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Co-occurrence of Gilbert's syndrome and psychosis

  • A. S. Mahdi and M. S. Elameer (a1)
Abstract

Idiopathic unconjugated hyperbilirubinaemia (Gilbert's syndrome) is a common benign disorder that, when seen in association with psychiatric illnesses, often leads to the inappropriate withholding of psychotropic medication. We describe three cases with Gilbert's syndrome and psychosis in which diagnosis of Gilbert's syndrome was delayed. This led to unnecessary investigations, further relapses and increased admissions to hospital. We emphasise the need for psychiatrists to be more aware of this benign condition.

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Copyright
This is an Open Access article, distributed under the terms of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
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References
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Davidson, A. R., Rojas-Beuno, A., Thompson, R. P. H., et al (1975) Reduced caloric intake of nicotinic acid provocation tests in the diagnosis of Gilbert's syndrome. British Medical Journal, ii, 480.
Blanckaert, N. & Fevery, J. (1990) Physiology and pathophysiology of bilirubin metabolism. In Hepatology: A Textbook of Liver Disease (eds Zakim, T. & Boyer, T. D.). pp. 254285. Philadelphia, PA: W. B. Saunders.
Cohen, L. S. & Cohen, D. E. (1992) Lithium induced hyperbilirubinaemia in an adolescent. Journal of Clinical Psychopharmacology, 11, 274275.
Durst, R., Jabtinsky-Rubin, K., Dorevitch, A., et al (1993) Idiopathic unconjugated hyperbilirubinaemia (Gilbert's syndrome) and concurrent psychotropic drug administration. Pharmacopsychiatry, 26, 4952.
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Seig, A., Stich, A., Raedsch, R., et al (1986) Gilbert's syndrome: diagnosis by typical serum bilirubin pattern. Clinical Chimica Acta, 154, 4148.
Taylor, S. (1984) Gilbert's syndrome as a cause of postoperative jaundice. Anaesthesia, 39, 12221224.
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BJPsych Bulletin
  • ISSN: 0955-6036
  • EISSN: 1472-1473
  • URL: /core/journals/bjpsych-bulletin
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Co-occurrence of Gilbert's syndrome and psychosis

  • A. S. Mahdi and M. S. Elameer (a1)
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