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Comparison of Fluosol DA with Dextran 70 for Treatment of Acute Massive Hemorrhage

  • Takayuki Sakai (a1) and Masuhiko Takaori (a1)
Extract

Clinical experiences on perfluorochemical emulsion as an artificial blood has confirmed that perfluorochemical could transport oxygen indefinitely in circulating blood. We felt that an adequate cardiac output could be maintained no longer due to concomitant hypovolemia after the replacement with perfluorochemical emulsion for massive hemorrhage. Few studies have been reported on changes in the blood volume after replacement of circulating blood volume with fluorochemical.

Copyright
COPYRIGHT: © World Association for Disaster and Emergency Medicine 1985
References
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1. Fowler, NO, Franch, RH, Bloom, WL. Hemodynamic effects of anemia with and without plasma volume expansion. Circ Res 1956;4:319.
2. Fowler, NO, Holmes, JC. Blood viscosity and cardiac output in acute experimental anemia. J Appl Physiol 1975;39:453.
3. Oda, T, Takaori, M. Acute anemia and cardiac output. Respir Circ (Tokyo) 1971;19:947.
4. Takori, M, Safar, P. Acute, severe hemodilution with lactated Ringer's solution. Arch Surg 1967;94:67.
5Takaori, M, Safar, P, Galla, SJ. Changes in body fluid compartments during hemodilution with HES and dextran 40. Arch Surg 1970;100:263.
6. Takaori, M, Nakajo, N, Oosumi, A. Distribution of perfluorochemical particles in vessels of organs. Proc IV Intern Symp Perfluoroc hem Blood Subst (Kyoto) Excerpta Medica Amsterdam 1978:409.
7. Geyer, RP. Review of perftuorochemical-type blood substitute. Proc X Intern Congr Nutr Sympon PFC Artif Blood (Kyoto) Igakushoin, Tokyo 1975:3.
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Prehospital and Disaster Medicine
  • ISSN: 1049-023X
  • EISSN: 1945-1938
  • URL: /core/journals/prehospital-and-disaster-medicine
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