Skip to main content
    • Aa
    • Aa
  • Get access
    Check if you have access via personal or institutional login
  • Cited by 36
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Worku, Dawit Kibru Yifru, Yared Mamushet Postels, Douglas G and Gashe, Fikre Enquselassie 2014. Prevalence of depression in Parkinson’s disease patients in Ethiopia. Journal of Clinical Movement Disorders, Vol. 1, Issue. 1,

    Ojagbemi, A. A. Akinyemi, R. O. and Baiyewu, O. 2013. Neuropsychiatric symptoms in Nigerian patients with Parkinson's disease. Acta Neurologica Scandinavica, Vol. 128, Issue. 1, p. 9.

    Wengel, Steven McNeilly, Dennis and Burke, William 2012. Parkinson's Disease, Second Edition.

    Ciurli, Paola Formisano, Rita Bivona, Umberto Cantagallo, Anna and Angelelli, Paola 2011. Neuropsychiatric Disorders in Persons With Severe Traumatic Brain Injury. Journal of Head Trauma Rehabilitation, Vol. 26, Issue. 2, p. 116.

    Farabaugh, Amy H. Locascio, Joseph J. Yap, Liang Weintraub, Daniel McDonald, William M. Agoston, Monica Alpert, Jonathan E. Growdon, John and Fava, Maurizio 2009. Pattern of Depressive Symptoms in Parkinson's Disease. Psychosomatics, Vol. 50, Issue. 5, p. 448.

    Mainio, Arja Karvonen, Kaisa Hakko, Helinä Särkioja, Terttu and Räsänen, Pirkko 2009. Parkinson's disease and suicide: a profile of suicide victims with Parkinson's disease in a population-based study during the years 1988-2002 in Northern Finland. International Journal of Geriatric Psychiatry, Vol. 24, Issue. 9, p. 916.

    Messer, Th. and Schmauß, M. 2009. Akutmedizin.

    Santangelo, Gabriella Vitale, Carmine Trojano, Luigi Longo, Katia Cozzolino, Autilia Grossi, Dario and Barone, Paolo 2009. Relationship between depression and cognitive dysfunctions in Parkinson’s disease without dementia. Journal of Neurology, Vol. 256, Issue. 4, p. 632.

    Montel, S. and Bungener, C. 2008. Les troubles anxiodépressifs dans la maladie de Parkinson: une revue de la littérature. Annales Médico-psychologiques, revue psychiatrique, Vol. 166, Issue. 2, p. 85.

    Reijnders, Jennifer S.A.M. Ehrt, Uwe Weber, Wim E.J. Aarsland, Dag and Leentjens, Albert F.G. 2008. A systematic review of prevalence studies of depression in Parkinson's disease. Movement Disorders, Vol. 23, Issue. 2, p. 183.

    Mondolo, F. Jahanshahi, M. Granà, A. Biasutti, E. Cacciatori, E. and Di Benedetto, P. 2007. Evaluation of anxiety in Parkinson’s disease with some commonly used rating scales. Neurological Sciences, Vol. 28, Issue. 5, p. 270.

    Ehrt, Uwe Brønnick, Kolbjørn Leentjens, Albert F. G. Larsen, Jan Petter and Aarsland, Dag 2006. Depressive symptom profile in Parkinson's disease: a comparison with depression in elderly patients without Parkinson's disease. International Journal of Geriatric Psychiatry, Vol. 21, Issue. 3, p. 252.

    Wichowicz, Hubert M. Sławek, Jarosław Derejko, Mirosława and Cubała, Wiesław Jerzy 2006. Factors associated with depression in Parkinson’s disease: a cross-sectional study in a Polish population. European Psychiatry, Vol. 21, Issue. 8, p. 516.

    Dobkin, Roseanne 2005. Psychiatric Issues in Parkinson's Disease.

    Messer, Th. and Schmauß, M. 2005. Das NAW-Buch.

    Angelelli, P. Paolucci, S. Bivona, U. Piccardi, L. Ciurli, P. Cantagallo, A. Antonucci, G. Fasotti, L. Di Santantonio, A. Grasso, M. G. and Pizzamiglio, L. 2004. Development of neuropsychiatric symptoms in poststroke patients: a cross-sectional study. Acta Psychiatrica Scandinavica, Vol. 110, Issue. 1, p. 55.

    Hughes, T. A. Ross, H. F. Mindham, R. H. S. and Spokes, E. G. S. 2004. Mortality in Parkinson's disease and its association with dementia and depression. Acta Neurologica Scandinavica, Vol. 110, Issue. 2, p. 118.

    Yu, Mi Roane, David M. Miner, Christian R. Fleming, Megan and Rogers, John D. 2004. Dimensions of Sexual Dysfunction in Parkinson Disease. The American Journal of Geriatric Psychiatry, Vol. 12, Issue. 2, p. 221.

    Rojo, A. Aguilar, M. Garolera, M.T. Cubo, E. Navas, I. and Quintana, S. 2003. Depression in Parkinson's disease: clinical correlates and outcome. Parkinsonism & Related Disorders, Vol. 10, Issue. 1, p. 23.

    Saint-Cyr, Jean A. 2003. Neuropsychology for Movement Disorders Neurosurgery. Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, Vol. 30, Issue. S1, p. S83.


Psychiatric morbidity in patients with Parkinson's disease

  • R. G. Brown (a1) and B. MacCarthy (a1)
  • DOI:
  • Published online: 01 July 2009

Forty patients with Parkinson's disease underwent a detailed assessment of their psychiatric state using a standardized, semi-structured interview, the Present State Examination. Analysis of the interviews yielded a profile of depressive and neurotic syndromes. Comparing the results with population norms, however, revealed that the patients were distinguished only by high levels of depressed mood and loss of interest and poor concentration. In the majority of patients the range and severity of symptoms fell below the criteria for ‘caseness’. Only four patients could be allocated to an ICD-9 class, two to ‘ neurotic depression’, one to ‘ anxiety state’ and one to ‘ phobic state’. This rate was almost identical to that found in the general population. Broader indices of psychiatric morbidity were related to the patients' levels of disability and cognitive function.

Corresponding author
1Address for correspondence: Dr R. G. Brown, MRC Human Movement and Balance Unit, National Hospital, Queen Square, London WCIN 3BG.
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

R. G. Brown , B. MacCarthy , M. Jahanshahi & C. D. Marsden (1989). The accuracy of self-reported disability in patients with parkinsonism. Archives of Neurology 46, 955959.

M. F. Folstein , S. E. Folstein & P. R. McHugh (1975). ‘Minimental state’: a practical method for grading the mental state of patients for the clinician. Journal of Psychiatric Research 12, 189198.

A.-M. Gotham , R. G. Brown & C. D. Marsden (1986). Depression in Parkinson's disease: a quantitative and qualitative analysis. Journal of Neurology, Neurosurgery and Psychiatry 49, 381389.

M. A. Hamilton (1960). A rating scale for depression. Journal of Neurology, Neurosurgery and Psychiatry 23, 5662.

M. M. Hoehn & M. D. Yahr (1967). Parkinsonism: onset, progression and mortality. Neurology (Minneapolis) 17, 427442.

G. G. Marsh & C. H. Markham (1973). Does levodopa alter depression and psychopathology in parkinsonian patients? Journal of Neurology, Neurosurgery and Psychiatry 36, 925935.

R. Mayeux , Y. Stern , J. Rosen & J. Leventhal (1981). Depression, intellectual impairment and Parkinson's disease. Neurology 31, 645650.

J. Orley & J. K. Wing (1979). Psychiatric disorders in two African villages. Archives of General Psychiatry 36, 513520.

J. D. Parkes (1981). Adverse effects of antiparkinsonian drugs. Drugs 21, 341353.

N. Quinn & F. A. Hussain (1986). Parkinson's disease. British Medical Journal 293, 379382.

J. K. Wing (1983). Use and misuse of the PSE. British Journal of Psychiatry 143, 111117.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Psychological Medicine
  • ISSN: 0033-2917
  • EISSN: 1469-8978
  • URL: /core/journals/psychological-medicine
Please enter your name
Please enter a valid email address
Who would you like to send this to? *