Skip to main content
    • Aa
    • Aa
  • Get access
    Check if you have access via personal or institutional login
  • Cited by 23
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Bosten, J.M. Goodbourn, P.T. Lawrance-Owen, A.J. Bargary, G. Hogg, R.E. and Mollon, J.D. 2015. A population study of binocular function. Vision Research, Vol. 110, p. 34.

    Jia, Ting Ye, Xing Wei, Qiang Xie, Wen Cai, Chunlan Mu, Jingjing Dong, Yi Hu, Panpan Hu, Xinglong Tian, Yanghua and Wang, Kai 2015. Difference in the binocular rivalry rate between depressive episodes and remission. Physiology & Behavior, Vol. 151, p. 272.

    Mast, Fred W. Preuss, Nora Hartmann, Matthias and Grabherr, Luzia 2014. Spatial cognition, body representation and affective processes: the role of vestibular information beyond ocular reflexes and control of posture. Frontiers in Integrative Neuroscience, Vol. 8,

    Preuss, Nora Hasler, Gregor and Mast, Fred W. 2014. Caloric Vestibular Stimulation Modulates Affective Control and Mood. Brain Stimulation, Vol. 7, Issue. 1, p. 133.

    Scocchia, Lisa Valsecchi, Matteo and Triesch, Jochen 2014. Top-down influences on ambiguous perception: the role of stable and transient states of the observer. Frontiers in Human Neuroscience, Vol. 8,

    Law, Phillip C. F. Paton, Bryan K. Thomson, Richard H. Liu, Guang B. Miller, Steven M. and Ngo, Trung T. 2013. Dichoptic Viewing Methods for Binocular Rivalry Research: Prospects for Large-Scale Clinical and Genetic Studies. Twin Research and Human Genetics, Vol. 16, Issue. 06, p. 1033.

    Schmack, Katharina Sekutowicz, Maria Rössler, Hannes Brandl, Eva J. Müller, Daniel J. and Sterzer, Philipp 2013. The influence of dopamine-related genes on perceptual stability. European Journal of Neuroscience, Vol. 38, Issue. 9, p. 3378.

    Blake, Randolph and Wilson, Hugh 2011. Binocular vision. Vision Research, Vol. 51, Issue. 7, p. 754.

    Ngo, Trung T. Mitchell, Philip B. Martin, Nicholas G. and Miller, Steven M. 2011. Psychiatric and genetic studies of binocular rivalry: an endophenotype for bipolar disorder?.. Acta Neuropsychiatrica, Vol. 23, Issue. 01, p. 37.

    Miller, S. M. Hansell, N. K. Ngo, T. T. Liu, G. B. Pettigrew, J. D. Martin, N. G. and Wright, M. J. 2010. Genetic contribution to individual variation in binocular rivalry rate. Proceedings of the National Academy of Sciences, Vol. 107, Issue. 6, p. 2664.

    Öngür, Dost Lundy, Miriam Greenhouse, Ian Shinn, Ann K. Menon, Vinod Cohen, Bruce M. and Renshaw, Perry F. 2010. Default mode network abnormalities in bipolar disorder and schizophrenia. Psychiatry Research: Neuroimaging, Vol. 183, Issue. 1, p. 59.

    Baker, Daniel H. and Graf, Erich W. 2009. On the relation between dichoptic masking and binocular rivalry. Vision Research, Vol. 49, Issue. 4, p. 451.

    Nagamine, Masanori Yoshino, Aihide Miyazaki, Masaki Takahashi, Yoshitomo and Nomura, Soichiro 2009. Difference in binocular rivalry rate between patients with bipolar I and bipolar II disorders. Bipolar Disorders, Vol. 11, Issue. 5, p. 539.

    Krug, K. Brunskill, E. Scarna, A. Goodwin, G. M and Parker, A. J 2008. Perceptual switch rates with ambiguous structure-from-motion figures in bipolar disorder. Proceedings of the Royal Society B: Biological Sciences, Vol. 275, Issue. 1645, p. 1839.

    Nagamine, Masanori Yoshino, Aihide Miyazaki, Masaki Takahashi, Yoshitomo and Nomura, Soichiro 2008. Effects of selective 5-HT1A agonist tandospirone on the rate and rhythmicity of binocular rivalry. Psychopharmacology, Vol. 198, Issue. 2, p. 279.

    Ngo, Trung T. Liu, Guang B. Tilley, Andrew J. Pettigrew, John D. and Miller, Steven M. 2008. The changing face of perceptual rivalry. Brain Research Bulletin, Vol. 75, Issue. 5, p. 610.

    Vandenbroucke, Myriam W. G. Steven Scholte, H. van Engeland, Herman Lamme, Victor A. F. and Kemner, Chantal 2008. Coherent versus Component Motion Perception in Autism Spectrum Disorder. Journal of Autism and Developmental Disorders, Vol. 38, Issue. 5, p. 941.

    Been, Gregory Ngo, Trung T. Miller, Steven M. and Fitzgerald, Paul B. 2007. The use of tDCS and CVS as methods of non-invasive brain stimulation. Brain Research Reviews, Vol. 56, Issue. 2, p. 346.

    Carter, Olivia L. Hasler, Felix Pettigrew, John D. Wallis, Guy M. Liu, Guang B. and Vollenweider, Franz X. 2007. Psilocybin links binocular rivalry switch rate to attention and subjective arousal levels in humans. Psychopharmacology, Vol. 195, Issue. 3, p. 415.

    Miller, Steven M. and Ngo, Trung T. 2007. Studies of caloric vestibular stimulation: implications for the cognitive neurosciences, the clinical neurosciences and neurophilosophy. Acta Neuropsychiatrica, Vol. 19, Issue. 03, p. 183.


Slow binocular rivalry in bipolar disorder

  • S. M. MILLER (a1), B. D. GYNTHER (a1), K. R. HESLOP (a1), G. B. LIU (a1), P. B. MITCHELL (a1), T. T. NGO (a1), J. D. PETTIGREW (a1) and L. B. GEFFEN (a1)
  • DOI:
  • Published online: 01 May 2003

Background. The rate of binocular rivalry has been reported to be slower in subjects with bipolar disorder than in controls when tested with drifting, vertical and horizontal gratings of high spatial frequency.

Method. Here we assess the rate of binocular rivalry with stationary, vertical and horizontal gratings of low spatial frequency in 30 subjects with bipolar disorder, 30 age- and sex-matched controls, 18 subjects with schizophrenia and 18 subjects with major depression. Along with rivalry rate, the predominance of each of the rivaling images was assessed, as was the distribution of normalized rivalry intervals.

Results. The bipolar group demonstrated significantly slower rivalry than the control, schizophrenia and major depression groups. The schizophrenia and major depression groups did not differ significantly from the control group. Predominance values did not differ according to diagnosis and the distribution of normalized rivalry intervals was well described by a gamma function in all groups.

Conclusions. The results provide further evidence that binocular rivalry is slow in bipolar disorder and demonstrate that rivalry predominance and the distribution of normalized rivalry intervals are not abnormal in bipolar disorder. It is also shown by comparison with previous work, that high strength stimuli more effectively distinguish bipolar from control subjects than low strength stimuli. The data on schizophrenia and major depression suggest the need for large-scale specificity trials. Further study is also required to assess genetic and pathophysiological factors as well as the potential effects of state, medication, and clinical and biological subtypes.

Corresponding author
Dr Steven M. Miller, Cognitive Psychophysiology Laboratory, Central Clinical School, Edith Cavell Building, Herston, Queensland 4006, Australia.
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Psychological Medicine
  • ISSN: 0033-2917
  • EISSN: 1469-8978
  • URL: /core/journals/psychological-medicine
Please enter your name
Please enter a valid email address
Who would you like to send this to? *