Skip to main content
×
×
Home

Night sedation in the admission wards of a psychiatric hospital

  • Richard P. W. Fry (a1)
Extract

Since their introduction in the 1960s, benzodiazepine drugs have been widely prescribed for anxiety states and insomnia. Despite the initial hopes for these drugs being non-addictive and not producing tolerance, recent work has shown that there is a well defined withdrawal syndrome (Hallstrom & Lader, 1981; Petursson & Lader, 1981; Tyrer et al, 1981; Tyrer et al, 1983) and that tolerance has also been shown to occur (Aranko et al, 1983; Aranko et al, 1985). There has been widespread concern about these effects. The British National Formulary advocates that “used as hypnotics routine prescribing especially in hospitals is undesirable, and ideally they should be reserved for short courses of treatment in the acutely distressed” and that they should be discontinued as soon as possible. Indeed the Royal College of Psychiatrists' statement on benzodiazepine prescribing and the Committee on Safety of Medicines have recommended that their use as hypnotics should be considered only when the condition is severe, disabling or subjecting the individual to extreme distress. Tyrer & Murphy (1987) have recommended that these drugs are best used for no longer than two weeks in regular dosage.

    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Night sedation in the admission wards of a psychiatric hospital
      Available formats
      ×
      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

      Night sedation in the admission wards of a psychiatric hospital
      Available formats
      ×
      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

      Night sedation in the admission wards of a psychiatric hospital
      Available formats
      ×
Copyright
This is an Open Access article, distributed under the terms of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
References
Hide All
Aranko, K., Mattilsa, M. & Seppala, T. (1983) Development of tolerance and cross tolerance to the psychomotor actions of lorazepan and diazepam in man. British Journal of Clinical Pharmacology, 15, 545552.
Aranko, K., Mattilsa, M., Nuutilla, A. & Pellinen, J. (1985) Benzodiazepines, but not antidepressants or neuroleptics, induce dose-dependent development of tolerance to lorazepam in psychiatric patients. Acta Psychiatrica Scandinavica, 72, 436446.
British National Formulary, 15, (1988) p. 136. Londor: British Medical Association and The Pharmaceutical Society.
Hallstrom, C. & Lader, M. H. (1981) Benzodiazepine withdrawal phenomena. International Pharmacopsychiatry, 16, 235244.
Petursson, H. & Lader, M. H. (1981) Withdrawal from long-term benzodiazepine treatment. British Medical Journal, 283, 643645.
Royal College of Psychiatrists (1988) Benzodiazepines and dependence: a College Statement. Bulletin of the Royal College of Psychiatrists, 12, 107108.
Tyrer, P. & Murphy, S. (1987) The place of benzodiazepines in psychiatric practice. British Journal of Psychiatry, 151, 719723.
Tyrer, P., Owen, R. & Dawling, S. (1983) Gradual withdrawal of diazepam after long therapy. Lancet, i, 14031406.
Tyrer, P., Rutherford, D. & Huggett, T. (1981) Benzodiazepine withdrawal symptoms and propranolol. Lancet, i, 520522.
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

BJPsych Bulletin
  • ISSN: 0955-6036
  • EISSN: 1472-1473
  • URL: /core/journals/bjpsych-bulletin
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Metrics

Abstract views

Total abstract views: 7 *
Loading metrics...

* Views captured on Cambridge Core between 2nd January 2018 - 25th June 2018. This data will be updated every 24 hours.

Night sedation in the admission wards of a psychiatric hospital

  • Richard P. W. Fry (a1)
Submit a response

eLetters

No eLetters have been published for this article.

×

Reply to: Submit a response


Your details


Conflicting interests

Do you have any conflicting interests? *