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Letter to the Editor: Haloperidol but not dopamine rapidly induces neuronal death: comments on ‘A systematic review of the effects of antipsychotic drugs on brain volume’

  • PHILLIP GRANT (a1)
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      Letter to the Editor: Haloperidol but not dopamine rapidly induces neuronal death: comments on ‘A systematic review of the effects of antipsychotic drugs on brain volume’
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      Letter to the Editor: Haloperidol but not dopamine rapidly induces neuronal death: comments on ‘A systematic review of the effects of antipsychotic drugs on brain volume’
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Corresponding author
(Email: phillip.grant@psychol.uni-giessen.de)
References
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Grant P (2011). Dopamine neurotoxicity, oxidative stress and schizophrenia: in vitro and in vivo studies of peroxisomal reactions to increased dopamine. Doctoral thesis, Justus-Liebig-Universität Giessen (geb.uni-giessen.de/geb/volltexte/2011/8495/index.html). Accessed April 2013.
Moncrieff J, Leo J (2010). A systematic review of the effects of antipsychotic drugs on brain volume. Psychological Medicine 40, 14091422.
Navari S, Dazzan P (2009). Do antipsychotic drugs affect brain structure? A systematic and critical review of MRI findings. Psychological Medicine 39, 17631777.
Noh JS, Kang HJ, Kim EY, Sohn S, Chung YK, Kim SU, Gwag BJ (2000). Haloperidol-induced neuronal apoptosis: role of p38 and c-Jun-NH2-terminal protein kinase. Journal of Neurochemistry 75, 23272334.
Parikh V, Khan MM, Mahadik SP (2003). Differential effects of antipsychotics on expression of antioxidant enzymes and membrane lipid peroxidation in rat brain. Journal of Psychiatric Research 37, 4351.
Zhang XY, Tan YL, Cao LY, Wu GY, Xu Q, Shen Y, Zhou DF (2006). Antioxidant enzymes and lipid peroxidation in different forms of schizophrenia treated with typical and atypical antipsychotics. Schizophrenia Research 81, 291300.
Zipursky RB, Reilly TJ, Murray RM (2012). The myth of schizophrenia as a progressive brain disease. Schizophrenia Bulletin. Published online 7 December 2012. doi:10.1093/schbul/sbs135.
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Psychological Medicine
  • ISSN: 0033-2917
  • EISSN: 1469-8978
  • URL: /core/journals/psychological-medicine
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