by Rhodnius prolixus, and its implications for the transmission of Trypanosoma cruzi. Transactions of the Royal Society of Tropical Medicine and Hygiene81, 348349.

Lauricella, M. A., Sinagra, A. J., Paulone, I., Riarte, A. R. and Segura, E. L. ( 1989). Natural Trypanosoma cruzi infection in dogs of endemic areas of the Argentine Republic. Revista do Instituto de Medicina Tropical de São Paulo31, 6370.

Lauricella, M. A., Castañera, M. B., Gürtler, R. E. and Segura, E. L. ( 1998). Immunodiagnosis of Trypanosoma cruzi (Chagas' Disease) infection in naturally infected dogs. Memorias do Instituto Oswaldo Cruz93, 501507.

Lloyd-Smith, J. O., Schreiber, S. J., Kopp, P. E. and Getz, W. M. ( 2005). Superspreading and the effect of individual variation on disease emergence. Nature, London438, 355359.

Muench, H. ( 1959). Catalytic Models in Epidemiology. Harvard University Press, Cambridge, MA, USA.

Petersen, R. M., Gürtler, R. E., Cecere, M. C., Rubel, D. N., Hansen, D., Lauricella, M. A. and Carlomagno, M. ( 2001). Association between nutritional indicators of dogs seroreactive for Trypanosoma cruzi in a rural area of northwestern Argentina. Parasitology Research87, 208214.

Quinnell, R. J., Courtenay, O., Garcez, L. and Dye, C. ( 1997). The epidemiology of canine leishmaniasis: transmission rates estimated from a cohort study in Amazonian Brazil. Parasitology115, 143156.

Rabinovich, J. E. and Himschoot, P. ( 1990). A population-dynamics simulation model of the main vectors of Chagas' disease transmission, Rhodnius prolixus and Triatoma infestans. Ecological Modelling52, 249266.

Reithinger, R., Ceballos, L. A., Stariolo, R., Davies, C. R. and Gürtler, R. E. ( 2005). Chagas disease control: deltamethrin-treated collars reduce Triatoma infestans feeding success on dogs. Transactions of the Royal Society of Tropical Medicine and Hygiene99, 502508.

Riarte, A., Sinagra, A., Lauricella, M., Bolomo, N., Moreno, M., Cossio, P., Arana, R. and Segura, E. L. ( 1995). Chronic experimental infection by Trypanosoma cruzi in Cebus apella monkeys. Memorias do Instituto Oswaldo Cruz90, 733740.

Wisnivesky-Colli, C., Gürtler, R. E., Solarz, N. D., Salomón, D. O. and Ruiz, A. M. ( 1982). Feeding patterns of Triatoma infestans (Hemiptera, Reduviidae) in relation to transmission of American Trypanosomiasis in Argentina. Journal of Medical Entomology19, 645654.

Wisnivesky-Colli, C., Gürtler, R. E., Solarz, N. D., Lauricella, M. A. and Segura, E. L. ( 1985). Epidemiological role of humans, dogs and cats in the transmission of Trypanosoma cruzi in a central area of Argentina. Revista do Instituto de Medicina Tropical de São Paulo27, 346352.

Woolhouse, M. E. J., Dye, C., Etard, J. F., Smith, T., Charlewood, J. D., Garnett, G. P., Hagan, P., Hii, J. L. K., Ndhlovu, P. D., Quinnell, R. J., Watts, C. H., Chandiwana, S. K. and Anderson, R. M. ( 1997). Heterogeneities in the transmission of infectious agents: implications for the design of control programs. Proceedings of the National Academy of Sciences, USA94, 338342.

Zárate, L. G., Zárate, R. J., Tempelis, C. H. and Goldsmith, R. S. ( 1980). The biology and behavior of Triatoma barberi (Hemiptera: Reduviidae) in Mexico. I. Blood meal sources and infection with Trypanosoma cruzi. Journal of Medical Entomology17, 103116.

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Parasitology
  • ISSN: 0031-1820
  • EISSN: 1469-8161
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