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Geographical distribution and epidemiological features of Old World Leishmania infantum and Leishmania donovani foci, based on the isoenzyme analysis of 2277 strains

  • FRANCINE PRATLONG (a1), PATRICK LAMI (a1), CHRISTOPHE RAVEL (a1), YVES BALARD (a1), JACQUES DEREURE (a1), GHISLAINE SERRES (a1), FOUAD EL BAIDOURI (a1) and JEAN-PIERRE DEDET (a1)...

Summary

A series of 2277 Leishmania strains from Old World visceral leishmaniasis foci, isolated between 1973 and 2008, were studied by isoenzyme analysis. The strains were obtained from humans, domestic and wild carnivores, rodents and phlebotomine sandflies, and came from 36 countries. In all, 60 different zymodemes were identified and clustered by a phenetic analysis into 3 different groups corresponding to the typically visceralizing species L. donovani (20 zymodemes, 169 strains), L. archibaldi (3 zymodemes, 46 strains) and L. infantum (37 zymodemes, 2,062 strains). The taxonomic position of these isoenzymatic groups is discussed in view of contradictory results obtained from recent molecular studies.

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*Corresponding author: Département de Parasitologie-Mycologie, 39 avenue Charles Flahault, 34295 Montpellier Cedex 5, France. Tel: 334 67 33 23 50. Fax: 334 67 33 23 58. E-mail: parasito@univ-montp1.fr

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Geographical distribution and epidemiological features of Old World Leishmania infantum and Leishmania donovani foci, based on the isoenzyme analysis of 2277 strains

  • FRANCINE PRATLONG (a1), PATRICK LAMI (a1), CHRISTOPHE RAVEL (a1), YVES BALARD (a1), JACQUES DEREURE (a1), GHISLAINE SERRES (a1), FOUAD EL BAIDOURI (a1) and JEAN-PIERRE DEDET (a1)...

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