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Letter to the Editor: Bias in genetic association studies: effects of research location and resources

  • MARCUS R. MUNAFÒ (a1), ANGELA S. ATTWOOD (a1) and JONATHAN FLINT (a2)
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Copyright

Corresponding author

*Address correspondence to: Marcus R. Munafò, Ph.D., Department of Experimental Psychology, University of Bristol, 12a Priory Road, Bristol BS8 1TU, UK. (Email: marcus.munafo@bristol.ac.uk)

References

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Ioannidis, JP (1998). Effect of the statistical significance of results on the time to completion and publication of randomized efficacy trials. Journal of the American Medical Association 279, 281286.
Ioannidis, JP (2006). Journals should publish all ‘null’ results and should sparingly publish ‘positive’ results. Cancer Epidemiology Biomarkers & Prevention 15, 186.
Ioannidis, JP, Ntzani, EE, Trikalinos, TA, Contopoulos-Ioannidis, DG (2001). Replication validity of genetic association studies. Nature Genetics 29, 306309.
Ioannidis, JP, Trikalinos, TA (2007). An exploratory test for an excess of significant findings. Clinical Trials 4, 245253.
Munafo, MR, Bowes, L, Clark, TG, Flint, J (2005). Lack of association of the COMT (Val158/108 Met) gene and schizophrenia: a meta-analysis of case-control studies. Molecular Psychiatry 10, 765770.
Munafo, MR, Flint, J (2004). Meta-analysis of genetic association studies. Trends in Genetics 20, 439444.
Munafo, MR, Matheson, IJ, Flint, J (2007). Association of the DRD2 gene Taq1A polymorphism and alcoholism: a meta-analysis of case-control studies and evidence of publication bias. Molecular Psychiatry 12, 454461.
Munafo, MR, Timpson, NJ, David, SP, Ebrahim, S, Lawlor, DA (in press). Association of the DRD2 Gene Taq1A polymorphism and smoking behaviour: a meta-analysis and new data. Nicotine & Tobacco Research.
Patsopoulos, NA, Tatsioni, A, Ioannidis, JP (2007). Claims of sex differences: an empirical assessment in genetic associations. Journal of the American Medical Association 298, 880893.
Trikalinos, TA, Ntzani, EE, Contopoulos-Ioannidis, DG, Ioannidis, JP (2004). Establishment of genetic associations for complex diseases is independent of early study findings. European Journal of Human Genetics 12, 762769.

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