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Neural plasticity in response to attention training in anxiety

Published online by Cambridge University Press:  23 July 2009

S. Eldar*
Affiliation:
The Adler Center for Research in Child Developmental and Psychopathology, Department of Psychology, Tel Aviv University, Tel Aviv, Israel
Y. Bar-Haim
Affiliation:
The Adler Center for Research in Child Developmental and Psychopathology, Department of Psychology, Tel Aviv University, Tel Aviv, Israel
*
*Address for correspondence: S. Eldar, M.A., The Adler Center for Research in Child Developmental and Psychopathology, Department of Psychology, Tel Aviv University, Tel Aviv69978, Israel. (Email: nitzansh@post.tau.ac.il)

Abstract

Background

Behavioral studies show that attention training can alter threat bias, influence vulnerability to stress and reduce clinical anxiety symptoms. The aim of this study was to examine which cognitive functions of attention processing are modulated by attention training, and how a priori anxiety interacts with the attention training procedure. Specifically, we expected modulation in the P1/N1 event-related potential (ERP) complex if early spatial attention was to be affected by training and modulation in later ERP components (P2, N2, P3) had training affected top-down attentional processes.

Method

Thirty anxious and 30 non-anxious adults performed a modified probe detection task. Electroencephalograms (EEGs) were recorded throughout for later ERP analyses. Half the participants in each anxiety group were randomly assigned to undergo a training procedure designed to divert their attention away from threat and the other half received placebo training.

Results

Anxious participants who were trained to avoid threat showed a linear reduction in response time (RT) to targets replacing neutral faces with the progression of training. This change in RT was not observed among non-anxious participants or among anxious participants who were exposed to placebo training. Following training, the anxious participants who were trained to avoid threat showed a reduction in P2 and P3 mean amplitudes and an enhancement in N2 mean amplitude.

Conclusions

Attention training affects anxious participants whereas non-anxious participants seem not to respond to it. The ERP data suggest that attention training modulates top-down processes of attention control rather than processes of early attention orienting.

Type
Original Articles
Copyright
Copyright © Cambridge University Press 2009

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