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Efficacy of the EG95 hydatid vaccine in a macropodid host, the tammar wallaby

  • T. S. BARNES (a1), L. A. HINDS (a2), D. J. JENKINS (a3) (a4), G. T. COLEMAN (a1), A. L. COLEBROOK (a5), C. T. KYNGDON (a5), C. G. GAUCI (a5) and M. W. LIGHTOWLERS (a5)...


In Australia, macropodids are common intermediate hosts for the cestode Echinococcus granulosus, and sylvatic transmission is maintained via wild dogs. The parasite causes mortality in a number of macropodid species and the sylvatic cycle provides a source of infection to domestic livestock and humans. We determined the efficacy of the hydatid vaccine, EG95 in the tammar wallaby, Macropus eugenii, challenging either 1 or 9 months post-vaccination. EG95 provides similar protection to that seen in sheep (96–100%). Control tammars were significantly more likely to become infected (odds ratio 29·44; CI 4·13, 209·97; P=0·001) and to develop more cysts (count ratio 26·69; CI 5·83, 122·19; P<0·001). The vaccination may be beneficial if administered pre-release in captive breeding programmes for endangered macropodids. Further work to develop oral delivery methods may enable vaccine administration of wild animals and thereby a reduction in sylvatic transmission.


Corresponding author

*Corresponding author: The University of Queensland, School of Veterinary Science, Queensland, 4072, Australia. Tel: +61 7 3365 3023. Fax: +61 7 3365 1255. E-mail:


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Efficacy of the EG95 hydatid vaccine in a macropodid host, the tammar wallaby

  • T. S. BARNES (a1), L. A. HINDS (a2), D. J. JENKINS (a3) (a4), G. T. COLEMAN (a1), A. L. COLEBROOK (a5), C. T. KYNGDON (a5), C. G. GAUCI (a5) and M. W. LIGHTOWLERS (a5)...


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