Skip to main content
×
Home
    • Aa
    • Aa

6-n-Propylthiouracil sensitivity and obesity status among ethnically diverse children

  • Janice C Baranowski (a1), Tom Baranowski (a1), Alicia Beltran (a1), Kathy B Watson (a1), Russell Jago (a2), Margaret Callie (a1), Mariam Missaghian (a3) and Beverly J Tepper (a4)...
Abstract
AbstractObjective

To examine the relationship of 6-n-propylthiouracil (PROP) sensitivity to BMI while statistically controlling for demographic characteristics in two age groups of children: 9–10 years and 17–18 years (n 1551).

Design

Cross-sectional design with a multi-ethnic (White, African-American, Hispanic, Other) sample of 813 children aged 9–10 years and 738 children aged 17–18 years. Children were recruited from local elementary and high schools with at least 30 % minority ethnic enrolment. Children’s height, weight and waist circumference were measured along with their PROP taster status. PROP was measured using two paper discs, one impregnated with NaCl (1·0 mol/l) and the other with PROP solution (0·50 mmol/l).

Results

A significant PROP sensitivity by socio-economic status (SES) interaction term (P = 0·010) was detected wherein supertasters had the largest BMI percentile and Z-score, but only among the group with highest SES.

Conclusions

The results suggest that other factors overwhelmed the influence of PROP sensitivity on adiposity in lower-SES groups. The percentage of variance accounted for by the interaction term was about 1 %. Thus, PROP supertasters had the largest BMI percentile and Z-score, but only among the highest-SES group.

  • View HTML
    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      6-n-Propylthiouracil sensitivity and obesity status among ethnically diverse children
      Available formats
      ×
      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Dropbox account. Find out more about sending content to Dropbox.

      6-n-Propylthiouracil sensitivity and obesity status among ethnically diverse children
      Available formats
      ×
      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Google Drive account. Find out more about sending content to Google Drive.

      6-n-Propylthiouracil sensitivity and obesity status among ethnically diverse children
      Available formats
      ×
Copyright
Corresponding author
*Corresponding author: Email jbaranow@bcm.tmc.edu
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

1. CL Ogden , MD Carroll & KM Flegal (2008) High body mass index for age among US children and adolescents, 2003–2006. JAMA 299, 24012405.

2. T Baranowski (2006) Advances in basic behavioral research will make the most important contributions to effective dietary change programs at this time. J Am Diet Assoc 106, 808811.

3. BJ Tepper & NV Ullrich (2002) Influence of genetic taste sensitivity to 6-n-propylthiouracil (PROP), dietary restraint and disinhibition on body mass index in middle-aged women. Physiol Behav 75, 305312.

4. BJ Tepper , CM Christensen & J Cao (2001) Development of brief methods to classify individuals by PROP taster status. Physiol Behav 73, 571577.

7. GL Goldstein , H Daun & BJ Tepper (2005) Adiposity in middle-aged women is associated with genetic taste blindness to 6-n-propylthiouracil. Obes Res 13, 10171023.

8. A Drewnowski , SA Henderson & JE Cockroft (2007) Genetic sensitivity to 6-n-propylthiouracil has no influence on dietary patterns, body mass indexes, or plasma lipid profiles of women. J Am Diet Assoc 107, 13401348.

9. KL Keller & BJ Tepper (2004) Inherited taste sensitivity to 6-n-propylthiouracil in diet and body weight in children. Obes Res 12, 904912.

10. JC Lumeng , TM Cardinal , JR Sitto (2008) Ability to taste 6-n-propylthiouracil and BMI in low-income preschool-aged children. Obesity (Silver Spring) 16, 15221528.

11. JA Mennella , MY Pepino & DR Reed (2005) Genetic and environmental determinants of bitter perception and sweet preferences. Pediatrics 115, e216e222.

13. TJ Cole , MS Faith , A Pietrobelli (2005) What is the best measure of adiposity change in growing children: BMI, BMI %, BMI z-score or BMI centile? Eur J Clin Nutr 59, 419425.

15. SL Mumford , AM Siega-Riz , A Herring (2008) Dietary restraint and gestational weight gain. J Am Diet Assoc 108, 16461653.

16. CA Yackinous & JX Guinard (2002) Relation between PROP (6-n-progylthiouracil) taster status, taste anatomy and dietary intake measures for young men and women. Appetite 38, 201209.

17. VP Wickramasinghe , GJ Cleghorn , KA Edmiston (2005) Validity of BMI as a measure of obesity in Australian white Caucasian and Australian Sri Lankan children. Ann Hum Biol 32, 6071.

18. J Cohen (1988) Statistical Power Analysis for the Behavioral Sciences, revised ed. Hillsdale, NJ: Lawrence Erlbaum Associates, Inc.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Public Health Nutrition
  • ISSN: 1368-9800
  • EISSN: 1475-2727
  • URL: /core/journals/public-health-nutrition
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords:

Metrics

Full text views

Total number of HTML views: 2
Total number of PDF views: 36 *
Loading metrics...

Abstract views

Total abstract views: 59 *
Loading metrics...

* Views captured on Cambridge Core between September 2016 - 30th May 2017. This data will be updated every 24 hours.