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Modern fat technology: what is the potential for heart health?

  • J. E. Upritchard (a1), M. J. Zeelenberg (a1), H. Huizinga (a1), P. M. Verschuren (a1) and E. A. Trautwein (a1)...
Abstract

Saturated and trans-fatty acids raise total cholesterol and LDL-cholesterol and are known to increase the risk of CHD, while dietary unsaturated fatty acids play important roles in maintaining cardiovascular health. Replacing saturated fats with unsaturated fats in the diet often involves many complex dietary changes. Modifying the composition of foods high in saturated fat, particularly those foods that are consumed daily, can help individuals to meet the nutritional targets for reducing the risk of CHD. In the 1960s the Dutch medical community approached Unilever about the technical feasibility of producing margarine with a high-PUFA and low-saturated fatty acid composition. Margarine is an emulsion of water in liquid oil that is stabilised by a network of fat crystals. In-depth expertise of fat crystallisation processes allowed Unilever scientists to use a minimum of solid fat (saturated fatty acids) to structure a maximum level of PUFA-rich liquid oil, thus developing the first blood-cholesterol-lowering product, Becel. Over the years the composition of this spread has been modified to reflect new scientific findings and recommendations. The present paper will briefly review the developments in fat technology that have made these improvements possible. Unilever produces spreads that are low in total fat and saturated fat, virtually free of trans-fatty acids and with levels of n-3 and n-6 PUFA that are in line with the latest dietary recommendations for the prevention of CHD. Individuals with the metabolic syndrome have a 2–4-fold increased risk of developing CHD; therefore, these spreads could make a contribution to CHD prevention in this group. In addition, for individuals with the metabolic syndrome the spreads could be further modified to address their unique dyslipidaemia, i.e. elevated blood triacylglycerols and low HDL-cholesterol. Research conducted in the LIPGENE study and other dietary intervention studies will deliver the scientific evidence to justify further modifications in the composition of spreads that are healthy for the heart disease risk factors associated with the metabolic syndrome.

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Corresponding author
* Corresponding author: Dr Jane Upritchard, fax + 31 104 605 993, Jane.Upritchard@Unilever.com
References
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AscherioA, RimmEB, GiovannucciEL, SpiegelmanD, StampferM, WillettWC (1996) Dietary fat and risk of coronary heart disease in men: cohort follow up study in the United States. British Medical Journal 313, 8490
AssmannG, SchulteH, von EckardsteinA, HuangY (1996) High-density lipoprotein cholesterol as a predictor of coronary heart disease risk. The PROCAM experience and pathophysiological implications for reverse cholesterol transport. Atherosclerosis 124, S11S20 Suppl.
AustinMA, HokansonJE, EdwardsKL (1998) Hypertriglyceridemia as a cardiovascular risk factor. American Journal of Cardiology 81, 7B12B
British Heart, Foundation Statistics (2004) CHD 2004: Mortality chapter http://www.heartstats.org/temp/Mortalityspchapter.pdf
BucherHC, HengstlerP, SchindlerC, MeierG (2002) N-3 polyunsaturated fatty acids in coronary heart disease: a meta-analysis of randomized controlled trials. American Journal of Medicine 112, 298304
BurrML, FehilyAM, GilbertJF, RogersS, HollidayRM, SweetnamPM, ElwoodPC, DeadmanNM (1989) Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: diet and reinfarction trial (DART). Lancet ii, 757761
ClarkeR, FrostC, CollinsR, ApplebyP, PetoR (1997) Dietary lipids and blood cholesterol: quantitative meta-analysis of metabolic ward studies. British Medical Journal 314, 112117
DaytonS, PearceML (1969) Prevention of coronary heart disease and other complications of arteriosclerosis by modified diet. American Journal of Medicine 46, 751762
DaytonS, PearceM, HashimotoS (1969) A controlled clinical trial of a diet high in unsaturated fat in preventing complications of atherosclerosis. Circulation 40, S11S63
De LorgerilM, SalenP, MartinJL, MonjaudI, DelayeJ, MamelleN (1999) Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report of the Lyon Diet Heart Study. Circulation 99, 779785
Department of HealthDepartment of Health (2005) Dietary guidelines for Americans. http://www.healthierus.gov/dietaryguidelines/ (accessed February 2005).
DjousseL, FolsomAR, ProvinceMA, HuntSC, EllisonRC (2003) Dietary linolenic acid and carotid atherosclerosis: the National Heart, Lung, and Blood Institute Family Heart Study. American Journal of Clinical Nutrition 77, 819825
DolecekTA (1992) Epidemiological evidence of relationships between dietary polyunsaturated fatty acids and mortality in the multiple risk factor intervention trial. Proceedings of the Society for Experimental Biology and Medicine 200, 177182
Eurodiet (2001) Eurodiet core report. Nutrition and diet for healthy lifestyles in Europe: science and policy implications. Public Health Nutrition 4, 265273
Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (2001) Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Journal of the American Medical Association 285, 24862497
FinneganYE, HowarthD, MinihaneAM, KewS, MillerGJ, CalderPC, WilliamsCM (2003) Plant and marine derived (n-3) polyunsaturated fatty acids do not affect blood coagulation and fibrinolytic factors in moderately hyperlipidemic humans. Journal of Nutrition 133, 22102213
Food Standards AgencyFood Standards Agency (2004) European Food Standards Agency Opinion. EFSA-Q-2003–022 – London FSA.
FrankelE (1998) Lipid Oxidation Bridgewater, Somerset PJ Barnes & Associates
FrantzID, JrDawson, EAAshman, PLGatewood, LCBartsch, GEKuba, K BrewerER (1989) Test of effect of lipid lowering by diet on cardiovascular risk. The Minnesota Coronary Survey. Arteriosclerosis 9, 129135
German Nutrition Society (2000) Referenzwertefür die Nährstoffzuhr (Reference Values for Nutrient Intake Bonn, Germany: DGE-Medien Service
GoyensPL, SpilkerME, ZockPL, KatanMB, MensinkRP (2005) Development of a compartmental model to quantify alpha-linolenic acid conversion after longer-term intake of multiple tracer boluses Journal of Lipid Research
HegstedDM, AusmanLM, JohnsonJA, DallalGE (1993) Dietary fat and serum lipids: an evaluation of the experimental data. American Journal of Clinical Nutrition 57, 875883
HjermannI, VelveBK, HolmeI, LerenP (1981) Effect of diet and smoking intervention on the incidence of coronary heart disease. Report from the Oslo Study Group of a randomised trial in healthy men. Lancet ii, 13031310
HooperL, ThompsonRL, HarrisonRA, SummerbellCD, MooreH, WorthingtonHV et al. (2004) Omega 3 fatty acids for prevention and treatment of cardiovascular disease. The Cochrane Database of Systematic Reviews 2004 4 http://www.mrw.interscience.wiley.com/cochrane/clsysrev/articles/CD003177/frame.html
HowellWH, McNamaraDJ, ToscaMA, SmithBT, GainesJA (1997) Plasma lipid and lipoprotein responses to dietary fat and cholesterol: a meta-analysis. American Journal of Clinical Nutrition 65, 17471764
HuFB, StampferMJ, MansonJE, RimmE, ColditzGA, RosnerBA, HennekensCH, WillettWC (1997) Dietary fat intake and the risk of coronary heart disease in women. New England Journal of Medicine 337, 14911499
HulshofKFAM, van Erp-BaartMA, AnttolainenM, BeckerW, ChurchSM, CouetC et al. . (1999) Intake of fatty acids in Western Europe with emphasis on trans fatty acids: The TRANSFAIR study. European Journal of Clinical Nutrition 53, 143157
Institute of, Nutritional Sciences (2003) Austrian Nutrition Report. Vienna, Austria: Federal Ministry of Health and Women.
JousilahtiP, VartiainenE, PekkanenJ, TuomilehtoJ, SundvallJ, PuskaP (1998) Serum cholesterol distribution and coronary heart disease risk: observations and predictions among middle-aged population in eastern Finland. Circulation 97, 10871094
KannelWB, CastelliWP, GordonT (1979) Cholesterol in the prediction of atherosclerotic disease. New perspectives based on the Framingham study. Annals of Internal Medicine 90, 8591
KeysA (1965) Effects of different dietary fats on plasma lipid levels. Lancet i, 318319
Kris-EthertonPM, HarrisWS, AppelLJ (2003) Omega-3 fatty acids and cardiovascular disease: new recommendations from the American Heart Association. Arteriosclerosis, Thrombosis, and Vascular Biology 23, 151152
LawMR, WaldNJ, ThompsonSG (1994) By how much and how quickly does reduction in serum cholesterol concentration lower risk of ischaemic heart disease. British Medical Journal 308, 367373
LerenP (1970) The Oslo diet-heart study. Eleven-year report. Circulation 42, 935942
MarchioliR, BarziF, BombaE, ChieffoC, DiGregorio, DDi, MascioR et al. . (2002) Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: time-course analysis of the results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI)-Prevenzione. Circulation 105, 18971903
MartinMJ, HulleySB, BrownerWS, KullerLH, WentworthD (1986) Serum cholesterol, blood pressure, and mortality: implications from a cohort of 361, 662 men. Lancet ii, 933936
MensinkRP, ZockPL, KesterAD, KatanMB (2003) Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials. American Journal of Clinical Nutrition 77, 11461155
MiettinenM, TurpeinenO, KarvonenMJ, PekkarinenM, PaavilainenE, ElosuoR (1983) Dietary prevention of coronary heart disease in women: the Finnish mental hospital study. International Journal of Epidemiology 12, 1725
NationalCouncil, onNutrition (1997) Voedingesaanbe Verlingen voor België (Dietary Recommendation for Belgium). Ministry of Social Affairs, Public Health and Environment Publication no. D/1996/7795/12 Brussels, Belgium Ministry of Social Affairs, Public Health and Environment
National Health and, Medical Research Council (2003) Dietary Guidelines for Australian Adults Canberra, ACT National Health and Medical Research Council
National Institutes, of Health (1998) Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults Bethesda, MA NIH, National Heart, Lung and Blood Institute
National Nutrition Council (1999) Finnish Nutritional Recommendations Helsinki, Finland Ministry of Agriculture and Forestry
NishidaC, UauyR, KumanyikaS, ShettyP (2004) The Joint WHO/FAO Expert Consultation on diet, nutrition and the prevention of chronic diseases: process, product and policy implications. Public Health Nutrition 7, 245250
PedersenTR, OlssonAG, FaergemanO, KjekshusJ, WedelH, BergK et al. . (1998) Lipoprotein changes and reduction in the incidence of major coronary heart disease events in the Scandinavian Simvastatin Survival Study (4S). Circulation 97, 14531460
PietinenP, AscherioA, KorhonenP, HartmanAM, WillettWC, AlbanesD, VirtamoJ (1997) Intake of fatty acids and risk of coronary heart disease in a cohort of Finnish men. The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study. American Journal of Epidemiology 145, 876887
SandströmB, LyhneN, PetersenJI, AroA, ThorsdóttirI, BeckerW (1996) Nordic nutrition recommendations. Scandinavian Journal of Nutrition 40, 161165
SinghRB, NiazMA, SharmaJP, KumarR, RastogiV, MoshiriM (1997) Randomized, double-blind, placebo-controlled trial of fish oil and mustard oil in patients with suspected acute myocardial infarction: the Indian experiment of infarct survival-4. Cardiovascular Drugs and Therapy 11, 485491
TurpeinenO (1979) Effect of cholesterol-lowering diet on mortality from coronary heart disease and other causes. Circulation 59, 17
TurpeinenO, KarvonenMJ, PekkarinenM, MiettinenM, ElosuoR, PaavilainenE (1979) Dietary prevention of coronary heart disease: the Finnish Mental Hospital Study. International Journal of Epidemiology 8, 99118
US Department of AgricultureUS Department of Agriculture (2002) USDA National Nutrient Database for Standard Reference, release 15. http://www.nal.usda.gov/fnic/foodcomp (accessed January 2005).
WillettWC, StampferMJ, MansonJE, ColditzGA, SpeizerFE, RosnerBA, SampsonLA, HennekensCH (1993) Intakes of trans fatty acids and risk of coronary heart disease among women. Lancet 341, 581585
World Health OrganizationWorld Health Organization (2003) Diet, Nutrition and the Prevention of Chronic Diseases. Joint WHO/FAO Expert Consultation. WHO Technical Report Series no. 916. Geneva: WHO.
Yu-PothS, ZhaoG, EthertonT, NaglakM, JonnalagaddaS, Kris-EthertonPM (1999) Effects of the National Cholesterol Education Program's Step I and Step II dietary intervention programs on cardiovascular disease risk factors: a meta-analysis. American Journal of Clinical Nutrition 69, 632646
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