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Psychiatric morbidity in patients with Parkinson's disease

  • R. G. Brown (a1) and B. MacCarthy (a1)
Abstract
SYNOPSIS

Forty patients with Parkinson's disease underwent a detailed assessment of their psychiatric state using a standardized, semi-structured interview, the Present State Examination. Analysis of the interviews yielded a profile of depressive and neurotic syndromes. Comparing the results with population norms, however, revealed that the patients were distinguished only by high levels of depressed mood and loss of interest and poor concentration. In the majority of patients the range and severity of symptoms fell below the criteria for ‘caseness’. Only four patients could be allocated to an ICD-9 class, two to ‘ neurotic depression’, one to ‘ anxiety state’ and one to ‘ phobic state’. This rate was almost identical to that found in the general population. Broader indices of psychiatric morbidity were related to the patients' levels of disability and cognitive function.

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Corresponding author
1Address for correspondence: Dr R. G. Brown, MRC Human Movement and Balance Unit, National Hospital, Queen Square, London WCIN 3BG.
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R. G. Brown , B. MacCarthy , M. Jahanshahi & C. D. Marsden (1989). The accuracy of self-reported disability in patients with parkinsonism. Archives of Neurology 46, 955959.

M. F. Folstein , S. E. Folstein & P. R. McHugh (1975). ‘Minimental state’: a practical method for grading the mental state of patients for the clinician. Journal of Psychiatric Research 12, 189198.

A.-M. Gotham , R. G. Brown & C. D. Marsden (1986). Depression in Parkinson's disease: a quantitative and qualitative analysis. Journal of Neurology, Neurosurgery and Psychiatry 49, 381389.

M. A. Hamilton (1960). A rating scale for depression. Journal of Neurology, Neurosurgery and Psychiatry 23, 5662.

M. M. Hoehn & M. D. Yahr (1967). Parkinsonism: onset, progression and mortality. Neurology (Minneapolis) 17, 427442.

G. G. Marsh & C. H. Markham (1973). Does levodopa alter depression and psychopathology in parkinsonian patients? Journal of Neurology, Neurosurgery and Psychiatry 36, 925935.

R. Mayeux , Y. Stern , J. Rosen & J. Leventhal (1981). Depression, intellectual impairment and Parkinson's disease. Neurology 31, 645650.

J. Orley & J. K. Wing (1979). Psychiatric disorders in two African villages. Archives of General Psychiatry 36, 513520.

J. D. Parkes (1981). Adverse effects of antiparkinsonian drugs. Drugs 21, 341353.

N. Quinn & F. A. Hussain (1986). Parkinson's disease. British Medical Journal 293, 379382.

J. K. Wing (1983). Use and misuse of the PSE. British Journal of Psychiatry 143, 111117.

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Psychological Medicine
  • ISSN: 0033-2917
  • EISSN: 1469-8978
  • URL: /core/journals/psychological-medicine
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