Berger, T. Urech, A. Krieger, T. Stolz, T. Schulz, A. Vincent, A. Moser, C. T. Moritz, S. and Meyer, B. 2017. Effects of a transdiagnostic unguided Internet intervention (‘velibra’) for anxiety disorders in primary care: results of a randomized controlled trial. Psychological Medicine, Vol. 47, Issue. 01, p. 67.
Păsărelu, Costina Ruxandra Andersson, Gerhard Bergman Nordgren, Lise and Dobrean, Anca 2017. Internet-delivered transdiagnostic and tailored cognitive behavioral therapy for anxiety and depression: a systematic review and meta-analysis of randomized controlled trials. Cognitive Behaviour Therapy, Vol. 46, Issue. 1, p. 1.
Arnett, P.A. and Cadden, M. 2016. Encyclopedia of Mental Health.
Ebert, D. D. Donkin, L. Andersson, G. Andrews, G. Berger, T. Carlbring, P. Rozenthal, A. Choi, I. Laferton, J. A. C. Johansson, R. Kleiboer, A. Lange, A. Lehr, D. Reins, J. A. Funk, B. Newby, J. Perini, S. Riper, H. Ruwaard, J. Sheeber, L. Snoek, F. J. Titov, N. Ünlü Ince, B. van Bastelaar, K. Vernmark, K. van Straten, A. Warmerdam, L. Salsman, N. and Cuijpers, P. 2016. Does Internet-based guided-self-help for depression cause harm? An individual participant data meta-analysis on deterioration rates and its moderators in randomized controlled trials. Psychological Medicine, Vol. 46, Issue. 13, p. 2679.
Federici, Stefano Bracalenti, Marco Meloni, Fabio and Luciano, Juan V. 2016. World Health Organization disability assessment schedule 2.0: An international systematic review. Disability and Rehabilitation, p. 1.
Fogliati, V.J. Dear, B.F. Staples, L.G. Terides, M.D. Sheehan, J. Johnston, L. Kayrouz, R. Dear, R. McEvoy, P.M. and Titov, N. 2016. Disorder-specific versus transdiagnostic and clinician-guided versus self-guided internet-delivered treatment for panic disorder and comorbid disorders: A randomized controlled trial. Journal of Anxiety Disorders, Vol. 39, p. 88.
Iakimova, G. Dimitrova, S. and Burté, T. 2016. Peut-on faire une TCC sans thérapeute ? Composantes actives des TCC informatisées pour la dépression. L'Encéphale,
Olthuis, Janine V Watt, Margo C Bailey, Kristen Hayden, Jill A Stewart, Sherry H and Olthuis, Janine V 2016. Cochrane Database of Systematic Reviews.
Rosso, Isabelle M. Killgore, William D.S. Olson, Elizabeth A. Webb, Christian A. Fukunaga, Rena Auerbach, Randy P. Gogel, Hannah Buchholz, Jennifer L. and Rauch, Scott L. 2016. Internet-based cognitive behavior therapy for major depressive disorder: A randomized controlled trial. Depression and Anxiety,
Sandoval, Luis R. Buckey, Jay C. Ainslie, Ricardo Tombari, Martin Stone, William and Hegel, Mark T. 2016. Randomized Controlled Trial of a Computerized Interactive Media-Based Problem Solving Treatment for Depression. Behavior Therapy,
Wilks, Chelsey R. Zieve, Garret G. and Lessing, Hannah K. 2016. Are Trials of Computerized Therapy Generalizable? A Multidimensional Meta-analysis. Telemedicine and e-Health, Vol. 22, Issue. 5, p. 450.
Zarski, Anna-Carlotta Lehr, Dirk Berking, Matthias Riper, Heleen Cuijpers, Pim and Ebert, David Daniel 2016. Adherence to Internet-Based Mobile-Supported Stress Management: A Pooled Analysis of Individual Participant Data From Three Randomized Controlled Trials. Journal of Medical Internet Research, Vol. 18, Issue. 6, p. e146.
Allen, Adrian R. Newby, Jill M. Smith, Jessica and Andrews, Gavin 2015. Internet-based cognitive behavioural therapy (iCBT) for posttraumatic stress disorder versus waitlist control: study protocol for a randomised controlled trial. Trials, Vol. 16, Issue. 1,
Cuijpers, Pim Riper, Heleen and Andersson, Gerhard 2015. Internet-based treatment of depression. Current Opinion in Psychology, Vol. 4, p. 131.
Gamble, Nicholas Boyle, Christopher and Morris, Zoe A 2015. Ethical Practice in Telepsychology. Australian Psychologist, Vol. 50, Issue. 4, p. 292.
Hesser, Hugo 2015. Modeling individual differences in randomized experiments using growth models: Recommendations for design, statistical analysis and reporting of results of internet interventions. Internet Interventions, Vol. 2, Issue. 2, p. 110.
McEvoy, Peter M. Erceg-Hurn, David M. Anderson, Rebecca A. Campbell, Bruce N.C. Swan, Amanda Saulsman, Lisa M. Summers, Mark and Nathan, Paula R. 2015. Group metacognitive therapy for repetitive negative thinking in primary and non-primary generalized anxiety disorder: An effectiveness trial. Journal of Affective Disorders, Vol. 175, p. 124.
Olthuis, Janine V Watt, Margo C Bailey, Kristen Hayden, Jill A Stewart, Sherry H and Olthuis, Janine V 2015. Cochrane Database of Systematic Reviews.
Reynolds, Julia Griffiths, Kathleen M Cunningham, John A Bennett, Kylie and Bennett, Anthony 2015. Clinical Practice Models for the Use of E-Mental Health Resources in Primary Health Care by Health Professionals and Peer Workers: A Conceptual Framework. JMIR Mental Health, Vol. 2, Issue. 1, p. e6.
Richards, Derek Richardson, Thomas Timulak, Ladislav and McElvaney, James 2015. The efficacy of internet-delivered treatment for generalized anxiety disorder: A systematic review and meta-analysis. Internet Interventions, Vol. 2, Issue. 3, p. 272.
Major depressive disorder (MDD) and generalized anxiety disorder (GAD) have the highest co-morbidity rates within the internalizing disorders cluster, yet no Internet-based cognitive behavioural therapy (iCBT) programme exists for their combined treatment.
We designed a six-lesson therapist-assisted iCBT programme for mixed anxiety and depression. Study 1 was a randomized controlled trial (RCT) comparing the iCBT programme (n = 46) versus wait-list control (WLC; n = 53) for patients diagnosed by structured clinical interview with MDD, GAD or co-morbid GAD/MDD. Primary outcome measures were the Patient Health Questionnaire nine-item scale (depression), Generalized Anxiety Disorder seven-item scale (generalized anxiety), Kessler 10-item Psychological Distress scale (distress) and 12-item World Health Organization Disability Assessment Schedule II (disability). The iCBT group was followed up at 3 months post-treatment. In study 2, we investigated the adherence to, and efficacy of the same programme in a primary care setting, where patients (n = 136) completed the programme under the supervision of primary care clinicians.
The RCT showed that the iCBT programme was more effective than WLC, with large within- and between-groups effect sizes found (>0.8). Adherence was also high (89%), and gains were maintained at 3-month follow-up. In study 2 in primary care, adherence to the iCBT programme was low (41%), yet effect sizes were large (>0.8). Of the non-completers, 30% experienced benefit.
Together, the results show that iCBT is effective and adherence is high in research settings, but there is a problem of adherence when translated into the ‘real world’. Future efforts need to be placed on developing improved adherence to iCBT in primary care settings.
This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.
Email your librarian or administrator to recommend adding this journal to your organisation's collection.