Skip to main content
    • Aa
    • Aa

The case for biology in the aetiology of anorexia nervosa1

  • View HTML
    • Send article to Kindle

      To send this article to your Kindle, first ensure is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle.

      Note you can select to send to either the or variations. ‘’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      The case for biology in the aetiology of anorexia nervosa1
      Available formats
      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Dropbox account. Find out more about sending content to Dropbox.

      The case for biology in the aetiology of anorexia nervosa1
      Available formats
      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Google Drive account. Find out more about sending content to Google Drive.

      The case for biology in the aetiology of anorexia nervosa1
      Available formats
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

B. K. Anand & J. R. Brobeck (1951). Localisation of a ‘feeding center’ in hypothalamus of the rat. Proceedings of the Society for Experimental Biology and Medicine 77, 323324.

D. J. Broberg & I. L. Bernstein (1989). Cephalic insulin release in anorexic women. Physiology and Behavior 45, 871874.

R. Bryant-Waugh & B. Lask (1991). Anorexia nervosa in a group of Asian children living in Britain. British Journal of Psychiatry 158, 229233.

T. Buchan & L. D. Gregory (1984). Anorexia nervosa in a black Zimbabwean. British Journal of Psychiatry 145, 326330.

N. Buhrich (1981). Frequency of presentation of anorexia nervosa in Malaysia. Australian and New Zealand Journal of Psychiatry 15, 153155.

M. Buvat-Herbaut , P. Hebbinchuys , A. Lemaire & J. Buvat (1983). Attitudes towards weight, body image, eating, menstruation, pregnancy and sexuality in 81 cases of anorexia nervosa compared to 281 normal control school girls. International Journal of Eating Disorders 2, 4559.

R. C. Casper (1990). Personality features of women with good outcome from restricting anorexia nervosa. Psychosomatic Medicine 52, 156170.

R. C. Casper , G. N. Pandy , J. B. Jaspan & A. H. Rubenstein (1988). Hormone and metabolite plasma levels after oral glucose in bulimia and healthy controls. Biological Psychiatry 24, 663674.

C. R. Cloninger (1987). A systematic model for clinical description and classification of personality variants: a proposal. Archives of General Psychiatry 44, 573588.

R. D. Coddington & H. Bruch (1970). Gastric perceptivity in normal, obese and schizophrenic subjects. Psychosomatics 11, 571579.

A. H. Crisp (1967). The possible significance of some behavioural correlates of weight and carbohydrate intake. Journal of Psychosomatic Research 11, 117131.

T. P. Donohoe (1984). Stress-induced anorexia: implications for anorexia nervosa. Life Sciences 34, 203218.

C. T. Dourish , G. A. Kennett & G. Curzon (1987). The 5-HT-1A agonists 8-OH-DPAT, buspirone and ipsapirone attenuate stress-induced anorexia in rats. Journal of Psychopharmacology 1, 2331.

A. J. Dunn & J. Welch (1991). Stress and endotoxin-induced increases in brain tryptophan and serotonin metabolism depend on sympathetic nervous system activation. Journal of Neurochemistry 57, 16151622.

R. F. Escamilla & H. Lisser (1942). ‘Simmond's disease’. Journal of Clinical Endocrinology 2, 65.

D. H. Gandhi , M. Prakash Appaya & T. Machado (1991). Anorexia nervosa in Asian children. British Journal of Psychiatry 159, 591592.

E. Goodall & T. Silverstone (1988). Differential effect of D-fenfluramine and metergoline on food intake in human subjects. Appetite 11, 215228.

G. M. Goodwin , C. G. Fairburn & P. J. Cowen (1987). The effects of dieting and weight loss on neuroendocrine responses to tryptophan, clonidine and apomorphine in volunteers. Archives of General Psychiatry 44, 952955.

D. J. Haleem , G. A. Kennett & G. Curzon (1988). Adaptation of female rats to stress: shift to male pattern by inhibition of corticosterone synthesis. Brain Research 458, 339347.

M. M. Hetherington & B. J. Rolls (1991). Eating behaviour in eating disorders: response to preloads. Physiology and Behaviour 50, 101108.

N. L. Holden & P. H. Robinson (1988). Anorexia nervosa and bulimia nervosa in British blacks. British Journal of Psychiatry 152, 544549.

A. J. Holland , A. Hall , R. Murray , G. F. M. Russell & A. Crisp (1984). Anorexia nervosa: a study of 34 twin pairs and one set of triplets. British Journal of Psychiatry 145, 414419.

A. J. Holland , N. Sicotte & J. L. Treasure (1988). Anorexia nervosa: evidence for a genetic basis. Journal of Psychosomatic Research 32, 561571.

L. L. Humphrey , R. F. Apple & D. S. Kirschenbaum (1986). Differentiating bulimic-anorexic from normal families using interpersonal and behavioural observational systems. Journal of Consulting and Clinical Psychology 54, 190195.

P. Janet (1907). The Major Symptoms of Hysteria. Macmillan: London.

D. J. Jones , M. M. Fox , H. M. Babigan & H. E. Hutton (1980). Epidemiology of anorexia nervosa in Munroe County, New York: 1960–1976. Psychosomatic Medicine 42, 551558.

P. Kalan , E. Rosegren , O. Lindvall & A. Bjorklund (1989). Hippocampal noradrenaline and serotonin release over 24 hours as measured by the dialysis technique in freely moving rats: correlation to behavioural activity state, effect of handling and tail pinch. European Journal of Neuroscience 1, 181188.

W. H. Kaye , H. E. Gwirtsman , T. D. Brewerton , D. T. George & R. J. Wurtman (1988 a). Bingeing behavior and plasma amino acids: a possible involvement of brain serotonin in bulimia nervosa. Psychiatry Research 23, 3143.

W. H. Kaye , H. E. Gwirstman , D. T. George , D. C. Jimerson & M. H. Ebert (1988 b). CSF 5-HIAA concentrations in anorexia nervosa: reduced values in underweight subjects normalise after weight gain. Biological Psychiatry 23, 102105.

W. H. Kaye , W. Berrettini , H. Gwirtsman & D. T. George (1990 b). Altered cerebrospinal fluid neuropeptide Y and peptide YY immunoreactivity in anorexia and bulimia nervosa. Archives of General Psychiatry 47, 548556.

W. H. Kaye , H. E. Gwirstman , D. T. George & M. H. Ebert (1991). Altered serotonin activity in anorexia nervosa after long-term weight restoration. Archives of General Psychiatry 48, 556562.

G. A. Kennett , F. Chaouloff , M. Marcou & G. Curzon (1986). Female rats are more vulnerable than males in an animal model of depression: the possible role of serotonin. Brain Research 382, 416421.

G. A. Kennett , C. T. Dourish & G. Curzon (1987 a). 5-HT (1B) agonists induce anorexia at a post-synaptic site, 5-HT (1A) agonists cause hyperphagia. European Journal of Pharmacology 141, 429435.

G. A. Kennett , C. T. Dourish & G. Curzon (1987 b). Antidepressant-like action of 5-HT-1A agonists and conventional antidepressants in an animal model of depression. European Journal of Pharmacology 134, 265274.

E. Kog & W. Vandereycken (1989). Family interaction in eating disorder patients and normal controls. International Journal of Eating Disorders 8, 1123.

T. M. Kope & W. H. Sack (1987). Anorexia nervosa in Southeast Asian refugees: a report on three cases. Journal of the American Academy of Child and Adolescent Psychiatry 26, 795796.

L. A. Leiter , N. Huboticky & G. H. Anderson (1987). Effects of L-tryptophan on food intake and selection in lean men and women. Annals of the New York Academy of Sciences 499, 327328.

M. Linniola , M. Virkkunen , M. Scheinin , A. Nuutila , R. Rimon & F. K. Goodwin (1983). Low cerebrospinal fluid 5-HIAA concentration differentiates impulsive from non-impulsive violent behaviour. Life Sciences 33, 26092614.

R. Littlewood (1992). DSM-IV and culture: is the classification internationally valid? Psychiatric Bulletin 16, 257261.

A. R. Lucas , C. M. Beard , W. M. O'Fallon & L. T. Kurland (1988). Anorexia nervosa in Rochester, Minnesota: a 45-year study. Mayo Clinic Proceedings 63, 433442.

V. N. Luine , M. Frankfurt , T. C. Rainbow , A. Biegon & E. Asmitia (1983). Intrahypothalamic 5,7-dihydroxytryptamine facilitates feminine sexual behaviour and decreases (H)imipramine binding and 5-HT uptake. Brain Research 264, 344348.

V. N. Luine , J. E. Thornton , M. Frankfurt & N. J. MacLusky (1987). Effects of hypothalamic serotonin depletion on lordosis behaviour and gonadal hormone receptors. Brain Research 426, 4754.

J. E. Meyer (1961). Das Syndrom der Anorexia Nervosa: Katamnestische Untersuchungen. Archiv für Pschychiatrie und Nervenkrankheiten und Zeitschrift für die Gesämte Neurologie und Psychiatrie 202, 3159.

J. E. Morley & J. E. Blundell (1988). The neurobiological basis of eating disorders: some formulations. Biological Psychiatry 23, 5378.

D. B. Mumford , A. M. Whitehouse & M. Platts (1991). Eating disorders among Asian schoolgirls in Bradford: socio-cultural correlates. British Journal of Psychiatry 158, 222228.

R. L. Norman & C. J. Smith (1991). Restraint inhibits luteinizing hormone and testosterone secretion in intact male rhesus macaques: effects of concurrent naloxone administration. Neuroendocrinology 55, 405415.

A. Nwaefuna (1981). Anorexia nervosa in a developing country. British Journal of Psychiatry 138, 270271.

V. O'Keane , M. O'Hanlon & M. Webb (1991). Prolactin responses throughout the menstrual cycle: evidence for an oestrogen-induced alteration. Clinical Endocrinology 34, 289292.

V. O'Keane , E. Moloney , H. O'Neill , A. O'Connor , C. Smith & T. G. Dinan (1992). Blunted prolactin responses to D-fenfluramine in sociopathy. Evidence for sub-sensitivity of central serotoninergic function. British Journal of Psychiatry 160, 643646.

K. M. Pirke , J. Pahl , V. Schweiger & M. Warnhoff (1985). Metabolic and endocrine indices of starvation in bulimia: a comparison with anorexia nervosa. Psychiatric Research 15, 3339.

A. J. Pumariega , P. Edwards & C. B. Mitchell (1984). Anorexia nervosa in black adolescents. Journal of the American Academy of Child and Adolescent Psychiatry 23, 111114.

P. Robinson & A. Andersen (1985). Anorexia nervosa in American blacks. Journal of Psychosomatic Research 19, 183188.

R. G. Robinson , M. Tortosa & J. Sullivan (1983). Quantitative assessment of psychological state in patients with anorexia nervosa or bulimia: response to caloric stimulus. Psychosomatic Medicine 45, 283291.

N. E. Rowland (1986). Effect of continuous infusions of dexfenfluramine on food intake, body weight and brain amines in rats. Life Sciences 39, 25812586.

T. Silverstone & G. F. M. Russell (1967). ‘Gastric hunger’ contractions in anorexia nervosa. British Journal of Psychiatry 113, 257263.

J. P. Thomas & G. I. Szmukler (1985). Anorexia nervosa in patients of Afro-Caribbean extraction. British Journal of Psychiatry 146, 653656.

S. Traskamn , M. Asberg , L. Bertilsson & L. Sjostrrand (1981). Monoamine metabolites in CSF and suicidal behaviour. Archives of General Psychiatry 38, 631636.

J. L. Treasure & A. J. Holland (1991). Genes and aetiology of eating disorders. In The New Genetics of Mental Illness (ed. P. McGuffin and R. M. Murray ), pp. 198211. Butterworth-Heinemann: Oxford.

J. V. Waller , R. M. Kaufman & F. Deutsch (1940). Anorexia nervosa: a psychosomatic entity. Psychosomatic Medicine 2, 316.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Psychological Medicine
  • ISSN: 0033-2917
  • EISSN: 1469-8978
  • URL: /core/journals/psychological-medicine
Please enter your name
Please enter a valid email address
Who would you like to send this to? *


Full text views

Total number of HTML views: 0
Total number of PDF views: 177 *
Loading metrics...

Abstract views

Total abstract views: 154 *
Loading metrics...

* Views captured on Cambridge Core between September 2016 - 19th September 2017. This data will be updated every 24 hours.