Jimenez, Amy M. Lee, Junghee Wynn, Jonathan K. Cohen, Mark S. Engel, Stephen A. Glahn, David C. Nuechterlein, Keith H. Reavis, Eric A. and Green, Michael F. 2016. Abnormal Ventral and Dorsal Attention Network Activity during Single and Dual Target Detection in Schizophrenia. Frontiers in Psychology, Vol. 7,
Rocca, P. Galderisi, S. Rossi, A. Bertolino, A. Rucci, P. Gibertoni, D. Montemagni, C. Sigaudo, M. Mucci, A. Bucci, P. Acciavatti, T. Aguglia, E. Amore, M. Bellomo, A. De Ronchi, D. Dell'Osso, L. Di Fabio, F. Girardi, P. Goracci, A. Marchesi, C. Monteleone, P. Niolu, C. Pinna, F. Roncone, R. Sacchetti, E. Santonastaso, P. Zeppegno, P. and Maj, M. 2016. Social cognition in people with schizophrenia: a cluster-analytic approach. Psychological Medicine, Vol. 46, Issue. 13, p. 2717.
Silverstein, Steven M. 2016. The Neuropsychopathology of Schizophrenia.
Bhagyavathi, Haralahalli D. Mehta, Urvakhsh Meherwan Thirthalli, Jagadisha Kumar, C. Naveen Kumar, J. Keshav Subbakrishna, D.K. and Gangadhar, Bangalore N. 2015. Cascading and combined effects of cognitive deficits and residual symptoms on functional outcome in schizophrenia – A path-analytical approach. Psychiatry Research, Vol. 229, Issue. 1-2, p. 264.
Fretland, Ragnhild A. Andersson, Stein Sundet, Kjetil Andreassen, Ole A. Melle, Ingrid and Vaskinn, Anja 2015. Theory of mind in schizophrenia: Error types and associations with symptoms. Schizophrenia Research, Vol. 162, Issue. 1-3, p. 42.
Green, Michael F. and Horan, William P. 2015. Effort-Based Decision Making in Schizophrenia: Evaluation of Paradigms to Measure Motivational Deficits: Table 1.. Schizophrenia Bulletin, Vol. 41, Issue. 5, p. 1021.
Green, Michael F. Llerena, Katiah and Kern, Robert S. 2015. The “Right Stuff” Revisited: What Have We Learned About the Determinants of Daily Functioning in Schizophrenia?: Fig. 1.. Schizophrenia Bulletin, Vol. 41, Issue. 4, p. 781.
Green, Michael F. Horan, William P. Barch, Deanna M. and Gold, James M. 2015. Effort-Based Decision Making: A Novel Approach for Assessing Motivation in Schizophrenia:. Schizophrenia Bulletin, Vol. 41, Issue. 5, p. 1035.
Holt, Daphne J. Boeke, Emily A. Coombs, Garth DeCross, Stephanie N. Cassidy, Brittany S. Stufflebeam, Steven Rauch, Scott L. and Tootell, Roger B.H. 2015. Abnormalities in personal space and parietal–frontal function in schizophrenia. NeuroImage: Clinical, Vol. 9, p. 233.
Martínez-Domínguez, Sara Penadés, Rafael Segura, Bàrbara González-Rodríguez, Alexandre and Catalán, Rosa 2015. Influence of social cognition on daily functioning in schizophrenia: Study of incremental validity and mediational effects. Psychiatry Research, Vol. 225, Issue. 3, p. 374.
Mueller, D. R. Schmidt, S. J. and Roder, V. 2015. One-Year Randomized Controlled Trial and Follow-Up of Integrated Neurocognitive Therapy for Schizophrenia Outpatients. Schizophrenia Bulletin, Vol. 41, Issue. 3, p. 604.
Romero-Ferreiro, María Verónica Aguado, Luis Rodriguez-Torresano, Javier Palomo, Tomás and Rodriguez-Jimenez, Roberto 2015. Patterns of Emotion Attribution are Affected in Patients with Schizophrenia. The Spanish Journal of Psychology, Vol. 18,
Schlosser, Danielle A. Campellone, Timothy R. Biagianti, Bruno Delucchi, Kevin L. Gard, David E. Fulford, Daniel Stuart, Barbara K. Fisher, Melissa Loewy, Rachel L. and Vinogradov, Sophia 2015. Modeling the role of negative symptoms in determining social functioning in individuals at clinical high risk of psychosis. Schizophrenia Research, Vol. 169, Issue. 1-3, p. 204.
Silverstein, Steven M. and Rosen, Richard 2015. Schizophrenia and the eye. Schizophrenia Research: Cognition, Vol. 2, Issue. 2, p. 46.
Silverstein, Steven M. and Thompson, Judy L. 2015. A vision science perspective on schizophrenia. Schizophrenia Research: Cognition, Vol. 2, Issue. 2, p. 39.
Silverstein, Steven Keane, Brian P. Blake, Randolph Giersch, Anne Green, Michael and KÃ©ri, Szabolcs 2015. Vision in schizophrenia: why it matters. Frontiers in Psychology, Vol. 6,
Silverstein, Steven M. Harms, Michael P. Carter, Cameron S. Gold, James M. Keane, Brian P. MacDonald, Angus Daniel Ragland, J. and Barch, Deanna M. 2015. Cortical contributions to impaired contour integration in schizophrenia. Neuropsychologia, Vol. 75, p. 469.
Tabak, Naomi T. Green, Michael F. Wynn, Jonathan K. Proudfit, Greg H. Altshuler, Lori and Horan, William P. 2015. Perceived emotional intelligence is impaired and associated with poor community functioning in schizophrenia and bipolar disorder. Schizophrenia Research, Vol. 162, Issue. 1-3, p. 189.
Young, Jared W. and Markou, Athina 2015. Translational Rodent Paradigms to Investigate Neuromechanisms Underlying Behaviors Relevant to Amotivation and Altered Reward Processing in Schizophrenia. Schizophrenia Bulletin, Vol. 41, Issue. 5, p. 1024.
Feigenson, Keith A. Keane, Brian P. Roché, Matthew W. and Silverstein, Steven M. 2014. Contour integration impairment in schizophrenia and first episode psychosis: State or trait?. Schizophrenia Research, Vol. 159, Issue. 2-3, p. 515.
Early visual processing deficits are reliably detected in schizophrenia and show relationships to poor real-world functioning. However, the nature of this relationship is complex. Theoretical models and recent studies using statistical modeling approaches suggest that multiple intervening factors are involved. We previously reported that a direct and significant association between visual processing and functional status was mediated by a measure of social perception. The present study examined the contribution of negative symptoms to this model.
We employed structural equation modeling (sem) to test several models of outcome, using data from 174 schizophrenia out-patients. Specifically, we examined the direct and indirect relative contributions of early visual processing, social perception and negative symptoms to functional outcome.
First, we found that, similar to social perception, a measure of negative symptoms mediated the association between visual information processing and functional status. Second, we found that the inclusion of negative symptoms substantially enhanced the explanatory power of the model. Notably, it was the experiential aspect of negative symptoms (avolition and anhedonia) more than the expressive aspect (affective flattening and alogia) that accounted for significant variance in functional outcome, especially in the social component of the construct of functional outcome.
Social perception and negative symptoms play relevant roles in functional impairment in schizophrenia. Both social perception and negative symptoms statistically mediate the connection between visual processing and functional outcome. However, given the lack of association between social perception and negative symptoms, these constructs appear to have an impact on functioning through separate pathways.
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