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Adherence to a Mediterranean diet and risk of diabetes: a systematic review and meta-analysis

  • Lukas Schwingshackl (a1), Benjamin Missbach (a1), Jürgen König (a1) and Georg Hoffmann (a1)
Abstract
Objective

Adherence to a Mediterranean diet is associated with significant improvements in health status. However, to date no systematic review and meta-analysis has summarized the effects of Mediterranean diet adherence on the risk of type 2 diabetes mellitus.

 Design

Electronic searches for randomized controlled trials and cohort studies were performed in MEDLINE, SCOPUS, EMBASE and the Cochrane Trial Register until 2 April 2014. Pooled effects were calculated by an inverse-variance random-effect meta-analysis using the statistical software Review Manager 5·2 by the Cochrane Collaboration.

 Setting

Meta-analysis of randomized controlled trials and cohort studies.

 Subjects

Eligibility criteria: 19+years of age.

 Results

One randomized controlled trial and eight prospective cohort studies (122 810 subjects) published between 2007 and 2014 were included for meta-analysis. For highest v. lowest adherence to the Mediterranean diet score, the pooled risk ratio was 0·81 (95 % CI 0·73, 0·90, P<0·0001, I 2=55 %). Sensitivity analysis including only long-term studies confirmed the results of the primary analysis (pooled risk ratio=0·75; 95 % CI 0·68, 0·83, P<0·00001, I 2=0 %). The Egger regression test provided no evidence of substantial publication bias (P=0·254).

 Conclusions

Greater adherence to a Mediterranean diet is associated with a significant reduction in the risk of diabetes (19 %; moderate quality evidence). These results seem to be clinically relevant for public health, in particular for encouraging a Mediterranean-like dietary pattern for primary prevention of type 2 diabetes mellitus.
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Copyright
COPYRIGHT: © The Authors 2014 
Corresponding author
* Corresponding author: Email lukas.schwingshackl@univie.ac.at
References
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1. Hossain, P, Kawar, B & El Nahas, M (2007) Obesity and diabetes in the developing world – a growing challenge. N Engl J Med 356, 213–215.
2. Keys, A, Menotti, A, Karvonen, MJ et al. (1986) The diet and 15-year death rate in the seven countries study. Am J Epidemiol 124, 903–915.
3. Willett, WC, Sacks, F, Trichopoulou, A et al. (1995) Mediterranean diet pyramid: a cultural model for healthy eating. Am J Clin Nutr 61, 6 Suppl., 1402S–1406S.
4. Neel, JV (1962) Diabetes mellitus: a ‘thrifty’ genotype rendered detrimental by ‘progress’? Am J Hum Genet 14, 353–362.
5. Group, TDS (1999) Glucose tolerance and mortality: comparison of WHO and American Diabetes Association diagnostic criteria. The DECODE study group. European Diabetes Epidemiology Group. Diabetes Epidemiology: Collaborative analysis Of Diagnostic criteria in Europe. Lancet 354, 617–621.
6. Yamaoka, K & Tango, T (2005) Efficacy of lifestyle education to prevent type 2 diabetes: a meta-analysis of randomized controlled trials. Diabetes Care 28, 2780–2786.
7. Lindstrom, J, Ilanne-Parikka, P, Peltonen, M et al. (2006) Sustained reduction in the incidence of type 2 diabetes by lifestyle intervention: follow-up of the Finnish Diabetes Prevention Study. Lancet 368, 1673–1679.
8. Li, G, Zhang, P, Wang, J et al. (2008) The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing Diabetes Prevention Study: a 20-year follow-up study. Lancet 371, 1783–1789.
9. Yoon, U, Kwok, LL & Magkidis, A (2013) Efficacy of lifestyle interventions in reducing diabetes incidence in patients with impaired glucose tolerance: a systematic review of randomized controlled trials. Metabolism 62, 303–314.
10. Sofi, F, Abbate, R, Gensini, GF et al. (2010) Accruing evidence on benefits of adherence to the Mediterranean diet on health: an updated systematic review and meta-analysis. Am J Clin Nutr 92, 1189–1196.
11. Schwingshackl, L & Hoffmann, G (2014) Adherence to Mediterranean diet and risk of cancer: a systematic review and meta-analysis of observational studies. Int J Cancer (Epublication ahead of print version).
12. Jadad, AR, Moore, RA, Carroll, D et al. (1996) Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 17, 1–12.
13. Wells, GA, Shea, B, O’Connell, D et al. (not dated) The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. http://www.ohri.ca/programs/clinical_epidemiology/oxford.htm (accessed October 2013).
14. DerSimonian, R & Laird, N (1986) Meta-analysis in clinical trials. Control Clin Trials 7, 177–188.
15. Higgins, JP, Thompson, SG, Deeks, JJ et al. (2003) Measuring inconsistency in meta-analyses. BMJ 327, 557–560.
16. Egger, M, Davey Smith, G, Schneider, M et al. (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ 315, 629–634.
17. Abiemo, EE, Alonso, A, Nettleton, JA et al. (2013) Relationships of the Mediterranean dietary pattern with insulin resistance and diabetes incidence in the Multi-Ethnic Study of Atherosclerosis (MESA). Br J Nutr 109, 1490–1497.
18. de Koning, L, Chiuve, SE, Fung, TT et al. (2011) Diet-quality scores and the risk of type 2 diabetes in men. Diabetes Care 34, 1150–1156.
19. Martinez-Gonzalez, MA, de la Fuente-Arrillaga, C, Nunez-Cordoba, JM et al. (2008) Adherence to Mediterranean diet and risk of developing diabetes: prospective cohort study. BMJ 336, 1348–1351.
20. Mozaffarian, D, Marfisi, R, Levantesi, G et al. (2007) Incidence of new-onset diabetes and impaired fasting glucose in patients with recent myocardial infarction and the effect of clinical and lifestyle risk factors. Lancet 370, 667–675.
21. Brunner, EJ, Mosdol, A, Witte, DR et al. (2008) Dietary patterns and 15-y risks of major coronary events, diabetes, and mortality. Am J Clin Nutr 87, 1414–1421.
22. InterAct Consortium, Romaguera, D, Guevara, M et al. (2011) Mediterranean diet and type 2 diabetes risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study: the InterAct project. Diabetes Care 34, 1913–1918.
23. Rossi, M, Turati, F, Lagiou, P et al. (2013) Mediterranean diet and glycaemic load in relation to incidence of type 2 diabetes: results from the Greek cohort of the population-based European Prospective Investigation into Cancer and Nutrition (EPIC). Diabetologia 56, 2405–2413.
24. Tobias, DK, Hu, FB, Chavarro, J et al. (2012) Healthful dietary patterns and type 2 diabetes mellitus risk among women with a history of gestational diabetes mellitus. Arch Intern Med 172, 1566–1572.
25. Salas-Salvado, J, Bullo, M, Estruch, R et al. (2014) Prevention of diabetes with Mediterranean diets: a subgroup analysis of a randomized trial. Ann Intern Med 160, 1–10.
26. Tobias, DK, Zhang, C, Chavarro, J et al. (2012) Prepregnancy adherence to dietary patterns and lower risk of gestational diabetes mellitus. Am J Clin Nutr 96, 289–295.
27. Trichopoulou, A, Costacou, T, Bamia, C et al. (2003) Adherence to a Mediterranean diet and survival in a Greek population. N Eng J Med 348, 2599–2608.
28. Guyatt, G, Oxman, AD, Akl, EA et al. (2011) GRADE guidelines: 1. Introduction – GRADE evidence profiles and summary of findings tables. J Clin Epidemiol 64, 383–394.
29. Marin, C, Yubero-Serrano, EM, Lopez-Miranda, J et al. (2013) Endothelial aging associated with oxidative stress can be modulated by a healthy Mediterranean diet. Int J Mol Sci 14, 8869–8889.
30. Schwingshackl, L & Hoffmann, G (2014) Mediterranean dietary pattern, inflammation and endothelial function: a systematic review and meta-analysis of intervention trials. Nutr Metab Cardiovasc Dis (Epublication ahead of print version).
31. Cooper, AJ, Forouhi, NG, Ye, Z et al. (2012) Fruit and vegetable intake and type 2 diabetes: EPIC-InterAct prospective study and meta-analysis. Eur J Clin Nutr 66, 1082–1092.
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