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Diet, nutrition and the prevention of type 2 diabetes

  • NP Steyn (a1), J Mann (a2), PH Bennett (a3), N Temple (a4), P Zimmet (a5), J Tuomilehto (a6), J Lindström (a6) and A Louheranta (a7)...
Abstract
Objectives:

The overall objective of this study was to evaluate and provide evidence and recommendations on current published literature about diet and lifestyle in the prevention of type 2 diabetes.

Design:

Epidemiological and experimental studies, focusing on nutritional intervention in the prevention of type 2 diabetes are used to make disease-specific recommendations. Long-term cohort studies are given the most weight as to strength of evidence available.

Setting and subjects:

Numerous clinical trials and cohort studies in low, middle and high income countries are evaluated regarding recommendations for dietary prevention of type 2 diabetes. These include, among others, the Finnish Diabetes Prevention Study, US Diabetes Prevention Program, Da Qing Study; Pima Indian Study; Iowa Women's Health Study; and the study of the US Male Physicians.

Results:

There is convincing evidence for a decreased risk of diabetes in adults who are physically active and maintain a normal body mass index (BMI) throughout adulthood, and in overweight adults with impaired glucose tolerance who lose weight voluntarily. An increased risk for developing type 2 diabetes is associated with overweight and obesity; abdominal obesity; physical inactivity; and maternal diabetes. It is probable that a high intake of saturated fats and intrauterine growth retardation also contribute to an increased risk, while non-starch polysaccharides are likely to be associated with a decreased risk. From existing evidence it is also possible that omega-3 fatty acids, low glycaemic index foods and exclusive breastfeeding may play a protective role, and that total fat intake and trans fatty acids may contribute to the risk. However, insufficient evidence is currently available to provide convincing proof.

Conclusions:

Based on the strength of available evidence regarding diet and lifestyle in the prevention of type 2 diabetes, it is recommended that a normal weight status in the lower BMI range (BMI 21–23) and regular physical activity be maintained throughout adulthood; abdominal obesity be prevented; and saturated fat intake be less than 7% of the total energy intake.

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Corresponding author
*Corresponding author: Email nelia.steyn@mrc.ac.za
References
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1King, H, Aubert, RE, Herman, WH. Global burden of diabetes, 1995–2025: prevalence, numerical estimates, and projections. Diabetes Care 1998; 21: 1414–31.
2Amos, AF, McCarty, DJ, Zimmet, P. The rising global burden of diabetes and its complications: estimates and projections to the year 2010. Diabetic Medicine 1997; 14: S7–85.
3Bennett, PH. Type 2 diabetes among the Pima Indians of Arizona: an epidemic attributable to environmental change. Nutrition Reviews 1999; 57: S51–4.
4Lako, JV, Nguyen, VC. Dietary patterns and risk factors of diabetes mellitus among urban indigenous women in Fiji. Asia Pacific Journal of Clinical Nutrition 2001; 10: 188–93.
5Hetzel, B, Michael, T. The Lifestyle Factor: Lifestyle and Health. Melbourne: Penguin, 1987.
6WHO Study Group. Diabetes Mellitus—Technical Report Series 727. Geneva: World Health Organization, 1985.
7Gavin, JR 3rd, Alberti, KGMM, Davidson, MB, et al. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 1997; 20: 1183–97.
8WHO Consultation Group. Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications. Part 1: Diagnosis and Classification of Diabetes Mellitus. Geneva: World Health Organisation, 1999.
9Harris, MI, Eastman, RC, Cowie, CC, Flegal, KM, Eberhardt, MS. Comparison of diabetes diagnostic categories in the US population according to the 1997 American Diabetes Association and 1980–1985 World Health Organization diagnostic criteria. Diabetes Care 1997; 20: 1859–62.
10Bennett, PH. Impact of the new WHO classification and diagnostic criteria. Diabetes Obesity & Metabolism 1999; 1(Suppl. 2): S1–6.
11King, H, Rewers, M. Global estimates for prevalence of diabetes mellitus and impaired glucose tolerance in adults. WHO Ad Hoc Diabetes Reporting Group. Diabetes Care 1993; 16: 157–77.
12Harris, MI, Flegal, KM, Cowie, CC, Eberhardt, MS, Goldstein, DE, Little, RR, Wiedmeyer, HM, Byrd-Holt, DD. Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in US adults. The Third National Health and Nutrition Examination Survey, 1988–1994. Diabetes Care 1998; 21: 518–24.
13Harris, MI, Hadden, WC, Knowler, WC, Bennett, PH. Prevalence of diabetes and impaired glucose tolerance and plasma glucose levels in US population aged 20–74 yr. Diabetes 1987; 36: 523–34.
14Harris, MI. Noninsulin-dependent diabetes mellitus in black and white Americans. Diabetes-Metabolism Reviews 1990; 6: 71–90.
15Flegal, KM, Ezzati, TM, Harris, MI, Haynes, SG, Juarez, RZ, Knowler, WC, Perez-Stable, EJ, Stern, MP. Prevalence of diabetes in Mexican Americans, Cubans, and Puerto Ricans from the Hispanic Health and Nutrition Examination Survey, 1982–1984. Diabetes Care 1991; 14: 628–38.
16Gohdes, D. Diabetes in North American Indians and Alaska natives. In: Harris, MI, Cowie, CC, Stern, MP, eds. Diabetes in America. Washington, USA. National Institutes of Health, 1995.
17Knowler, WC, Pettitt, DJ, Saad, MF, Bennett, PH. Diabetes Mellitus in the Pima Indians: incidence, risk factors and pathogenesis. Diabetes-Metabolism Reviews 1990; 6: 127.
18Mokdad, AH, Bowman, BA, Engelgau, MM, Vinicor, F. Diabetes trends among American Indians and Alaska natives: 1990–1998. Diabetes Care 2001; 24: 1508–9.
19Mokdad, AH, Bowman, BA, Ford, ES, Vinicor, F, Marks, JS, Koplan, JP. The continuing epidemics of obesity and diabetes in the United States. Journal of the American Medical Association 2001; 286: 1195–200.
20Teuscher, T, Baillod, P, Rosman, JB, Teuscher, A. Absence of diabetes in a rural West African population with a high carbohydrate/cassava diet. Lancet 1987; i: 765–8.
21Walker, ARP. Prevalence of diabetes mellitus. Lancet 1966; i: 1163.
22Cosnett, JE. Illness among Natal Indians: a survey of hospital admissions. South African Medical Journal 1957; 31: 1109–15.
23Omar, MAK, Seedat, MA, Motala, AA, Dyer, RB, Becker, P. The prevalence of diabetes mellitus and impaired glucose tolerance in a group of urban South African blacks. South African Medical Journal 1993; 83: 641–3.
24Knowler, WC, Bennett, PH, Hamman, RF, Miller, M. Diabetes incidence and prevalence in Pima Indians: a 19-fold greater incidence than in Rochester, Minnesota. American Journal of Epidemiology 1978; 108: 497505.
25Knowler, WC, Pettitt, DJ, Savage, PJ, Bennett, PH. Diabetes incidence in Pima Indians: contributions of obesity and parental diabetes. American Journal of Epidemiology 1981; 113: 144–56.
26Dowse, GK, Zimmet, PZ, Finch, CF, Collins, VR. Decline in incidence of epidemic glucose intolerance in Nauruans: implications for the “thrifty genotype”. American Journal of Epidemiology 1991; 133: 1093–104.
27Bennett, PH, Knowler, WC. Increasing prevalence of diabetes in the Pima (American) Indians over a ten-year period. In: Waldhausl, WK, ed. Diabetes 1979. Amsterdam: Excerpta Medica, 1979.
28Kleinman, JC, Donahue, RP, Harris, MI, Finucane, FF, Madans, JH, Brock, DB. Mortality among diabetics in a national sample. American Journal of Epidemiology 1988; 128: 389401.
29Gu, K, Cowie, CC, Harris, MI. Mortality in adults with and without diabetes in a national cohort of the US population, 1971–1993. Diabetes Care 1998; 21: 1138–45.
30Roper, NA, Bilous, RW, Kelly, WF, Unwin, NC, Connolly, VM. Excess mortality in a population with diabetes and the impact of material deprivation: longitudinal, population based study. British Medical Journal 2001; 322: 1389–93.
31Morrish, NJ, Wang, SL, Stevens, LK, Fuller, JH, Keen, H. Mortality and causes of death in the WHO multinational study of vascular disease in diabetes. Diabetologia 2001; 44: S14–21.
32Sievers, ML, Nelson, RG, Knowler, WC, Bennett, PH. Impact of NIDDM on mortality and causes of death in Pima Indians. Diabetes Care 1992; 15: 1541–9.
33McLarty, DG, Kinabo, L, Swai, AB. Diabetes in tropical Africa: a prospective study, 1981–7. II. Course and prognosis. British Medical Journal 1990; 300: 1107–10.
34Bale, GS, Entmacher, PS. Estimated life expectancy of diabetics. Diabetes 1977; 26: 434–8.
35Barrett-Connor, E, Wingard, DL. Sex differential in ischemic heart disease mortality in diabetics: a prospective population-based study. American Journal of Epidemiology 1983; 118: 489–96.
36Hu, FB, Stampfer, MJ, Solomon, CG, Liu, S, Willett, WC, Speizer, FE, Nathan, DM, Manson, JE. The impact of diabetes mellitus on mortality from all causes and coronary heart disease in women: 20 years of follow-up. Archives of Internal Medicine 2001; 161: 1717–23.
37Stamler, J, Vaccaro, O, Neaton, JD, Wentworth, D. Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the multiple risk factor intervention trial. Diabetes Care 1993; 16: 434–44.
38Saad, MF, Knowler, WC, Pettitt, DJ, Nelson, RG, Charles, MA, Bennett, PH. A two-step model for development of non-insulin-dependent diabetes. American Journal of Medicine 1991; 90: 229–35.
39Saad, MF, Knowler, WC, Pettitt, DJ, Nelson, RG, Mott, DM, Bennett, PH. Sequential changes in serum insulin concentration during development of non-insulin-dependent diabetes. Lancet 1989; i: 1356–9.
40Shaw, JE, Zimmet, PZ, de Courten, M, Dowse, GK, Chitson, P, Gareeboo, H, Hemraj, F, Fareed, D, Tuomilehto, J, Alberti, KG. Impaired fasting glucose or impaired glucose tolerance. What best predicts future diabetes in Mauritius? Diabetes Care 1999; 22: 399402.
41Gabir, MM, Hanson, RL, Dabelea, D, Imperatore, G, Roumain, J, Bennett, PH, Knowler, WC. The 1997 American Diabetes Association and 1999 World Health Organization criteria for hyperglycemia in the diagnosis and prediction of diabetes. Diabetes Care 2000; 23: 1108–12.
42De Vegt, F, Dekker, JM, Jager, A, Hienkens, E, Kostense, PJ, Stehouwer, CD, Nijpels, G, Bouter, LM, Heine, RJ. Relation of impaired fasting and postload glucose with incident type 2 diabetes in a Dutch population: the Hoorn Study. Journal of the American Medical Association 2001; 285: 2109–13.
43Saad, MF, Knowler, WC, Pettitt, DJ, Nelson, RG, Mott, DM, Bennett, PH. The natural history of impaired glucose tolerance in the Pima Indians. New England Journal of Medicine 1988; 319: 1500–6.
44Edelstein, SL, Knowler, WC, Bain, RP, Andres, R, Barrett-Connor, EL, Dowse, GK, Haffner, SM, Pettitt, DJ, Sorkin, JD, Muller, DC, Collins, VR, Hamman, RF. Predictors of progression from impaired glucose tolerance to NIDDM: an analysis of six prospective studies. Diabetes 1997; 46: 701–10.
45Weyer, C, Bogardus, C, Mott, DM, Pratley, RE. The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus. Journal of Clinical Investigation 1999; 104: 787–94.
46Eschwege, E, Charles, MA, Simon, D, Thibult, N, Balkau, B. From policemen to policies: what is the future for 2-h glucose?: The Kelly West Lecture, 2000. Diabetes Care 2001; 24: 1945–50.
47Balkau, B. The DECODE study. Diabetes epidemiology: collaborative analysis of diagnostic criteria in Europe. Diabetes & Metabolism 2000; 26: 282–6.
48Gabir, MM, Hanson, RL, Dabelea, D, Imperatore, G, Roumain, J, Bennett, PH, Knowler, WC. Plasma glucose and prediction of microvascular disease and mortality: evaluation of 1997 American Diabetes Association and 1999 World Health Organization criteria for diagnosis of diabetes. Diabetes Care 2000; 23: 1113–8.
49Shaw, JE, Hodge, AM, de Courten, M, Chitson, P, Zimmet, PZ. Isolated post-challenge hyperglycaemia confirmed as a risk factor for mortality. Diabetologia 1999; 42: 1050–4.
50Davies, MJ, Raymond, NT, Day, JL, Hales, CN, Burden, AC. Impaired glucose tolerance and fasting hyperglycaemia have different characteristics. Diabetic Medicine 2000; 17: 433–40.
51Tan, CE, Emmanuel, SC, Tan, BY, Jacob, E. Prevalence of diabetes and ethnic differences in cardiovascular risk factors. The 1992 Singapore National Health Survey. Diabetes Care 1999; 22: 241–7.
52Mather, HM, Chaturvedi, N, Fuller, JH. Mortality and morbidity from diabetes in South Asians and Europeans: 11-year follow-up of the Southall Diabetes Survey, London, UK. Diabetic Medicine 1998; 15: 53–9.
53Zimmet, P, Taylor, R, Ram, P, King, H, Sloman, G, Raper, LR, Hunt, D. Prevalence of diabetes and impaired glucose tolerance in the biracial (Melanesian and Indian) population of Fiji: a rural-urban comparison. American Journal of Epidemiology 1983; 118: 673–88.
54Omar, MA, Seedat, MA, Dyer, RB, Motala, AA, Knight, LT, Becker, PJ. South African Indians show a high prevalence of NIDDM and bimodality in plasma glucose distribution patterns. Diabetes Care 1994; 17: 70–3.
55Prior, IA, Davidson, F. The epidemiology of diabetes in Polynesians and Europeans in New Zealand and the Pacific. New Zealand Medical Journal 1966; 65: 375–83.
56Simmons, D. The epidemiology of diabetes and its complications in New Zealand. Diabetic Medicine 1996; 13: 371–5.
57Everhart, JE, Knowler, WC, Bennett, PH. Incidence and risk factors for noninsulin-dependent diabetes. In: Harris, MI, Hamman, RF, eds. Diabetes in America, Diabetes Data Compiled 1984. 1985 NIH Publication No. 85–1468.
58Barnett, AH, Eff, C, Leslie, RD, Pyke, DA. Diabetes in identical twins. A study of 200 pairs. Diabetologia 1981; 20: 8793.
59Newman, B, Selby, JV, King, MC, Slemenda, C, Fabsitz, R, Friedman, GD. Concordance for type 2 (non-insulin-dependent) diabetes mellitus in male twins. Diabetologia 1987; 30: 763–8.
60Serjeantson, SW, Owerbach, D, Zimmet, P, Nerup, J, Thoma, K. Genetics of diabetes in Nauru: effects of foreign admixture, HLA antigens and the insulin-gene-linked polymorphism. Diabetologia 1983; 25: 13–7.
61Knowler, WC, Williams, RC, Pettitt, DJ, Steinberg, AG. Gm3;5,13,14 and type 2 diabetes mellitus: an association in American Indians with genetic admixture. American Journal of Human Genetics 1988; 43: 520–6.
62Gardner, LI Jr, Stern, MP, Haffner, SM, Gaskill, SP, Hazuda, HP, Relethford, JH, Eifler, CW. Prevalence of diabetes in Mexican Americans. Relationship to percent of gene pool derived from native American sources. Diabetes 1984; 33: 8692.
63Kenny, SJ, Aubert, RE, Geiss, LS. Prevalence and incidence of non-insulin-dependent diabetes. In: Harris, MI, Cowie, CC, Stern, MP, eds. Diabetes in America. Washington, USA. National Institutes of Health, 1995.
64Dabelea, D, Hanson, RL, Bennett, PH, Roumain, J, Knowler, WC, Pettitt, DJ. Increasing prevalence of Type II diabetes in American Indian children. Diabetologia 1998; 41: 904–10.
65Fagot-Campagna, A, Pettitt, DJ, Engelgau, MM, Burrows, NR, Geiss, LS, Valdez, R, Beckles, GL, Saaddine, J, Gregg, EW, Williamson, DF, Narayan, KM. Type 2 diabetes among North American children and adolescents: an epidemiologic review and a public health perspective. Journal of Pediatrics 2000; 136: 664–72.
66Dean, HJ, Mundy, RL, Moffatt, M. Non-insulin-dependent diabetes mellitus in Indian children in Manitoba. Canadian Medical Association Journal 1992; 147: 52–7.
67Kitagawa, T, Owada, M, Urakami, T, Yamauchi, K. Increased incidence of non-insulin dependent diabetes mellitus among Japanese schoolchildren correlates with an increased intake of animal protein and fat. Clinical Pediatrics (Philadelphia) 1998; 37: 111–5.
68Savage, PJ, Bennett, PH, Senter, RG, Miller, M. High prevalence of diabetes in young Pima Indians: evidence of phenotypic variation in a genetically isolated population. Diabetes 1979; 28: 937–42.
69Colditz, GA, Willett, WC, Stampfer, MJ, Manson, JE, Hennekens, CH, Arky, RA, Speizer, FE. Weight as a risk factor for clinical diabetes in women. American Journal of Epidemiology 1990; 132: 501–13.
70Kuczmarski, RJ, Flegal, KM, Campbell, SM, Johnson, CL. Increasing prevalence of overweight among US adults. The National Health and Nutrition Examination Surveys, 1960 to 1991. Journal of the American Medical Association 1994; 273: 205–11.
71Shah, M, Hannan, PJ, Jeffery, RW. Secular trend in body mass index in the adult population of three communities from the upper mid-western part of the USA: the Minnesota Heart Health Program. International Journal of Obesity 1991; 15: 499503.
72Federation of American Societies for Experimental Biology Life Sciences Research Office. Third Report on Nutrition Monitoring in the United States. Washington, DC: US Government Printing Office, 1995.
73Bouchard, C, Tremblay, A, Despres, JP, Nadeau, A, Lupien, PJ, Theriault, G, Dussault, J, Moorjani, S, Pinault, S, Fournier, G. The response to long-term overfeeding in identical twins. New England Journal of Medicine 1990; 322: 1477–82.
74Preparation and Use of Food-based Dietary Guidelines. Report of a Joint FAO/WHO Consultation. WHO Technical Report Series No. 880. Geneva: World Health Organization, 1998.
75Schoeller, DA. The importance of clinical research: the role of thermogenesis in human obesity. American Journal of Clinical Nutrition 2001; 73: 511–6.
76Grundy, SM. Multifactorial causation of obesity: implications for prevention. American Journal of Clinical Nutrition 1998; 67(Suppl.): 563S–72S.
77Ravussin, E, Swinburn, BA. Pathophysiology of obesity. Lancet 1992; 340: 404–8.
78National Institutes of Health. The Lipid Research Clinics Population Studies Data Book: The Prevalence Study. (Publication no. 79–1527) Bethesda, MD: NIH, 1979.
79Flatt, JP. Importance of nutrient balance in body weight regulation. Diabetes-Metabolism Reviews 1988; 4: 571–81.
80Shah, M, Garg, A. High-fat and high-carbohydrate diets and energy balance. Diabetes Care 1996; 19: 1142–52.
81Sclafani, A. Dietary obesity models. In: Bjorntorp, P, Brodoff, BN. eds. Obesity. Philadelphia, PA: JB Lippincott, 1992, 241–8.
82 Anonymous. From the Centers for Disease Control and Prevention: daily dietary fat and total food energy intakes: NHANES III, Phase 1, 1988–91. Journal of the American Medical Association 1994; 271: 1309.
83Swinburn, B, Metcalf, P, Lezotte, DC. Long-term (5-year) effects of a reduced fat diet in individuals with glucose intolerance. Diabetes Care 2001; 24: 619–24.
84Astrup, A, Greenwald, G, Melanson, E, Saris, WH, Hill, J. The role of low-fat diets in body weight control:a meta-analysis of ad libitum dietary intervention studies. International Journal of Obesity 2000; 24: 1545–52.
85Chan, JM, Rimm, EB, Colditz, GA, Stampfer, MJ, Willett, WC. Obesity, fat distribution, and weight gain as risk factors for clinical diabetes in men. Diabetes Care 1994; 17: 961–9.
86Boyko, EJ, Fujimoto, WY, Leonetti, DL, Newell-Morris, L. Visceral adiposity and risk of type 2 diabetes: a prospective study among Japanese Americans. Diabetes Care 2000; 23: 465–71.
87Despres, JP. Health consequences of visceral obesity. Annals of Medicine 2001; 33: 534–41.
88James, WPT, Leach, R, Kalamara, E, Shayeghi, M. The worldwide obesity epidemic. Obesity Research 2001; 9: 228S–33S.
89Manson, JE, Rimm, EB, Stampfer, MJ, Colditz, GA, Willett, WC, Krolewski, AS, Rosner, B, Hennekens, CH, Speizer, FE. Physical activity and incidence of non-insulin-dependent diabetes mellitus in women. Lancet 1991; 338: 774–8.
90Manson, JE, Nathan, DM, Krolewski, AS, Stampfer, MJ, Willett, WC, Hennekens, CH. A prospective study of exercise and incidence of diabetes among US male physicians. Journal of the American Medical Association 1992; 268: 63–7.
91Kriska, AM, LaPorte, RE, Pettitt, DJ, Charles, MA, Nelson, RG, Kuller, LH, Bennett, PH, Knowler, WC. The association of physical activity with obesity, fat distribution and glucose intolerance in Pima Indians. Diabetologia 1993; 36: 863–9.
92Helmrich, SP, Ragland, DR, Leung, RW, Paffenbarger, RS Jr. Physical activity and reduced occurrence of non-insulin-dependent diabetes mellitus. New England Journal of Medicine 1991; 325: 147–52.
93McAuley, KA, Williams, SM, Mann, JI, Goulding, A, Chisholm, A, Wilson, N, Story, G, McLay, RT, Harper, MJ, Jones, IE. Intensive lifestyle changes are necessary to improve insulin sensitivity: a randomized controlled trial. Diabetes Care 2002; 25: 445–52.
94Storlien, LH, Baur, LA, Kriketos, AD, Pan, DA, Cooney, GJ, Jenkins, AB, Calvert, GD, Campbell, LV. Dietary fats and insulin action. Diabetologia 1996; 39: 621–31.
95Lichtenstein, AH, Schwab, US. Relationship of dietary fat to glucose metabolism. Atherosclerosis 2000; 150: 227–43.
96Hu, FB, van Dam, RM, Liu, S. Diet and risk of type II diabetes: the role of types of fat and carbohydrate. Diabetologia 2001; 44: 805–17.
97Nagy, K, Levy, J, Grunberger, G. High-fat feeding induces tissue-specific alteration in proportion of activated insulin receptors in rats. Acta Endocrinologica Copenhagen 1990; 122: 361–8.
98Grundleger, ML, Thenen, SW. Decreased insulin binding, glucose transport, and glucose metabolism in soleus muscle of rats fed a high fat diet. Diabetes 1982; 31: 232–7.
99Hedeskov, CJ, Capito, K, Islin, H, Hansen, SE, Thams, P. Long-term fat-feeding-induced insulin resistance in normal NMRI mice: postreceptor changes of liver, muscle and adipose tissue metabolism resembling those of type 2 diabetes. Acta Diabetologica 1992; 29: 14–9.
100Storlien, LH, Jenkins, AB, Chisholm, DJ, Pascoe, WS, Khouri, S, Kraegen, EW. Influence of dietary fat composition on development of insulin resistance in rats. Relationship to muscle triglyceride and omega-3: fatty acids in muscle phospholipid. Diabetes 1991; 40: 280–9.
101Pan, DA, Lillioja, S, Kriketos, AD, Milner, MR, Baur, LA, Bogardus, C, Jenkins, AB, Storlien, LH. Skeletal muscle triglyceride levels are inversely related to insulin action. Diabetes 1997; 46: 983–8.
102Storlien, LH, James, DE, Burleigh, KM, Chisholm, DJ, Kraegen, EW. Fat feeding causes widespread in vivo insulin resistance, decreased energy expenditure, and obesity in rats. American Journal of Physiolgy 1986; 251: E576–83.
103Storlien, LH, Kraegen, EW, Chisholm, DJ, Ford, GL, Bruce, DG, Pascoe, WS. Fish oil prevents insulin resistance induced by high-fat feeding in rats. Science 1987; 237: 885–8.
104Marshall, JA, Hamman, RF, Baxter, J. High-fat, low-carbohydrate diet and the aetiology of non-insulin-dependent diabetes mellitus: the San Luis Valley Diabetes Study. American Journal of Epidemiology 1991; 134: 590603.
105Moses, RG, Shand, JL, Tapsell, LC. The recurrence of gestational diabetes: could dietary differences in fat intake be an explanation? Diabetes Care 1997; 20: 1647–50.
106Feskens, EJM, Virtanen, SM, Räsänen, L, Tuomilehto, J, Stengård, J, Pekkanen, J, Nissinen, A, Kromhout, D. Dietary factors determining diabetes and impaired glucose tolerance. A 20-year follow-up of the Finnish and Dutch cohorts of the Seven Countries Study. Diabetes Care 1995; 18: 1104–12.
107Marshall, JA, Hoag, S, Shetterly, S, Hamman, RF. Dietary fat predicts conversion from impaired glucose tolerance to NIDDM. The San Luis Valley Diabetes Study. Diabetes Care 1994; 17: 50–6.
108Marshall, JA, Bessesen, DH, Hamman, RF. High saturated fat and low starch and fibre are associated with hyperinsuli-nemia in a non-diabetic population: the San Luis Valley Diabetes Study. Diabetologia 1997; 40: 430–8.
109Mayer, EJ, Newman, B, Quesenberry, CP, Selby, JV. Usual dietary fat intake and insulin concentrations in healthy women twins. Diabetes Care 1993; 16: 1459–69.
110Lovejoy, J, DiGirolamo, M. Habitual dietary intake and insulin sensitivity in lean and obese adults. American Journal of Clinical Nutrition 1992; 55: 1174–9.
111Bennett, P, Knowler, W, Baird, H, Butler, W, Pettitt, D, Reid, J. Diet and development of non-insulin-dependent diabetes mellitus: an epidemiological perspective. In: Pozza, B, ed. Diet, Diabetes and Atherosclerosis. New York: Raven Press, 1984, 109–19.
112Lundgren, H, Bengtsson, C, Blohme, G, Isaksson, B, Lapidus, L, Lenner, RA, Saaek, A, Winther, E. Dietary habits and incidence on noninsulin-dependent diabetes mellitus in a population study of women in Gothenburg, Sweden. American Journal of Clinical Nutrition 1989; 49: 708–12.
113Feskens, EJ, Kromhout, D. Cardiovascular risk factors and the 25-year incidence of diabetes mellitus in middle-aged men. The Zutphen Study. American Journal of Epidemiology 1989; 130: 1101–8.
114Feskens, EJ, Bowles, CH, Kromhout, D. Inverse association between fish intake and risk of glucose intolerance in normoglycemic elderly men and women. Diabetes Care 1991; 14: 935–41.
115Colditz, GA, Manson, JE, Stampfer, MJ, Rosner, B, Willett, WC, Speizer, FE. Diet and risk of clinical diabetes in women. American Journal of Clinical Nutrition 1992; 55: 1018–23.
116Salmeron, J, Manson, JE. Stampfer, MJ, Colditz, GA, Wing, AL, Willett, WC. Dietary fiber, glycemic load, and risk of non-insulin-dependent diabetes mellitus in women. Journal of the American Medical Association 1997; 277: 472–7.
117Salmeron, J, Ascherio, A, Rimm, EB, Colditz, GA, Spiegelman, D, Jenkins, DJ, Stampfer, MJ, Wing, AL, Willett, WC. Dietary fiber, glycemic load and risk of NIDDM in men. Diabetes Care 1997; 20: 545–50.
118Salmeron, J, Hu, FB, Manson, JE, Stampfer, MJ, Colditz, GA, Rimm, EB, Willett, WC. Dietary fat intake and risk of type 2 diabetes in women. American Journal of Clinical Nutrition 2001; 73: 1019–26.
119Meyer, KA, Kushi, LH, Jacobs, DR, Folsom, AR. Dietary fat and incidence of type 2 diabetes in older Iowa women. Diabetes Care 2001; 24: 1528–35.
120Kolterman, OG, Greenfield, M, Reaven, GM, Saekow, M, Olefsky, JM. Effect of a high carbohydrate diet on insulin binding to adipocytes and on insulin action in vivo in man. Diabetes 1979; 28: 731–6.
121Beck-Nielsen, H, Pedersen, O, Sorensen, N. Effects of diet on the cellular insulin binding and the insulin sensitivity in young healthy subjects. Diabetologia 1978; 15: 289–96.
122Borkman, M, Campbell, LV, Chisholm, DJ, Storlien, LH. Comparison of the effects on insulin sensitivity of high carbohydrate and high fat diets in normal subjects. Journal of Clinical Endocrinology & Metabolism 1991; 72: 432–7.
123Hjollund, E, Pedersen, O, Richelsen, B, Beck-Nielsen, H, Sorensen, NS. Increased insulin binding to adipocytes and monocytes and increased insulin sensitivity of glucose transport and metabolism in adipocytes from non-insulin-dependent diabetics after a low-fat/high-starch/high-fiber diet. Metabolism 1983; 32: 1067–75.
124Chen, M, Bergman, RN, Porte, D. Insulin resistance and beta-cell dysfunction in aging: the importance of dietary carbohydrate. Journal of Clinical Endocrinology & Metabolism 1988; 67: 951–7.
125Swinburn, BA, Boyce, VL, Bergman, RN, Howard, BV, Bogardus, C. Deterioration in carbohydrate metabolism and lipoprotein changes induced by modern, high fat diet in Pima Indians and Caucasians. Journal of Clinical Endocrinology & Metabolism 1991; 73: 156–65.
126Lovejoy, JC, Windhauser, MM, Rood, JC, de la Bretonne, JA. Effect of a controlled high-fat versus low-fat diet on insulin sensitivity and leptin levels in African-American and Caucasian women. Metabolism 1998; 47: 1520–4.
127Bisschop, PH, de Metz, J, Ackermans, MT, Endert, E, Pijl, H, Kuipers, F, Meijer, AJ, Sauerwein, HP, Romijn, JA. Dietary fat content alters insulin-mediated glucose metabolism in healthy men. American Journal of Clinical Nutrition 2001; 73: 554–9.
128Bo, S, Menato, G, Lezo, A, Signorile, A, Bardelli, C, De Michieli, F, Massobrio, M, Pagano, G. Dietary fat and gestational hyperglycemia. Diabetologia 2001; 44: 972–8.
129Feskens, EJ, Kromhout, D. Habitual dietary intake and glucose tolerance in euglycaemic men: the Zutphen study. International Journal of Epidemiology 1990; 19: 953–9.
130Trevisan, M, Krogh, V, Freudenheim, J, Blake, A, Muti, P, Panico, S, Farinaro, E, Mancini, M, Menotti, A, Ricci, G. Consumption of olive oil, butter and vegetable oils and coronary heart disease risk factors. The Research Group ATS-RF2 of the Italian National Research Council. Journal of the American Medical Association 1990; 263: 688–92.
131Parker, DR, Weiss, ST, Troisi, R, Cassano, PA, Vokonas, PS, Landsberg, L. Relationship of dietary saturated fatty acids and body habitus to serum insulin concentrations: the Normative Aging study. American Journal of Clinical Nutrition 1993; 58: 129–36.
132Folsom, AR, Ma, J, McGovern, PG, Eckfeldt, H. Relation between plasma phospholipid saturated fatty acids and hyperinsulinemia. Metabolism 1996; 45: 223–8.
133Vessby, B, Tengblad, S, Lithell, H. Insulin sensitivity is related to the fatty acid composition of serum lipids and skeletal muscle phospholipids in 70-year-old men. Diabetologia 1994; 37: 1044–50.
134Vessby, B, Aro, A, Skarfors, E, Berglund, L, Salminen, I, Lithell, H. The risk to develop NIDDM is related to the fatty acid composition of the serum cholesterol esters. Diabetes 1994; 43: 1353–7.
135Mooy, JM, Grootenhuis, PA, de Vries, H, Valkenburg, HA, Bouter, LM, Kostense, PJ, Heine, RJ. Prevalence and determinants of glucose intolerance in a Dutch caucasian population. The Hoorn study. Diabetes Care 1995; 18: 1270–3.
136Borkman, M, Storlien, LH, Pan, DA, Jenkins, AB, Chisholm, DJ, Campbell, LV. The relation between insulin sensitivity and the fatty-acid composition of skeletal-muscle phospholipids. New England Journal of Medicine 1993; 328: 238–44.
137Pan, DA, Lillioja, S, Milner, MR, Kriketos, AD, Baur, LA, Bogardus, C, Storlien, LH. Skeletal muscle membrane lipid composition is related to adiposity and insulin action. Journal of Clinical Investigation 1995; 96: 2802–8.
138Maron, DJ, Fair, JM, Haskell, WL. Saturated fat intake and insulin resistance in men with coronary artery disease. The stanford coronary risk intervention project investigators and staff. Circulation 1991; 84: 2020–7.
139Uusitupa, M, Schwab, U, Mäkimattila, S, Karhapää, P, Sarkkinen, E, Maliranta, H, Ågren, J, Penttilä, I. Effects of two high-fat diets with different fatty acid compositions on glucose and lipid metabolism in healthy young women. American Journal of Clinical Nutrition 1994; 59: 1310–6.
140Vessby, B, Gustafsson, I-B, Boberg, J, Karlström, B, Lithell, H, Werner, I. Substituting polyunsaturated for saturated fat as a single change in a Swedish diet: effects on serum lipoprotein metabolism and glucose tolerance in patients with hyperlipoproteinaemia. European Journal of Clinical Investigation 1980; 10: 193202.
141Vessby, B, Uusitupa, M, Hermansen, K, Riccardi, G, Rivellese, AA, Tapsell, LC, Nälsen, C, Berglund, L, Louheranta, A, Rasmussen, BM, Calvert, GD, Maffettone, A, Pedersen, E, Gustafsson, I-B, Storlien, LH. Substituting dietary saturated for monounsaturated fat impairs insulin sensitivity in healthy men and women: the KANWU study. Diabetologia 2001; 44: 312–9.
142Schwab, US, Niskanen, LK, Maliranta, HM, Savolainen, MJ, Kesäniemi, YA, Uusitupa, MIJ. Lauric and palmitic acid-enriched diets have minimal impact on serum lipid and lipoprotein concentrations and glucose metabolism in healthy young women. Journal of Nutrition 1995; 125: 466–73.
143Louheranta, AM, Turpeinen, AK, Schwab, US, Vidgren, HM, Parviainen, MT, Uusitupa, MIJ. A high-stearic acid diet does not impair glucose tolerance and insulin sensitivity in healthy women. Metabolism 1998; 47: 529–34.
144Alstrup, KK, Gregersen, S, Jensen, HM, Thomsen, JL, Hermansen, K. Differential effects of cis and trans fatty acids on insulin release from isolated mouse islets. Metabolism 1999; 48: 22–9.
145Christiansen, E, Schnider, S, Palmvig, B, Tauber-Lassen, E, Pedersen, O. Intake of a diet high in trans monounsaturated fatty acids or saturated fatty acids. Effects of postprandial insulinemia and glycemia in obese patients with NIDDM. Diabetes Care 1997; 20: 881–7.
146Louheranta, AM, Turpeinen, AK, Vidgren, HM, Schwab, US, Uusitupa, MIJ. A high- trans fatty acid diet and insulin sensitivity in young healthy women. Metabolism 1999; 48: 870–5.
147Borkman, M, Chisholm, DJ, Furler, SM, Storlien, LH, Kraegen, EW, Simons, LA, Chesterman, CN. Effects of fish-oil supplementation on glucose and lipid metabolism in NIDDM. Diabetes 1989; 38: 1314–9.
148Annuzzi, G, Rivellese, A, Capaldo, B, Di Marino, L, Iovine, C, Marotta, G, Riccardi, G. A controlled study on the effects of n -3 fatty acids on lipid and glucose metabolism in non-insulin-dependent diabetic patients. Atherosclerosis 1991; 87: 6573.
149Boberg, M, Pollare, T, Siegbahn, A, Vessby, B. Supplementation with n -3 fatty acids reduces triglycerides but increases PAI-1 in non-insulin-dependent diabetes mellitus. European Journal of Clinical Investigation 1992; 22: 645–50.
150McManus, RM, Jumpson, J, Finegood, DT, Clandinin, MT, Ryan, EA. A comparison of the effects of n -3 fatty acids from linseed oil and fish oil in well controlled type II diabetes. Diabetes Care 1996; 19: 463–7.
151Rivellese, AA, Maffettone, A, Iovine, C, Di Marino, L, Annuzzi, G, Mancini, M, Riccardi, G. Long-term effects of fish oil on insulin resistance and plasma lipoproteins in NIDDM patients with hypertriglyceridemia. Diabetes Care 1996; 19: 1207–13.
152Grundy, SM. The optimal ratio of fat-to-carbohydrate in the diet. Annual Review of Nutrition 1999; 19: 325–41.
153Bray, GA, Popkin, BM. Dietary fat intake does affect obesity. American Journal of Clinical Nutrition 1998; 68: 1157–73.
154Richards, MK, Paeratakul, S, Bray, GA, Popkin, BM. Current theories regarding the influence of diet and the control of obesity. In: Wilson, T, Temple, NJ, eds. Nutritional Health: Strategies for Disease Prevention. Totowa, NJ: Human Press Inc., 2001; 135–50.
155Tsunehara, CH, Leonetti, DL, Fujimoto, WY. Diet of second-generation Japanese-American men with and without non-insulin-dependent diabetes. American Journal of Clinical Nutrition 1990; 52: 731–8.
156Grundy, SM, Denke, M. Dietary influences on serum lipids and lipoproteins. Journal of Lipid Research 1990; 31: 1149–72.
157Nestle, PJ, Carroll, KF, Havenstein, N. Plasma triglyceride response to carbohydrates, fats and caloric intake. Metabolism 1970; 19: 118.
158Mensink, RP, Katan, MB. Effect of dietary fatty acids on serum lipids and lipoproteins: a meta-analysis of 27 trials. Arteriosclerosis and Thrombosis 1992; 12: 911–9.
159Jeppesen, J, Schaaf, P, Jones, C, Zhou, MY, Chen, YD, Reaven, GM. Effects of low-fat, high-carbohydrate diets on risk factors for ischemic heart disease in postmenopausal women. American Journal of Clinical Nutrition 1997; 65: 1027–33.
160Parks, EJ, Hellerstein, MK. Carbohydrate-induced hypertriacylglycerolemia: historical perspective and review of biological mechanisms. American Journal of Nutrition 2000; 71: 412–33.
161Meyer, KA, Kushi, LH, Jacobs, DR, Slavin, J, Sellers, TA, Folsom, AR. Carbohydrates, dietary fiber, and incident type 2 diabetes in older women. American Journal of Clinical Nutrition 2000; 71: 921–30.
162Bessesen, DH. The role of carbohydrates in insulin resistance. Journal of Nutrition 2001; 131: 2782S–6S.
163Reaven, GM. Do high carbohydrate diets prevent the development or attentuate the manifestations (or both) of syndrome X? A viewpoint strong against. Current Opinion in Lipidology 1997; 8: 23–7.
164Rassmussen, OW, Thomsen, C, Hansen, KW, Vesterlund, M, Winther, E, Hermansen, K. Effects on blood pressure, glucose, and lipid levels of a high-monounsaturated fat diet compared with a high-carbohydrate diet in NIDDM subjects. Diabetes Care 1993; 16: 1565–71.
165Krauss, RM, Eckel, RH, Howard, B, et al. AHA dietary guidelines revision 2000: a statement for healthcare professionals from the Nutrition Committee of the American Heart Association. Circulation 2000 2000; 102: 2284–99.
166Carbohydrates in Human Nutrition. Report of a Joint FAO/WHO Expert Consultation. FAO Food and Nutrition Paper 66. Rome: Food and Agriculture Organization of the United Nations, 1998.
167Granfeldt, Y, Hagander, B, Björck, I. Metabolic responses to starch in oat and wheat products. On the importance of food structure, incomplete gelatinization or presence of viscous fibre. European Journal of Clinical Nutrition 1995; 49: 189–99.
168Granfeldt, Y, Björck, I, Hagander, B. On the importance of processing conditions, products thickness and eggs addition, for the glycemic and hormonal responses to pasta—a comparison with white bread made from pasta ingredients. European Journal of Clinical Nutrition 1991; 45: 489.
169Englyst, H, Kingman, S, Cummings, J. Classification and measurement of nutritionally important starch fractions. European Journal of Clinical Nutrition 1992; 46: 33S–50S.
170Holm, J, Koellreutter, B, Wursch, P. Influence of sterilization, drying and oat bran enrichment of pasta on glucose and insulin responses in healthy subjects and on the rate and extent of in vitro starch digestion. European Journal of Clinical Nutrition 1992; 46: 629.
171Jenkins, DJ, Wolever, TM, Taylor, RH, Barker, H, Fielden, H, Baldwin, JM, Bowling, AC, Newman, HC, Jenkins, AL, Goff, DV. Glycemic index of foods: a physiological basis for carbohydrate exchange. American Journal of Clinical Nutrition 1981; 34: 362–6.
172Trowell, HC. Dietary fibre, ischaemic heart disease and diabetes mellitus. Proceeding of the Nutrition Society 1973; 32: 151–7.
173Trowell, HC. Dietary fibre hypothesis of the aetiology of diabetes mellitus. Diabetes 1975; 24: 762–5.
174Feskens, EJ, Loeber, JG, Kromhout, D. Diet and physical activity as determinants of hyperinsulinaemia: the Zutphen Elderly Study. American Journal of Epidemiology 1994; 140: 350–60.
175Tuomilehto, J, Lindstrom, J, Eriksson, JG, Valle, TT, Hamalainen, H, Ilanne-Parikka, P, Keinanen-Kiukaanniemi, S, Laakso, M, Louheranta, A, Rastas, M, Salminen, V, Uusitupa, M. and for the Finnish Diabetes Prevention Study Group Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. New England Journal of Medicine 2001; 344: 1343–50.
176 Diet and exercise dramatically delay type 2 diabetes. Press release of the National Institute of Diabetes and Digestive and Kidney Diseases. August 8, Accessed November 29, 2001 at httpp:/www.nih.gov/news/pr/aug2001/niddk-08.htm.
177McIntosch, M, Miller, C. A diet containing food rich in soluble and insoluble fibre improves glycemic control and reduces hyperlipidemia among patients with type 2 diabetes mellitus. Nutrition Reviews 2001; 59: 52–5.
178Jenkins, DJ, Jenkins, AL. Dietary fiber and the glycemic response. Proceedings of the Society for Experimental Biology and Medicine 1985; 180: 422–31.
179Anderson, JW. Fiber and health: an overview. American Journal of Gastroenterology 1986; 81: 892–7.
180Frost, G, Wilding, J, Beecham, J. Dietary advice based on the glycemic index improves dietary profile and metabolic control in type 2 diabetic patients. Diabetic Medicine 1994; 11: 340–67.
181Brand, JC, Colagiuri, S, Crossman, S, Allen, A, Roberts, DC, Truswell, AS. Low-glycemic index foods improve long-term glycemic control in NIDDM. Diabetes Care 1991; 14: 95101.
182Fontvieille, AM, Rizkalla, SW, Penfornis, A, Acosta, M, Bornet, FR, Slama, G. The use of low glycaemic index foods improves metabolic control of diabetic patients over five weeks. Diabetic Medicine 1992; 9: 444–50.
183Wolever, TMS, Jenkins, DJA, Vuksan, V, Jenkins, AL, Buckley, GC, Wong, GS, Josse, RG. Beneficial effect of a low glycemic index diet in type 2 diabetes. Diabetic Medicine 1992; 9: 451–8.
184Jenkins, DJ, Wolever, TM, Kalmusky, J, et al. Low-glycemic index diet in hyperlipidemia: use of traditional starchy foods. American Journal of Clinical Nutrition 1987; 45: 6671.
185Brand-Miller, JC. The importance of glycemic index in diabetes. American Journal of Clinical Nutrition 1994; 59(Suppl.): 747S–52S.
186Kushi, LH, Meyer, KA, Jacobs, DR. Cereals, legumes, and chronic disease risk reduction: evidence from epidemiologic studies. American Journal of Clinical Nutrition 1999; 70(Suppl): 451S–8S.
187Liu, S, Stampfer, MJ, Hu, FB, Giovannucci, E, Rimm, E, Manson, JE, Hennekens, CH, Willett, WC. Whole-grain consumption and risk of coronary heart disease: results from the Nurses' Health Study. American Journal of Clinical Nutrition 1999; 70: 412–9.
188Jacobs, DR, Meyer, KA, Kushi, LH, Folsom, AR. Whole-grain intake may reduce the risk of ischemic heart disease death in postmenopausal women: the Iowa Women's Health Study. American Journal of Clinical Nutrition 1998; 68: 248–57.
189Department of Health. Dietary Reference Values for Food Energy and Nutrients for the United Kingdom. Report of the Panel on Dietary Reference Values of the Committee on Medical Aspects of Food Policy. London: HMSO, 1991.
190Sullivan, A. Healthy eating: something to chew over? Nursing Standards 2000; 14: 43–6.
191Hannon-Fletcher, M, Hughes, C, O'Kane, MJ, Moles, KW, Barnett, CR, Barnett, YA, In: Basu, TK, Temple, NJ and Garg, ML eds. Antioxidants in Human Health and Disease. Wallingford, UK: CABI Publishing, 1999; 259–69.
192Jain, SK. Oxidative stress, vitamin E and diabetes. In: Basu, TK, Temple, NJ, Garg, ML, eds. Antioxidants in Human Health and Disease. Wallingford, UK: CABI Publishing, 1999; 249–57.
193Salonen, JT, Nyyssonen, K, Tuomainen, TP, Maenpaa, PH, Korpela, H, Kaplan, GA, Lynch, J, Helmrich, SP, Salonen, R. Increased risk of non-insulin dependent diabetes mellitus at low plasma vitamin E concentrations: a four year follow up study in men. British Medical Journal 1995; 311: 1124–7.
194Reunanen, A, Knekt, P, Aaran, RK, Aromaa, A. Serum antioxidants and risk of non-insulin dependent diabetes mellitus. European Journal of Clinical Nutrition 1998; 52: 8993.
195Kao, WH, Folsom, AR, Nieto, FJ, Mo, JP, Watson, RL, Brancati, FL. Serum and dietary magnesium and the risk for type 2 diabetes mellitus: the Atherosclerosis Risk in Communities Study. Archives of Internal Medicine 1999; 159: 2151–9.
196Schwarz, K, Mertz, W. Chromium (III) and the glucose tolerance factor. Archives of Biochemistry and Biophysics 1959; 85: 292–5.
197Lukaski, HC. Chromium as a supplement. Annual Review of Nutrition 1999; 19: 279302.
198Vincent, JB. Quest for the molecular mechanism of chromium action and its relationship to diabetes. Nutrition Reviews 2000; 58(3): 6772.
199Anderson, RA, Polansky, MM, Bryden, NA, Canary, JJ. Supplemental-chromium effects on glucose, insulin, glucagon, and urinary chromium losses in subjects consuming controlled low-chromium diets. American Journal of Clinical Nutrition 1991; 54: 909–16.
200Striffler, JS, Polansky, MM, Anderson, RA. Dietary chromium decreases insulin resistance in rats fed a high-fat, mineral-imbalanced diet. Metabolism 1998; 47: 396400.
201Striffler, JS, Law, JS, Polansky, MM, Bhathena, SJ, Anderson, RA. Chromium improves insulin response to glucose in rats. Metabolism 1995; 44: 1314–20.
202Anderson, RA, Bryden, NA, Polansky, MM, Gautschi, K. Dietary chromium effects on tissue chromium concentrations and chromium absorption in rats. Journal of Trace Elements in Experimental Medicine 1996; 9: 1125.
203Anderson, RA, Cheng, N, Bryden, NA, Polansky, MM, Cheng, N, Chi, J, Feng, J. Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes. Diabetes 1997; 46: 1786–91.
204Stampfer, MJ, Colditz, GA, Willett, WC, Manson, JE, Arky, RA, Hennekens, CH, Speizer, FE. A prospective study of moderate alcohol drinking and risk of diabetes in women. American Journal of Epidemiology 1988; 128: 549–58.
205Rimm, EB, Chan, J, Stampfer, MJ, Colditz, GA, Willett, WC. Prospective study of cigarette smoking, alcohol use, and the risk of diabetes in men. British Medical Journal 1995; 310: 555–9.
206Ajani, UA, Hennekens, CH, Spelsberg, A, Manson, JE. Alcohol consumption and risk of type 2 diabetes mellitus among US male physicians. Archives of Internal Medicine 2000; 160: 1025–30.
207Kao, WH, Puddey, IB, Boland, LL, Watson, RL, Brancati, FL. Alcohol consumption and the risk of type 2 diabetes mellitus: Atherosclerosis Risk in Communities Study. American Journal of Epidemiology 2001; 154: 748–57.
208O'Sullivan, JB. Diabetes mellitus after GDM. Diabetes 1991; 40(Suppl. 2): 131–5.
209Pettitt, DJ, Knowler, WC, Baird, HR, Bennett, PH. Gestational diabetes: infant and maternal complications of pregnancy in relation to third-trimester glucose tolerance in the Pima Indians. Diabetes Care 1980; 3: 458–64.
210Pettitt, DJ, Aleck, KA, Baird, HR, Carraher, MJ, Bennett, PH, Knowler, WC. Congenital susceptibility to NIDDM. Role of intrauterine environment. Diabetes 1988; 37: 622–8.
211Gautier, JF, Wilson, C, Weyer, C, Mott, D, Knowler, WC, Cavaghan, M, Polonsky, KS, Bogardus, C, Pratley, RE. Low acute insulin secretory responses in adult offspring of people with early onset type 2 diabetes. Diabetes 2001; 50: 1828–33.
212Dabelea, D, Hanson, RL, Lindsay, RS, Pettitt, DJ, Imperatore, G, Gabir, MM, Roumain, J, Bennett, PH, Knowler, WC. Intrauterine exposure to diabetes conveys risks for type 2 diabetes and obesity: a study of discordant sibships. Diabetes 2000; 49: 2208–11.
213Hales, CN, Barker, DJ, Clark, PM, Cox, LJ, Fall, C, Osmond, C, Winter, PD. Fetal and infant growth and impaired glucose tolerance at age 64. British Medical Journal 1991; 303: 1019–22.
214Barker, DJP, Hales, CN, Fall, CHD, Osmond, C, Phipps, K, Clark, PMS. Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth. Diabetologia 1993; 36: 62–7.
215Valdez, R, Athens, MA, Thompson, GH, Bradshaw, BS, Stern, MP. Birthweight and adult health outcomes in a biethnic population in the USA. Diabetologia 1994; 37: 624–31.
216McCance, DR, Pettit, DJ, Hanson, RL, Jacobsson, LTH, Knowler, WC, Bennett, PH. Birthweight and non-insulin dependent diabetes: ‘thrifty genotype’, ‘thrifty phenotype’, or ‘surviving small baby genotype’? British Medical Journal 1994; 308: 942–5.
217Curhan, GC, Willett, WC, Rimm, EB, Stampfer, MJ. Birthweight and adult hypertension and diabetes in US men. Abstract. American Journal of Hypertension 1996; 9: 11A.
218Lithell, HO, McKeigue, PM, Berglund, L, Mohsen, R, Lithell, UB, Leon, DA. Relation of size at birth to non-insulin dependent diabetes and insulin concentrations in men aged 50–60 years. British Medical Journal 1996; 312: 406–10.
219Phillips, DIW. Insulin resistance as a programmed response to fetal undernutrition. Diabetologia 1996; 39: 1119–22.
220Barker, DJP. Mothers, Babies and Health in Later Life. Edinburgh: Harcourt Brace & Co. Ltd., 1998.
221McCance, RA, Widdowson, EM. The determinants of growth and form. Proceedings of the Royal Society London B Biological Sciences 1974; 185: 117.
222Stern, MP, Bartley, M, Duggirala, R, Bradshaw, B. Birth weight and the metabolic syndrome: thrifty phenotype or thrifty genotype? Diabetes-Metabolism Research and Reviews 2000; 16: 8893.
223McCance, DR, Pettitt, DJ, Hanson, RL, Jacobsson, LT, Knowler, WC, Bennett, PH. Birth weight and non-insulin dependent diabetes: thrifty genotype, thrifty phenotype, or surviving small baby genotype? British Medical Journal 1994; 308: 942–5.
224Dabelea, D, Pettitt, DJ, Hanson, RL, Imperatore, G, Bennett, PH, Knowler, WC. Birth weight, type 2 diabetes, and insulin resistance in Pima Indian children and young adults. Diabetes Care 1999; 22: 944–50.
225Hales, CN, Desai, M, Ozanne, SE. The thrifty phenotype hypothesis: how does it look after 5 years? Diabetic Medicine 1997; 14: 189–95.
226Lithell, HO, McKeigue, PM, Berglund, L, Mohsen, R, Lithell, UB, Leon, DA. Relation of size at birth to non-insulin dependent diabetes and insulin concentrations in men aged 50–60 years. British Medical Journal 1996; 312: 406–10.
227Hales, CN, Barker, DJ. Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. Diabetologia 1992; 35: 595601.
228Ravelli, ACJ, van der Meulen, JHP, Michels, RP, Osmond, C, Barker, DJ, Hales, CN, Bleker, OP. Glucose tolerance in adults after prenatal exposure to famine. Lancet 1998; 351: 173–7.
229Barker, DJP, Godfrey, KM. Fetal nutrition and cardiovascular disease in adult life. In: Wilson, T, Temple, N, eds. Nutritional Health: Strategies for Prevention. Totowa, NJ: Humana Press, 2001.
230Fall, CHD, Stein, CE, Kumaran, K, Cox, V, Osmond, C, Barker, DJ, Hales, CN. Size at birth, maternal weight, and type 2 diabetes in South India. Diabetic Medicine 1998; 15: 220–7.
231Mathews, F, Yudkin, P, Neil, A. Influence of maternal nutrition on outcome of pregnancy: prospective cohort study. British Medical Journal 1999; 319: 339–43.
232Campbell, DM, Hall, MH, Barker, DJP, Cross, J, Shiell, AW, Godfrey, KM. Diet in pregnancy and the offspring's blood pressure 40 years later. British Journal of Obstetrics and Gynaecology 1996; 103: 273–80.
233Godfrey, K, Robinson, S, Barker, DJP, Osmond, C, Cox, V. Maternal nutrition in early and late pregnancy in relation to placental and fetal growth. British Medical Journal 1996; 312: 410–4.
234Bennett, PH. Type 2 diabetes among the Pima Indians of Arizona: an epidemic attributable to environmental change. Nutrition Reviews 1999; 57: S51–4.
235Pettitt, DJ, Forman, MR, Hanson, RL, Knowler, WC, Bennett, PH. Breastfeeding and incidence of non-insulin-dependent diabetes mellitus in Pima Indians. Lancet 1997; 350: 166–8.
236Young, TK, Martens, PJ, Taback, SP, Sellers, EA, Dean, HJ, Cheang, M, Flett, B. Type 2 diabetes mellitus in children: prenatal and early infancy risk factors among native Canadians. Archives of Pediatrics & Adolescent Medicine 2002; 156: 651–5.
237Pradhan, AD, Manson, JE, Rifai, N, Buring, JE, Ridker, PM. C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. Journal of the American Medical Association 2001; 286: 327–34.
238Festa, A, D'Agostino, R Jr, Mykkanen, L, Tracy, RP, Zaccaro, DJ, Hales, CN, Haffner, SM. Relative contribution of insulin and its precursors to fibrinogen and PAI-1 in a large population with different states of glucose tolerance. The Insulin Resistance Atherosclerosis Study (IRAS). Arteriosclerosis Thrombosis and Vascular Biology 1999; 19: 562–8.
239Pickup, JC, Crook, MA. Is type II diabetes mellitus a disease of the innate immune system? Diabetologia 1998; 41: 1241–8.
240Lindsay, RS, Krakoff, J, Hanson, RL, Bennett, PH, Knowler, WC. Gamma globulin levels predict type 2 diabetes in the Pima Indian population. Diabetes 2001; 50: 1598–603.
241Lindstedt, G, Lundberg, PA, Lapidus, L, Lundgren, H, Bengtsson, C, Bjorntorp, P. Low sex hormone-binding globulin concentration as independent risk factor for development of NIDDM: 12-year follow-up of population study of women in Gothenburg, Sweden. Diabetes 1991; 40: 123–8.
242Haffner, SM, Valdez, RA, Morales, PA, Hazuda, HP, Stern, MP. Decreased sex hormone-binding globulin predicts non-insulin-dependent diabetes mellitus in women but not in men. Journal of Clinical Endocrinology & Metabolism 1993; 77: 5660.
243Haffner, SM, Karhapää, P, Mykkänen, L, Laakso, M. Insulin resistance, body fat distribution and sex hormones in men. Diabetes 1994; 43: 212–9.
244Charles, MA, Pettitt, DJ, McCance, DR, Hanson, RL, Bennett, PH, Knowler, WC. Gravidity, obesity, and non-insulin-dependent diabetes among Pima Indian women. American Journal of Medicine 1994; 97: 250–5.
245Pan, XR, Li, GW, Hu, YH, et al. Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Qing IGT and Diabetes Study. Diabetes Care 1997; 20: 537–44.
246Eriksson, K-F, Lindgarde, F. Prevention of type 2 (non-insulin-dependent) diabetes mellitus by diabetes mellitus by diet and physical exercise: the 6-Year Malmo Feasibility Study. Diabetologia 1991; 34: 891–8.
247Uusitupa, M, Louheranta, A, Lindstrom, J, Valle, T, Sundvall, J, Eriksson, J, Tuomilehto, J. The Finnish Diabetes Prevention Study. British Journal of Nutrition 2000; 83:(Suppl. 1): S137–42.
248Temple, NJ, Nestle, M. Population nutrition, health promotion and government policy. In: Wilson, T, Temple, NJ, eds. Nutritional Health: Strategies for Diseases Prevention. Totowa, NJ: Humana, 2001; 1329.
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