Chen, Szu-Wei and Chippendale, Tracy 2016. Factors associated with IADL independence: implications for OT practice. Scandinavian Journal of Occupational Therapy, p. 1.
Hajek, André König, Hans-Helmut and Laks, Jerson 2016. Longitudinal Predictors of Functional Impairment in Older Adults in Europe – Evidence from the Survey of Health, Ageing and Retirement in Europe. PLOS ONE, Vol. 11, Issue. 1, p. e0146967.
Hajek, André Luck, T. Brettschneider, C. Posselt, T. Lange, C. Wiese, B. Steinmann, S. Weyerer, S. Werle, J. Pentzek, M. Fuchs, A. Stein, J. Bickel, H. Mösch, E. Wagner, M. Heser, K. Maier, W. Scherer, M. Riedel-Heller, S. G. and König, H.-H. 2016. Factors affecting functional impairment among elderly Germans — Results of a longitudinal study. The journal of nutrition, health & aging,
Ludvigsson, Mikael Marcusson, Jan Wressle, Ewa and Milberg, Anna 2016. Markers of subsyndromal depression in very old persons. International Journal of Geriatric Psychiatry, Vol. 31, Issue. 6, p. 619.
Ylli, Alban Miszkurka, Malgorzata Phillips, Susan P. Guralnik, Jack Deshpande, Nandini and Zunzunegui, Maria Victoria 2016. Clinically relevant depression in old age: An international study with populations from Canada, Latin America and Eastern Europe. Psychiatry Research, Vol. 241, p. 236.
Yohannes, Abebaw M. Müllerová, Hana Hanania, Nicola A. Lavoie, Kim Tal-Singer, Ruth Vestbo, Jorgen Rennard, Steven I. and Wouters, Emil F.M. 2016. Long-term Course of Depression Trajectories in Patients With COPD. Chest, Vol. 149, Issue. 4, p. 916.
Anton, Stephen D. Woods, Adam J. Ashizawa, Tetso Barb, Diana Buford, Thomas W. Carter, Christy S. Clark, David J. Cohen, Ronald A. Corbett, Duane B. Cruz-Almeida, Yenisel Dotson, Vonetta Ebner, Natalie Efron, Philip A. Fillingim, Roger B. Foster, Thomas C. Gundermann, David M. Joseph, Anna-Maria Karabetian, Christy Leeuwenburgh, Christiaan Manini, Todd M. Marsiske, Michael Mankowski, Robert T. Mutchie, Heather L. Perri, Michael G. Ranka, Sanjay Rashidi, Parisa Sandesara, Bhanuprasad Scarpace, Philip J. Sibille, Kimberly T. Solberg, Laurence M. Someya, Shinichi Uphold, Connie Wohlgemuth, Stephanie Wu, Samuel Shangwu and Pahor, Marco 2015. Successful aging: Advancing the science of physical independence in older adults. Ageing Research Reviews, Vol. 24, p. 304.
Bernard, P. Ninot, G. Bernard, P.L. Picot, M.C. Jaussent, A. Tallon, G. and Blain, H. 2015. Effects of a six-month walking intervention on depression in inactive post-menopausal women: a randomized controlled trial. Aging & Mental Health, Vol. 19, Issue. 6, p. 485.
de Guzman, Allan B. Lacampuenga, Prince Edward U. and Lagunsad, Algem Paul V. 2015. Examining the Structural Relationship of Physical Activity, Cognition, Fear of Falling, and Mobility Limitation of Filipino in Nursing Homes. Educational Gerontology, Vol. 41, Issue. 7, p. 527.
Gómez-Gallego, María Gómez-García, Juan and Ato-Lozano, Ester 2015. The mediating role of depression in the association between disability and quality of life in Alzheimer's disease. Aging & Mental Health, p. 1.
Ludvigsson, Mikael Milberg, Anna Marcusson, Jan and Wressle, Ewa 2015. Normal Aging or Depression? A Qualitative Study on the Differences Between Subsyndromal Depression and Depression in Very Old People. The Gerontologist, Vol. 55, Issue. 5, p. 760.
Makizako, Hyuma Shimada, Hiroyuki Doi, Takehiko Tsutsumimoto, Kota Lee, Sangyoon Hotta, Ryo Nakakubo, Sho Harada, Kazuhiro Lee, Sungchul Bae, Seongryu Harada, Kenji and Suzuki, Takao 2015. Cognitive Functioning and Walking Speed in Older Adults as Predictors of Limitations in Self-Reported Instrumental Activity of Daily Living: Prospective Findings from the Obu Study of Health Promotion for the Elderly. International Journal of Environmental Research and Public Health, Vol. 12, Issue. 3, p. 3002.
Overcash, Janine 2015. Assessing the Functional Status of Older Cancer Patients in an Ambulatory Care Visit. Healthcare, Vol. 3, Issue. 3, p. 846.
Riddle, Meghan McQuoid, Douglas R. Potter, Guy G. Steffens, David C. and Taylor, Warren D. 2015. Disability but not social support predicts cognitive deterioration in late-life depression. International Psychogeriatrics, Vol. 27, Issue. 05, p. 707.
Riddle, Daniel L. Perera, Robert A. Nay, William T. and Dumenci, Levent 2015. What Is the Relationship Between Depressive Symptoms and Pain During Functional Tasks in Persons Undergoing TKA? A 6-year Perioperative Cohort Study. Clinical Orthopaedics and Related Research®, Vol. 473, Issue. 11, p. 3527.
Yao, Hiroshi Takashima, Yuki Araki, Yuko Uchino, Akira Yuzuriha, Takefumi and Hashimoto, Manabu 2015. Leisure-Time Physical Inactivity Associated with Vascular Depression or Apathy in Community-Dwelling Elderly Subjects: The Sefuri Study. Journal of Stroke and Cerebrovascular Diseases, Vol. 24, Issue. 11, p. 2625.
Brady, Anne O. Straight, Chad R. and Evans, Ellen M. 2014. Body Composition, Muscle Capacity, and Physical Function in Older Adults: An Integrated Conceptual Model. Journal of Aging and Physical Activity, Vol. 22, Issue. 3, p. 441.
Covinsky, Kenneth E. Cenzer, Irena Stijacic Yaffe, Kristine O'Brien, Sarah and Blazer, Dan G. 2014. Dysphoria and Anhedonia as Risk Factors for Disability or Death in Older Persons: Implications for the Assessment of Geriatric Depression. The American Journal of Geriatric Psychiatry, Vol. 22, Issue. 6, p. 606.
Hirsch, Jameson K. Walker, Kristin L. Wilkinson, Ross B. and Lyness, Jeffrey M. 2014. Family Criticism and Depressive Symptoms in Older Adult Primary Care Patients: Optimism and Pessimism as Moderators. The American Journal of Geriatric Psychiatry, Vol. 22, Issue. 6, p. 632.
Kulmala, Jenni Hinrichs, Timo Törmäkangas, Timo von Bonsdorff, Mikaela B. von Bonsdorff, Monika E. Nygård, Clas-Håkan Klockars, Matti Seitsamo, Jorma Ilmarinen, Juhani and Rantanen, Taina 2014. Work-related stress in midlife is associated with higher number of mobility limitation in older age—results from the FLAME study. AGE, Vol. 36, Issue. 6,
Depressive symptoms above screening thresholds have been shown to predict functional decline in older adults. Less is known about the impact of subthreshold depression, and whether more symptoms confer significantly greater risk compared to fewer symptoms.
Using data from the Duke Established Populations for Epidemiologic Studies of the Elderly (EPESE) collected over 10 years, we used repeated-measures mixed models to predict functional change by depression status at the prior (index) in-person interview. Depressive symptoms were measured using a modified version of the Center for Epidemiologic Studies Depression Scale (CES-D). Subthreshold depression was operationalized as 6–8 symptoms and CES-D-defined depression as 9–20 symptoms in the previous week. Three domains of functional status were assessed at the subsequent in-person interview: limitations in basic activities of daily living (ADL), instrumental ADL (IADL) and mobility.
Controlling for race, sex, age, education, marital status, cognitive status, health status, self-perceived health, perceived social support and functional status at the index interview, having ⩾6 depressive symptoms predicted an increase of 0.12 IADL limitations 3–4 years later (p=0.03). The incremental effect of CES-D-defined depression (⩾9 symptoms compared to 6–8 symptoms) was not significant, suggesting that the effect of more symptomatic depression did not add to that of subthreshold depression. CES-D score modeled as a continuous variable predicted functional change for all domains, but the relationship was not linear, supporting a possible threshold effect.
The relationship between depressive symptoms and functional change is complex, not necessarily linear, and may vary by tasks assessed.
This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.
Email your librarian or administrator to recommend adding this journal to your organisation's collection.
Full text views reflects the number of PDF downloads, PDFs sent to Google Drive, Dropbox and Kindle and HTML full text views.
Abstract views reflect the number of visits to the article landing page.
* Views captured on Cambridge Core between September 2016 - 26th March 2017. This data will be updated every 24 hours.