Hostname: page-component-76fb5796d-vvkck Total loading time: 0 Render date: 2024-04-25T17:56:13.437Z Has data issue: false hasContentIssue false

The Use of Race in Medicine as a Proxy for Genetic Differences

Published online by Cambridge University Press:  01 January 2022

Abstract

Race is a prominent category in medicine. Epidemiologists describe how rates of morbidity and mortality vary with race, and doctors consider the race of their patients when deciding whether to test them for sickle-cell anemia or what drug to use to treat their hypertension. At the same time, critics of racial classification say that race is not real but only an illusion or that race is scientifically meaningless. In this paper, I explain how race is used in medicine as a proxy for genes that encode drug metabolizing enzymes and how a proper understanding of race calls into doubt the practice of treating race as a marker of any medically relevant genetic trait.

Type
Science and Social Context
Copyright
Copyright © The Philosophy of Science Association

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

American Heart Association (2001), 2001 Heart and Stroke Statistical Update. Dallas, TX: American Heart Association.Google Scholar
Cavalli-Sforza, L., Meonozzi, Paoli, and Piazza, Alberto (1994), The History and Geography of Human Genes, Princeton: Princeton University Press, 7980.Google Scholar
Cooper, Richard (1993), “Health and the Social Status of Blacks in the United States”, Health and the Social Status of Blacks in the United States 3:137144.Google ScholarPubMed
Cooper, R. S. and Cooper, David R. (1986), “The Biological Concept of Race and Its Application to Public Health and Epidemiology”, The Biological Concept of Race and Its Application to Public Health and Epidemiology 11:97116.Google ScholarPubMed
Exner, Derek V., Dries, Daniel L., Domanski, Michael J., and Cohn, Jay N. (2001), “Lesser Response to Angiotensin-Converting-Enzyme Inhibitor Therapy in Black as Compared with White Patients with Left Ventricular Dysfunction”, Lesser Response to Angiotensin-Converting-Enzyme Inhibitor Therapy in Black as Compared with White Patients with Left Ventricular Dysfunction 344:13511357.Google Scholar
Fein, Oliver (1995), “The Influence of Social Class on Health Status: American and British Research on Health Inequalities”, The Influence of Social Class on Health Status: American and British Research on Health Inequalities 10:577586.Google ScholarPubMed
Harris, David R. (2000), “Demography's Race Problem”, paper presented at the 2000 Meeting of the Population Association of America (available at the National Institute of Health website, http://www.nichd.nih.gov/cpr/dbs/sp/harris.htm).Google Scholar
Hempel, Carl G. (1965), Aspects of Scientific Explanation. New York: The Free Press, 6566.Google Scholar
Jones, C. P., La Veist, T. A., and Little-Blanton, M. (1991), “‘Race’ in the Epidemiologic Literature: An Examination of the American Journal of Epidemiology, 1921–1990”, ‘Race’ in the Epidemiologic Literature: An Examination of the American Journal of Epidemiology, 1921–1990 134:10791084.Google ScholarPubMed
Jones, J. S. (1981), “How Different are Human Races”, How Different are Human Races 293:188190.Google ScholarPubMed
Tapper, Melbourne (1999), In The Blood: Sickle-cell Anemia and the Politics of Race. Philadelphia: University of Pennsylvania Press.Google Scholar