Skip to main content
    • Aa
    • Aa
  • Get access
    Check if you have access via personal or institutional login
  • Cited by 16
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Charrel, Claire-Lise Plancke, Laurent Genin, Michaël Defromont, Laurent Ducrocq, François Vaiva, Guillaume and Danel, Thierry 2015. Mortality of people suffering from mental illness: a study of a cohort of patients hospitalised in psychiatry in the North of France. Social Psychiatry and Psychiatric Epidemiology, Vol. 50, Issue. 2, p. 269.

    Crump, Casey Ioannidis, John P.A. Sundquist, Kristina Winkleby, Marilyn A. and Sundquist, Jan 2013. Mortality in persons with mental disorders is substantially overestimated using inpatient psychiatric diagnoses. Journal of Psychiatric Research, Vol. 47, Issue. 10, p. 1298.

    Park, Subin Hong, Jin Pyo Choi, Soon Ho and Ahn, Myung Hee 2013. Clinical and Laboratory Predictors of All Causes Deaths and Alcohol-Attributable Deaths Among Discharged Alcohol-Dependent Patients. Alcoholism: Clinical and Experimental Research, Vol. 37, Issue. 2, p. 270.

    Hayes, Richard D. Chang, Chin-Kuo Fernandes, Andrea Begum, Aysha To, David Broadbent, Matthew Hotopf, Matthew and Stewart, Robert 2012. Associations between symptoms and all-cause mortality in individuals with serious mental illness. Journal of Psychosomatic Research, Vol. 72, Issue. 2, p. 114.

    Nome, Siri and Holsten, Fred 2012. Changes in mortality after first psychiatric admission: A 20-year prospective longitudinal clinical study. Nordic Journal of Psychiatry, Vol. 66, Issue. 2, p. 97.

    James, Anthony Clacey, Joe Seagroatt, Valerie and Goldacre, Michael 2010. Adolescent inpatient psychiatric admission rates and subsequent one-year mortality in England: 1998-2004. Journal of Child Psychology and Psychiatry, Vol. 51, Issue. 12, p. 1395.

    Thangavelu, Karthik Muraleedharan, Vakkat and Hampson, Michele 2010. Recognising serious physical illness in the acutely unwell psychiatric patient. Journal of Psychiatric Intensive Care, Vol. 6, Issue. 01, p. 47.

    Ajdacic-Gross, V. Lauber, C. Baumgartner, M. Malti, T. and Rössler, W. 2009. In-patient suicide - a 13-year assessment. Acta Psychiatrica Scandinavica, Vol. 120, Issue. 1, p. 71.

    Grigoletti, L. Perini, G. Rossi, A. Biggeri, A. Barbui, C. Tansella, M. and Amaddeo, F. 2009. Mortality and cause of death among psychiatric patients: a 20-year case-register study in an area with a community-based system of care. Psychological Medicine, Vol. 39, Issue. 11, p. 1875.

    Honkonen, Heidi Mattila, Aino K. Lehtinen, Klaus Elo, Teemu Haataja, Riina and Joukamaa, Matti 2008. Mortality of Finnish acute psychiatric hospital patients. Social Psychiatry and Psychiatric Epidemiology, Vol. 43, Issue. 8, p. 660.

    Loas, G. Azi, A. Noisette, C. and Yon, V. 2008. Mortalité et causes de décès dans la schizophrénie : étude prospective entre dix et 14 ans d’une cohorte de 150 sujets. L'Encéphale, Vol. 34, Issue. 1, p. 54.

    Tokuda, Yasuharu Obara, Haruo Nakazato, Nobuhiko and Stein, Gerald H. 2008. Acute care hospital mortality of schizophrenic patients. Journal of Hospital Medicine, Vol. 3, Issue. 2, p. 110.

    Politi, Pierluigi Minoretti, Piercarlo Piaggi, Noemi Brondino, Natascia and Emanuele, Enzo 2007. Elevated plasma N-terminal ProBNP levels in unmedicated patients with major depressive disorder. Neuroscience Letters, Vol. 417, Issue. 3, p. 322.

    Emanuele, Enzo Carlin, Maria V. D’Angelo, Angela Peros, Emmanouil Barale, Francesco Geroldi, Diego and Politi, Pierluigi 2006. Elevated plasma levels of lipoprotein(a) in psychiatric patients: a possible contribution to increased vascular risk. European Psychiatry, Vol. 21, Issue. 2, p. 129.

    Thakore, Jogin H. and Spelman, Leona 2006. Obesity and Mental Disorders.

    Räsänen, Sami Hakko, Helinä Viilo, Kaisa Meyer-Rochow, V. Benno and Moring, Juha 2005. Avoidable mortality in long-stay psychiatric patients of Northern Finland. Nordic Journal of Psychiatry, Vol. 59, Issue. 2, p. 103.


Mortality in psychiatric patients 5 to 21 years after hospital admission in Italy

  • P. POLITI (a1), M. PICCINELLI (a1), C. KLERSY (a1), S. MADINI (a1), G. SEGAGNI LUSIGNANI (a1), C. FRATTI (a1) and F. BARALE (a1)
  • DOI:
  • Published online: 01 February 2002

Background. Mental disorders have an increased mortality risk. However, most data have been provided by few countries, some mental disorders have received little attention, long-term studies of large samples are scarce, and insufficient control for confounding variables has lead to artefactual inconsistencies across studies. The aims of this study were: to quantify the mortality risk in psychiatric patients 5 to 21 years after hospital admission and to investigate temporal trends in mortality risk and predictive factors associated with mortality.

Method. All patients admitted to an in-patient psychiatric unit in Italy between 1978 and 1994 were included and vital status and death causes were determined up to 21 years after admission. The observed number of deaths in the sample was compared with the expected number of deaths in the general population. Cox proportional hazard models were fitted to identify predictors of mortality.

Results. Mortality from natural and unnatural causes was higher than expected across all mental disorders. Standardized mortality risk was higher in males (SMR = 4·55; 95% CI 4·17–4·97) than in females (SMR = 3·43; 95% CI 3·07–3·83). Individuals aged less than 40 years were at higher risk in both sexes. The first several years following admission were characterized by a faster decline in survival. Several demographic and clinical factors were predictors of mortality.

Conclusions. Mortality is high in individuals with mental disorders. Prevention of unnatural death causes is an important goal though insufficient to abate excess mortality, since natural death causes account for it to a larger extent.

Corresponding author
Address for correspondence: Dr Pierluigi Politi, Servizio Psichiatrico di Diagnosi e Cura, IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Psychological Medicine
  • ISSN: 0033-2917
  • EISSN: 1469-8978
  • URL: /core/journals/psychological-medicine
Please enter your name
Please enter a valid email address
Who would you like to send this to? *